RU2011113645A - METHOD FOR PREDICTING THE RESULTS OF ANTI-VIRAL THERAPY OF CHRONIC HEPATITIS B - Google Patents
METHOD FOR PREDICTING THE RESULTS OF ANTI-VIRAL THERAPY OF CHRONIC HEPATITIS B Download PDFInfo
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- RU2011113645A RU2011113645A RU2011113645/15A RU2011113645A RU2011113645A RU 2011113645 A RU2011113645 A RU 2011113645A RU 2011113645/15 A RU2011113645/15 A RU 2011113645/15A RU 2011113645 A RU2011113645 A RU 2011113645A RU 2011113645 A RU2011113645 A RU 2011113645A
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- chronic hepatitis
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Abstract
Способ прогнозирования исходов противовирусной терапии хронического гепатита В путем иммунологического и биохимического исследования крови, отличающийся тем, что определяют следующие показатели крови: количество лейкоцитов, относительное количество лимфоцитов, относительное количество CD3+ лимфоцитов, абсолютное количество CD4+ лимфоцитов, относительное количество CD8+ лимфоцитов, абсолютное количество CD8+ лимфоцитов, содержание общего билирубина, вычисляют значение дискриминантной функции по формуле ! DF=0,7180x1+0,0915х2+0,3596х3+10,7331х4+0,1922х5+7,3993х6-0,1352х7, ! где DF - значение дискриминантной функции; ! х1 - количество лейкоцитов, клеток ×109 /л; ! х2 - относительное количество лимфоцитов, %; ! х3 - относительное количество CD3+ лимфоцитов, %; ! х4 - абсолютное количество CD4+ лимфоцитов, клеток ×109 /л; ! х5 - относительное количество CD8+ лимфоцитов, %; ! х6 - абсолютное количество CD8+ лимфоцитов, клеток ×109 /л; ! х7 - содержание общего билирубина, мкмоль/л, ! по которому с помощью номограммы определения вероятностей исходов противовирусной терапии у пациентов с хроническим гепатитом В, содержащейся в описании, определяют вероятности рецидива и стойкого ответа после стандартной противовирусной терапии хронического гепатита В. A method for predicting the outcome of antiviral therapy of chronic hepatitis B by immunological and biochemical blood tests, characterized in that the following blood parameters are determined: white blood cell count, relative lymphocyte count, relative CD3 + lymphocyte count, absolute CD4 + lymphocyte count, relative CD8 + lymphocyte count, absolute CD8 + lymphocyte count , the content of total bilirubin, calculate the value of the discriminant function according to the formula! DF = 0.7180x1 + 0.0915x2 + 0.3596x3 + 10.7331x4 + 0.1922x5 + 7.3993x6-0.1352x7! where DF is the value of the discriminant function; ! x1 - the number of leukocytes, cells × 109 / l; ! x2 is the relative number of lymphocytes,%; ! x3 is the relative number of CD3 + lymphocytes,%; ! x4 - the absolute number of CD4 + lymphocytes, cells × 109 / l; ! x5 - relative number of CD8 + lymphocytes,%; ! x6 - the absolute number of CD8 + lymphocytes, cells × 109 / l; ! x7 - the content of total bilirubin, µmol / l,! according to which, using the nomogram for determining the probabilities of antiviral therapy outcomes in patients with chronic hepatitis B, contained in the description, the probabilities of relapse and persistent response after standard antiviral therapy of chronic hepatitis B are determined
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RU2011113645/15A RU2469327C1 (en) | 2011-04-07 | 2011-04-07 | Method for prediction of clinical outcomes of antiviral therapy of chronic hepatitis b |
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RU2011113645/15A RU2469327C1 (en) | 2011-04-07 | 2011-04-07 | Method for prediction of clinical outcomes of antiviral therapy of chronic hepatitis b |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111579779A (en) * | 2020-05-09 | 2020-08-25 | 中山大学附属第一医院 | Marker for evaluating immune cell function of hepatitis B patient and application thereof |
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RU2560673C1 (en) * | 2014-02-19 | 2015-08-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for assessing effectiveness of therapy of children with chronic viral hepatitis b |
RU2571493C2 (en) * | 2014-04-18 | 2015-12-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for prediction of antiretroviral therapy outcomes in chronic hepatitis b |
RU2710264C1 (en) * | 2019-10-01 | 2019-12-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for prediction of lipid distress syndrome development in patients with stable virologic response to antiviral therapy of chronic hepatitis c |
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RU2200954C2 (en) * | 2001-01-09 | 2003-03-20 | Овсянникова Елена Георгиевна | Method of prognosis of chronic hepatitis b course specificity in patients with hemoblastosis |
RU2282194C1 (en) * | 2005-04-18 | 2006-08-20 | Кира Игоревна Чуйкова | Method of prognosing outputs of viral hepatites b and b+c |
RU2379689C1 (en) * | 2008-06-16 | 2010-01-20 | ФГУ "Нижегородский НИИ детской гастроэнтерологии Росмедтехнологий" | Method for prediction of if therapy effectiveness for viral hepatitis in children |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111579779A (en) * | 2020-05-09 | 2020-08-25 | 中山大学附属第一医院 | Marker for evaluating immune cell function of hepatitis B patient and application thereof |
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