RU2009125254A - METHOD FOR INTRODUCING LIQUID SUBSTANCE IN MICROCapsules AND DEVICE FOR ITS IMPLEMENTATION - Google Patents
METHOD FOR INTRODUCING LIQUID SUBSTANCE IN MICROCapsules AND DEVICE FOR ITS IMPLEMENTATION Download PDFInfo
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- RU2009125254A RU2009125254A RU2009125254/14A RU2009125254A RU2009125254A RU 2009125254 A RU2009125254 A RU 2009125254A RU 2009125254/14 A RU2009125254/14 A RU 2009125254/14A RU 2009125254 A RU2009125254 A RU 2009125254A RU 2009125254 A RU2009125254 A RU 2009125254A
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- Russia
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- microcapsules
- plate
- microchannel
- microchannel plate
- liquid substance
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- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
1. Способ введения жидкого вещества в микрокапсулы с помощью решетки микроигл и ответной пластины-держателя, отличающийся тем, что микрокапсулы подают на вход в микроканальную пластину, при этом диаметр каналов ее меньше размера микрокапсул, которые задерживаются на входе в микроканальную пластину после отвода через нее жидкости, а затем перемещают решетку микроигл до прокалывания оболочки микрокапсул и вводят жидкое вещество, после чего удаляют заполненные микрокапсулы, изменяя направление течения потока жидкости сквозь микроканальную пластину на обратное. ! 2. Устройство для ввода жидкого вещества в микрокапсулы, содержащее решетку с микроиглами, сообщающимися с резервуаром вводимого вещества и установленными соосно с пластиной-держателем с возможностью перемещения навстречу друг другу, отличающееся тем, что пластина-держатель выполнена в виде микроканальной пластины и установлена вместе с решеткой микроигл в канале с поршневым узлом и клапанами, обеспечивающими необходимое направление течения жидкости через микроканальную пластину, при этом каналы в микроканальной пластине выполнены с диаметром, меньшим размера микрокапсул, причем движение решетки микроигл навстречу микроканальной пластине осуществляется до прокалывания оболочки микрокапсул. 1. The method of introducing a liquid substance into the microcapsules using a microneedle array and a counter holder plate, characterized in that the microcapsules are fed into the microchannel plate, while the diameter of the channels is less than the size of the microcapsules that are delayed at the entrance to the microchannel plate after removal through it liquids, and then the microneedle array is moved until the shell of the microcapsules is pierced and a liquid substance is introduced, after which the filled microcapsules are removed, changing the direction of the flow of the liquid through the microchannel th plate on the contrary. ! 2. A device for introducing a liquid substance into microcapsules, containing a lattice with microneedles communicating with the reservoir of the introduced substance and mounted coaxially with the holder plate with the possibility of moving towards each other, characterized in that the holder plate is made in the form of a microchannel plate and installed together with a microneedle array in a channel with a piston assembly and valves providing the necessary direction of fluid flow through the microchannel plate, while the channels in the microchannel plate are made diameter smaller than the size of the microcapsules, wherein the lattice microneedles movement toward the microchannel plate is carried out before the piercing shell of the microcapsules.
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2009125254/14A RU2414255C1 (en) | 2009-07-01 | 2009-07-01 | Method of liquid substance introduction in microcapsules and related device for implementation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2009125254/14A RU2414255C1 (en) | 2009-07-01 | 2009-07-01 | Method of liquid substance introduction in microcapsules and related device for implementation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2009125254A true RU2009125254A (en) | 2011-01-10 |
RU2414255C1 RU2414255C1 (en) | 2011-03-20 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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RU2009125254/14A RU2414255C1 (en) | 2009-07-01 | 2009-07-01 | Method of liquid substance introduction in microcapsules and related device for implementation thereof |
Country Status (1)
Country | Link |
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RU (1) | RU2414255C1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
EP2566501B1 (en) | 2010-05-04 | 2019-03-13 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
CA2896188C (en) | 2012-12-21 | 2021-02-23 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
ES2921481T3 (en) | 2013-03-12 | 2022-08-26 | Corium Inc | Microprojection applicators |
AU2014237279B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
EP2968751B1 (en) | 2013-03-15 | 2022-11-30 | Corium, Inc. | Multiple impact microprojection applicators |
BR112015022432B1 (en) * | 2013-03-15 | 2022-02-15 | Corium, Inc | MICROSTRUCTURE ARRANGEMENT, METHOD FOR MANUFACTURING IT AND LIQUID FORMULATION TO FORM DISSOLUTION MICROSTRUCTURES |
AU2014233695A1 (en) | 2013-03-15 | 2015-10-01 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
WO2016036866A1 (en) | 2014-09-04 | 2016-03-10 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
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2009
- 2009-07-01 RU RU2009125254/14A patent/RU2414255C1/en active
Also Published As
Publication number | Publication date |
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RU2414255C1 (en) | 2011-03-20 |
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