RU2013140122A - DIAGNOSTIC METHOD OF BREAST CANCER - Google Patents
DIAGNOSTIC METHOD OF BREAST CANCER Download PDFInfo
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- RU2013140122A RU2013140122A RU2013140122/15A RU2013140122A RU2013140122A RU 2013140122 A RU2013140122 A RU 2013140122A RU 2013140122/15 A RU2013140122/15 A RU 2013140122/15A RU 2013140122 A RU2013140122 A RU 2013140122A RU 2013140122 A RU2013140122 A RU 2013140122A
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- RU
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- breast cancer
- pdlim4
- level
- diagnostic method
- ril
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Способ диагностики субтипа рака молочной железы, характеризующийся тем, что определяют уровень экспрессии PDLIM4/RIL в образце опухолевой ткани пациента с помощью технологии секвенирования следующего поколения NGS или методами Нозерн-гибридизации и ПЦР в реальном времени, и при снижении экспрессии PDLIM4/RIL более чем в два раза в сравнении с его уровнем в нормальных тканях, диагностируют злокачественный процесс - рак молочной железы по PIL-негативному типу.A method for diagnosing a breast cancer subtype, characterized in that the level of PDLIM4 / RIL expression in a patient’s tumor tissue sample is determined using next-generation NGS sequencing technology or real-time Northern hybridization and PCR methods, and with a decrease in PDLIM4 / RIL expression by more than two times in comparison with its level in normal tissues, they diagnose a malignant process - breast cancer by PIL-negative type.
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RU2013140122/15A RU2547583C2 (en) | 2013-08-30 | 2013-08-30 | Diagnostic technique for breast cancer |
Applications Claiming Priority (1)
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RU2013140122/15A RU2547583C2 (en) | 2013-08-30 | 2013-08-30 | Diagnostic technique for breast cancer |
Publications (2)
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RU2013140122A true RU2013140122A (en) | 2015-03-10 |
RU2547583C2 RU2547583C2 (en) | 2015-04-10 |
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RU2013140122/15A RU2547583C2 (en) | 2013-08-30 | 2013-08-30 | Diagnostic technique for breast cancer |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2619739C2 (en) * | 2012-05-30 | 2017-05-17 | Федеральное государственное бюджетное учреждение "Российский научный центр рентгенорадиологии" Министерства здравоохранения российской федерации (ФГБУ "РНЦРР" Минздрава России) | Method for diagnosis and prediction in case of breast hyperproliferative diseases |
RU2612139C1 (en) * | 2015-12-29 | 2017-03-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Set of synthetic oligonucleotides for determination of levels of gene pdlim4 expression |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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ITPD20110201A1 (en) * | 2011-06-16 | 2012-12-17 | Univ Degli Studi Trieste | METHOD FOR THE PROGNOSIS OF BREAST CANCER BASED ON THE EXPRESSION OF ENZYME PROLYL ISOMERARASE PIN1 IN COMBINATION WITH MUTATIONS OF THE GENE TP53 |
RU2486518C1 (en) * | 2012-01-10 | 2013-06-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт онкологии Сибирского отделения Российской академии медицинских наук (НИИ онкологии СО РАМН) | Method for prediction of onset of local recurrences in surgical scars in unicentric invasive duct breast cancer in patients with preserved menstrual function |
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- 2013-08-30 RU RU2013140122/15A patent/RU2547583C2/en active
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RU2547583C2 (en) | 2015-04-10 |
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