RU2014106437A

RU2014106437A - METHOD FOR DETERMINING A CLINICAL OPTION OF EUTYREOSIS AND HYPOTHYROIDISM

Info

Publication number: RU2014106437A
Application number: RU2014106437/15A
Authority: RU
Inventors: Андрей Валерьевич Ушаков
Original assignee: Андрей Валерьевич Ушаков
Priority date: 2014-02-21
Filing date: 2014-02-21
Publication date: 2015-08-27

Abstract

Способ определения клинического варианта эутиреоза и гипотиреоза путем сопоставления данных лабораторного анализа крови с референтными значениями показателей ТТГ, Т4-свободного и Т3-свободного, отличающийся тем, что оценивается отношение данных лабораторного анализа к процентилям референтных значений показателей таким образом, что при расположении значения ТТГ от нулевого до 25-го процентиля, в сочетании с нахождением Т4-свободного и Т3-свободного между 25-м и 75-м процентилями выносят суждение об эутиреозе оптимума, при расположении значения ТТГ от 25-го до 50-го процентиля, в сочетании с нахождением Т4-свободного и Т3-сободного в пределах референтных границ выносят суждение об эутиреозе преднапряжения, при расположении значения ТТГ от 50-го до 100-го процентиля, в сочетании с нахождением Т4-свободного и Т3-свободного в пределах референтных границ выносят суждение об эутиреозе напряжения, при увеличении значения ТТГ более 100-го процентиля, в сочетании с расположением Т4-свободного и Т3-свободного между 25-м и 75-процентилями референтного промежутка выносят суждение о компенсированном гипотиреозе, при увеличении значения ТТГ более 100-го процентиля, в сочетании с расположением Т4-свободного от нулевого до 25-го процентиля, а Т3-свободного от 25-го до 75-го процентиля выносят суждение о субкомпенсированном гипотиреозе, при увеличении значения ТТГ более 100-го процентиля, в сочетании с расположением Т4-свободного менее нулевого процентиля, а Т3-свободного менее 25-го процентиля выносят суждение о декомпенсированном гипотиреозе.A method for determining the clinical variant of euthyroidism and hypothyroidism by comparing laboratory blood analysis data with reference values of TSH, T4-free and T3-free indicators, characterized in that the ratio of laboratory analysis data to percentiles of reference values of indicators is estimated so that when the TSH value is from zero to the 25th percentile, in combination with finding T4-free and T3-free between the 25th and 75th percentiles, they make an opinion on the euthyroidism of the optimum, with the value TSH from the 25th to the 50th percentile, in combination with the location of the T4-free and T3-free within the reference boundaries, make a judgment about pre-stress euthyroidism, when the TSH value is from the 50th to the 100th percentile, in combination with finding T4-free and T3-free within the reference boundaries makes a judgment about stress euthyroidism, with an increase in the TSH value of more than 100th percentile, in combination with the location of T4-free and T3-free between the 25th and 75th percentiles of the reference interval judgment of compensated hypothyroidism, with an increase in TSH values above the 100th percentile, in combination with the location of T4-free from zero to 25th percentile, and T3-free from 25th to 75th percentile make a judgment on subcompensated hypothyroidism, with increasing value TSH over 100 percentile, in combination with the location of the T4-free less than zero percentile, and T3-free less than the 25th percentile make a judgment on decompensated hypothyroidism.

Claims

A method for determining the clinical variant of euthyroidism and hypothyroidism by comparing laboratory blood analysis data with reference values of TSH, T4-free and T3-free indicators, characterized in that the ratio of laboratory analysis data to percentiles of reference values of indicators is estimated so that when the TSH value is from zero to the 25th percentile, in combination with finding T4-free and T3-free between the 25th and 75th percentiles, they make an opinion on the euthyroidism of the optimum, with the value TSH from the 25th to the 50th percentile, in combination with the location of the T4-free and T3-free within the reference boundaries, make a judgment about pre-stress euthyroidism, when the TSH value is from the 50th to the 100th percentile, in combination with finding T4-free and T3-free within the reference boundaries makes a judgment about stress euthyroidism, with an increase in the TSH value of more than 100th percentile, in combination with the location of T4-free and T3-free between the 25th and 75th percentiles of the reference interval judgment of compensated hypothyroidism, with an increase in TSH values above the 100th percentile, in combination with the location of T4-free from zero to 25th percentile, and T3-free from 25th to 75th percentile make a judgment on subcompensated hypothyroidism, with increasing value TSH over 100 percentile, in combination with the location of the T4-free less than zero percentile, and T3-free less than the 25th percentile make a judgment on decompensated hypothyroidism.