RU2010145995A - MEANS OF REDUCING MAMMAL ANXIETY, METHOD OF REDUCING ANXIETY, APPLICATION OF DELTA-OPIOID RECEPTOR ANTAGONISTS THAT DO NOT APPLY THROUGH HEMATO-ENCEPHALIC BARRIEROUS - Google Patents
MEANS OF REDUCING MAMMAL ANXIETY, METHOD OF REDUCING ANXIETY, APPLICATION OF DELTA-OPIOID RECEPTOR ANTAGONISTS THAT DO NOT APPLY THROUGH HEMATO-ENCEPHALIC BARRIEROUS Download PDFInfo
- Publication number
- RU2010145995A RU2010145995A RU2010145995/15A RU2010145995A RU2010145995A RU 2010145995 A RU2010145995 A RU 2010145995A RU 2010145995/15 A RU2010145995/15 A RU 2010145995/15A RU 2010145995 A RU2010145995 A RU 2010145995A RU 2010145995 A RU2010145995 A RU 2010145995A
- Authority
- RU
- Russia
- Prior art keywords
- anxiety
- reducing
- delta
- mammal
- opioid receptor
- Prior art date
Links
Abstract
1. Средство снижения уровня тревожности млекопитающего, характеризующееся тем, что оно содержит антагонист дельта-опиоидных рецепторов, не проникающий через гемато-энцефалический барьер. ! 2. Способ снижения уровня тревожности, характеризующийся тем, что млекопитающему перорально вводят антагонист дельта-опиоидных рецепторов, не проникающий через гемато-энцефалический барьер. ! 3. Применение антагонистов дельта-опиоидных рецепторов, не проникающих через гемато-энцефалический барьер, для приготовления средства снижения уровня тревожности млекопитающего. 1. A means of reducing the anxiety level of a mammal, characterized in that it contains a delta-opioid receptor antagonist that does not penetrate the blood-brain barrier. ! 2. A method of reducing anxiety, characterized in that the mammal is orally administered a delta-opioid receptor antagonist that does not cross the blood-brain barrier. ! 3. The use of antagonists of delta opioid receptors that do not penetrate the blood-brain barrier to prepare a means of reducing the level of anxiety in a mammal.
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2010145995/15A RU2470661C2 (en) | 2010-11-11 | 2010-11-11 | Method for reducing mammalian anxiety level, method for reducing anxiety level, use of delta-opioid receptor antagonists not penetrating through brain-blood barrier for preparing anxiolytic agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2010145995/15A RU2470661C2 (en) | 2010-11-11 | 2010-11-11 | Method for reducing mammalian anxiety level, method for reducing anxiety level, use of delta-opioid receptor antagonists not penetrating through brain-blood barrier for preparing anxiolytic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2010145995A true RU2010145995A (en) | 2012-10-27 |
RU2470661C2 RU2470661C2 (en) | 2012-12-27 |
Family
ID=47146812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2010145995/15A RU2470661C2 (en) | 2010-11-11 | 2010-11-11 | Method for reducing mammalian anxiety level, method for reducing anxiety level, use of delta-opioid receptor antagonists not penetrating through brain-blood barrier for preparing anxiolytic agents |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2470661C2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2580311C1 (en) * | 2014-12-26 | 2016-04-10 | Федеральное государственное бюджетное учреждение науки Институт молекулярной генетики Российской академии наук | Antianxiety drugs and pharmaceutical compositions with anxiolytic effects |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2161500C1 (en) * | 1999-07-06 | 2001-01-10 | Институт молекулярной генетики РАН | Heptapeptide with adaptogenic and anxiolytic activity |
RU2196579C2 (en) * | 2001-02-08 | 2003-01-20 | Амурская государственная медицинская академия | Method for decreasing level of anxiety in laboratory animals during an experiment |
RU2007134356A (en) * | 2007-09-14 | 2009-03-20 | ГОСУДАРСТВЕННОЕ ОБРАЗОВАТЕЛЬНОЕ УЧРЕЖДЕНИЕ ВЫСШЕГО ПРОФЕССИОНАЛЬНОГО ОБРАЗОВАНИЯ АМУРСКАЯ ГОСУДАРСТВЕННАЯ МЕДИЦИНСКАЯ АКАДЕМИЯ Росздрава (RU) | METHOD FOR REDUCING ANXIETY LEVEL IN EXPERIMENT |
RU2398761C2 (en) * | 2008-06-16 | 2010-09-10 | Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) | Anxiolytics |
-
2010
- 2010-11-11 RU RU2010145995/15A patent/RU2470661C2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2470661C2 (en) | 2012-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR20C1022I2 (en) | DOSAGE OF AN S1P RECEPTOR AGONIST | |
EA201290355A1 (en) | SPYROPYPERIDINE CONNECTIONS AS ANTAGONISTS OF ORL-1 RECEPTOR | |
EA201390977A1 (en) | COMBINATION OF OPIOID RECEPTOR AGONIST AND OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OF PARKINSON'S Disease | |
PE20141171A1 (en) | ORAL PHARMACEUTICAL DOSAGE FORM RESISTANT TO ALTERATION INCLUDING OPIOID AGONIST AND OPIOID ANTAGONIST | |
BRPI1008060A2 (en) | S1p5 receptor agonists and antagonists, and methods of use thereof. | |
HK1188211A1 (en) | Cxcr4 receptor antagonists cxcr4 | |
CR20140182A (en) | NEW CYCLOHEXYLAMINE DERIVATIVES THAT HAVE ACTIVITY AS ADRENERGIC B2 AGONISTS AND AS M3 MUSCARINIC ANTAGONISTS | |
ECSP12012213A (en) | NEW CYCLOHEXYLAMINE DERIVATIVES THAT HAVE ACTIVITY AS ADRENERGIC AGONISTS? 2 AND AS M3 MUSCARINIC ANTAGONISTS | |
AU2011234398A8 (en) | Novel NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders | |
BR112014014547A2 (en) | e-selectin antagonist compounds, compositions and methods of use | |
SMT201600164B (en) | NEW N-ACYL-5, 6, 7, (8-SODSTITUTED) -TETRAIDRO- [1, 2, 4] TRIAZOL [4, 3-A] CHIRAL PIRAZINES AS SELECTIVE ANTAGONISTS OF THE NK-3 RECEPTOR, PHARMACEUTICAL COMPOSITION, AND METHODS FOR USE IN DISORDERS MEDIATED BY NK-3 RECEPTOR | |
ECSP14013340A (en) | NEW CYCLOHEXYLAMINE DERIVATIVES THAT HAVE ACTIVITY AS ADRENERGIC AGONISTS? 2 AND AS M3 MUSCARINIC ANTAGONISTS | |
HK1187045A1 (en) | Buprenorphine analogs as opioid receptor agonists and or antagonists | |
MY160665A (en) | Spiropiperidine compounds as orl-1 receptor antagonists | |
SMT201700064B (en) | D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE | |
EA201391662A1 (en) | CONNECTIONS WITH THE ACTIVITY OF ANTAGONISTS OF MUSCARINE RECEPTORS AND AGONISTS OF THE ADRENERGIC RECEPTOR BETA2 | |
DK2252581T3 (en) | CAPE-SELECTIVE OPIOID RECEPTOR ANTAGONIST | |
MA32301B1 (en) | 1-aryl-3-amine-coccyberazole as a sigma bond increases the analgesic effect of opioids by reducing dependence on the latter | |
DK3312169T3 (en) | 5-HT3 RECEPTOR ANTAGONISTS | |
EA201491153A1 (en) | COMPOSITIONS OF BUPRENORPHINE AND ANTAGONISTS OF μ-OPIOID RECEPTORS | |
UY35776A (en) | ? ANTAGONISTAS RECEPTOR EP3 PROSTAGLANDINA ?. | |
CL2012000263A1 (en) | Compounds derived from spirocyclic amides, b-adrenoreceptor agonist and muscarinic antagonist; useful in the treatment of inflammatory diseases, such as COPD. | |
CL2013000502A1 (en) | Compounds derived from-2- (1- (2 (2-carbonyl-ethyl) benzyl) pyrrolidin-2-yl) -n-alkyloxazole-4-carboxamide; use in the treatment of diseases involved with the anti-inflammatory response in prostaglandin receptors. | |
EA201390653A1 (en) | AA ANTAGONISTS AS AMPLIFIERS OF COGNITIVE AND MOTOR FUNCTIONS | |
FR2965612B1 (en) | DEVICE FOR MEASURING THE EVOLUTION OF A CRACK, IN PARTICULAR A BUILDING WALL |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20181112 |