RU2012108237A - METHOD FOR PREDICTING HEALING EFFECTIVENESS OF TROPHIC ULCERS OF LOWER EXTREMITIES - Google Patents

METHOD FOR PREDICTING HEALING EFFECTIVENESS OF TROPHIC ULCERS OF LOWER EXTREMITIES Download PDF

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RU2012108237A
RU2012108237A RU2012108237/14A RU2012108237A RU2012108237A RU 2012108237 A RU2012108237 A RU 2012108237A RU 2012108237/14 A RU2012108237/14 A RU 2012108237/14A RU 2012108237 A RU2012108237 A RU 2012108237A RU 2012108237 A RU2012108237 A RU 2012108237A
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RU
Russia
Prior art keywords
trophic ulcers
lower extremities
predicting
expression
bcl
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RU2012108237/14A
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Russian (ru)
Inventor
Александр Абрамович Стадников
Ольга Борисовна Нузова
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Государственное бюджетное образовательное учреждение высшего профессионального образования "Оренбургская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО ОрГМА Минздравсоцразвития России)
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Application filed by Государственное бюджетное образовательное учреждение высшего профессионального образования "Оренбургская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО ОрГМА Минздравсоцразвития России) filed Critical Государственное бюджетное образовательное учреждение высшего профессионального образования "Оренбургская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО ОрГМА Минздравсоцразвития России)
Priority to RU2012108237/14A priority Critical patent/RU2012108237A/en
Publication of RU2012108237A publication Critical patent/RU2012108237A/en

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Abstract

Способ прогнозирования эффективности заживления трофических язв нижних конечностей путем исследования эксцизивного биоптата, отличающийся тем, что на седьмой день лечения осуществляют забор для идентификации клеток с экспрессии синтеза проапоптотического протеина р53 и антиапоптотического протеина bcl-2 у фибробластов и при показаниях экспрессии синтеза протеинов р53 - (9,2±0,92)%и ниже, а bcl-2 - (3,7±0,07)%и выше судят об эффективности заживления трофических язв.A method for predicting the healing efficiency of trophic ulcers of the lower extremities by examining an excisive biopsy specimen, characterized in that on the seventh day of treatment, a sampling is performed to identify cells with expression of the synthesis of pro-apoptotic protein p53 and anti-apoptotic protein bcl-2 in fibroblasts and for indications of expression of protein synthesis p53 - (9 , 2 ± 0.92)% and lower, and bcl-2 - (3.7 ± 0.07)% and higher judge the effectiveness of healing of trophic ulcers.

Claims (1)

Способ прогнозирования эффективности заживления трофических язв нижних конечностей путем исследования эксцизивного биоптата, отличающийся тем, что на седьмой день лечения осуществляют забор для идентификации клеток с экспрессии синтеза проапоптотического протеина р53 и антиапоптотического протеина bcl-2 у фибробластов и при показаниях экспрессии синтеза протеинов р53 - (9,2±0,92)%0 и ниже, а bcl-2 - (3,7±0,07)%0 и выше судят об эффективности заживления трофических язв. A method for predicting the healing efficiency of trophic ulcers of the lower extremities by examining an excisive biopsy specimen, characterized in that on the seventh day of treatment, a sampling is performed to identify cells with expression of the synthesis of pro-apoptotic protein p53 and anti-apoptotic protein bcl-2 in fibroblasts and for indications of expression of protein synthesis p53 - (9 , 2 ± 0.92)% 0 and lower, and bcl-2 - (3.7 ± 0.07)% 0 and higher judge the effectiveness of the healing of trophic ulcers.
RU2012108237/14A 2012-03-05 2012-03-05 METHOD FOR PREDICTING HEALING EFFECTIVENESS OF TROPHIC ULCERS OF LOWER EXTREMITIES RU2012108237A (en)

Priority Applications (1)

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RU2012108237/14A RU2012108237A (en) 2012-03-05 2012-03-05 METHOD FOR PREDICTING HEALING EFFECTIVENESS OF TROPHIC ULCERS OF LOWER EXTREMITIES

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RU2012108237/14A RU2012108237A (en) 2012-03-05 2012-03-05 METHOD FOR PREDICTING HEALING EFFECTIVENESS OF TROPHIC ULCERS OF LOWER EXTREMITIES

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RU2012108237A true RU2012108237A (en) 2013-12-10

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