RU2008141076A - APPLICATION OF THERAPEUTIC HUMAN ALBUMIN FOR THE PRODUCTION OF A MEDICINE FOR THE TREATMENT OF PATIENTS AFFECTING COGNITIVE DISORDERS - Google Patents

APPLICATION OF THERAPEUTIC HUMAN ALBUMIN FOR THE PRODUCTION OF A MEDICINE FOR THE TREATMENT OF PATIENTS AFFECTING COGNITIVE DISORDERS Download PDF

Info

Publication number
RU2008141076A
RU2008141076A RU2008141076/14A RU2008141076A RU2008141076A RU 2008141076 A RU2008141076 A RU 2008141076A RU 2008141076/14 A RU2008141076/14 A RU 2008141076/14A RU 2008141076 A RU2008141076 A RU 2008141076A RU 2008141076 A RU2008141076 A RU 2008141076A
Authority
RU
Russia
Prior art keywords
use according
albumin
treatment
cognitive disorders
human albumin
Prior art date
Application number
RU2008141076/14A
Other languages
Russian (ru)
Other versions
RU2414925C2 (en
Inventor
РОУРА Виктор ГРИФОЛЬС (ES)
РОУРА Виктор ГРИФОЛЬС
Original Assignee
Грифольс, С.А. (Es)
Грифольс, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Грифольс, С.А. (Es), Грифольс, С.А. filed Critical Грифольс, С.А. (Es)
Publication of RU2008141076A publication Critical patent/RU2008141076A/en
Application granted granted Critical
Publication of RU2414925C2 publication Critical patent/RU2414925C2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

1. Применение человеческого альбумина для изготовления лекарственного средства для лечения пациентов, страдающих когнитивными расстройствами или обладающих риском их развития, независимо от содержания Аβ в крови пациента. ! 2. Применение по п.1, при котором это лекарственное средство находится в форме раствора для плазмафильтрации. ! 3. Применение по п.1, при котором это лекарственное средство находится в форме раствора для внутривенного применения. ! 4. Применение по п.1, при котором альбумин исходно имеет концентрацию от 4% (мас./об.) до 25% (мас./об.). ! 5. Применение по п.4, при котором применяемый альбумин имеет концентрацию от 4,5% (мас./об.) до 5,5% (мас./об.). ! 6. Применение по п.1, при котором применяемый альбумин обладает лучшей связывающей способностью по сравнению с терапевтическим препаратом альбумина, изготовленным в соответствии с Европейской Фармакопеей. ! 7. Применение по любому из пп.1-6, при котором когнитивное расстройство представляет собой болезнь Альцгеймера. 1. The use of human albumin for the manufacture of a medicament for the treatment of patients suffering from cognitive disorders or at risk of their development, regardless of the content of Aβ in the blood of the patient. ! 2. The use according to claim 1, wherein the drug is in the form of a plasma filtration solution. ! 3. The use according to claim 1, in which this drug is in the form of a solution for intravenous use. ! 4. The use according to claim 1, wherein the albumin initially has a concentration of from 4% (w / v) to 25% (w / v). ! 5. The use according to claim 4, in which the used albumin has a concentration of from 4.5% (wt./about.) To 5.5% (wt./about.). ! 6. The use according to claim 1, in which the used albumin has better binding ability compared to a therapeutic albumin preparation made in accordance with the European Pharmacopoeia. ! 7. The use according to any one of claims 1 to 6, in which the cognitive disorder is Alzheimer's disease.

Claims (7)

1. Применение человеческого альбумина для изготовления лекарственного средства для лечения пациентов, страдающих когнитивными расстройствами или обладающих риском их развития, независимо от содержания Аβ в крови пациента.1. The use of human albumin for the manufacture of a medicament for the treatment of patients suffering from cognitive disorders or at risk of their development, regardless of the content of Aβ in the blood of the patient. 2. Применение по п.1, при котором это лекарственное средство находится в форме раствора для плазмафильтрации.2. The use according to claim 1, wherein the drug is in the form of a plasma filtration solution. 3. Применение по п.1, при котором это лекарственное средство находится в форме раствора для внутривенного применения.3. The use according to claim 1, in which this drug is in the form of a solution for intravenous use. 4. Применение по п.1, при котором альбумин исходно имеет концентрацию от 4% (мас./об.) до 25% (мас./об.).4. The use according to claim 1, wherein the albumin initially has a concentration of from 4% (w / v) to 25% (w / v). 5. Применение по п.4, при котором применяемый альбумин имеет концентрацию от 4,5% (мас./об.) до 5,5% (мас./об.).5. The use according to claim 4, in which the used albumin has a concentration of from 4.5% (wt./about.) To 5.5% (wt./about.). 6. Применение по п.1, при котором применяемый альбумин обладает лучшей связывающей способностью по сравнению с терапевтическим препаратом альбумина, изготовленным в соответствии с Европейской Фармакопеей.6. The use according to claim 1, in which the used albumin has a better binding ability compared to a therapeutic albumin preparation made in accordance with the European Pharmacopoeia. 7. Применение по любому из пп.1-6, при котором когнитивное расстройство представляет собой болезнь Альцгеймера. 7. The use according to any one of claims 1 to 6, in which the cognitive disorder is Alzheimer's disease.
RU2008141076/15A 2007-10-26 2008-10-17 Application of therapeutic human albumin for preparing drug for treating patients suffering cognitive disorders RU2414925C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200702831 2007-10-26
ES200702831A ES2332846B1 (en) 2007-10-26 2007-10-26 USE OF THERAPEUTIC HUMAN ALBUMIN FOR THE PREPARATION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF PATIENTS AFFECTED BY COGNITIVE DISORDERS.

Publications (2)

Publication Number Publication Date
RU2008141076A true RU2008141076A (en) 2010-04-27
RU2414925C2 RU2414925C2 (en) 2011-03-27

Family

ID=40583637

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008141076/15A RU2414925C2 (en) 2007-10-26 2008-10-17 Application of therapeutic human albumin for preparing drug for treating patients suffering cognitive disorders

Country Status (17)

Country Link
US (1) US7851446B2 (en)
EP (1) EP2111868B1 (en)
JP (1) JP5437619B2 (en)
CN (1) CN101417123B (en)
AR (1) AR068901A1 (en)
AU (1) AU2008233025B8 (en)
BR (1) BRPI0804623B8 (en)
CA (1) CA2641830C (en)
CL (1) CL2008003133A1 (en)
ES (2) ES2332846B1 (en)
HK (1) HK1126689A1 (en)
MX (1) MX2008013635A (en)
NZ (1) NZ572131A (en)
PL (1) PL2111868T3 (en)
PT (1) PT2111868E (en)
RU (1) RU2414925C2 (en)
UY (1) UY31418A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10112000B2 (en) 2010-07-08 2018-10-30 Asahi Kasei Medical Co., Ltd. Method for reducing amyloid beta concentration in blood
CA3033051A1 (en) * 2016-08-18 2018-02-22 Alkahest, Inc. Blood plasma fractions as a treatment for aging-associated cognitive disorders
US10525107B2 (en) 2016-08-18 2020-01-07 Alkahest, Inc. Blood plasma fractions as a treatment for aging-associated cognitive disorders
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
MA48480A (en) 2017-04-26 2020-03-04 Alkahest Inc DOSAGE SCHEDULE FOR THE TREATMENT OF COGNITIVE AND MOTOR DEFICIENCIES WITH BLOOD PLASMA AND BLOOD PLASMA PRODUCTS
EP3823636A4 (en) * 2018-07-20 2022-04-13 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
EP3643319A1 (en) * 2018-10-25 2020-04-29 Grifols Worldwide Operations Limited Use of low volume plasma exchange for the treatment of alzheimer's disease in early and middle stages
EP3870190A4 (en) 2018-10-26 2022-09-07 Alkahest, Inc. Use of plasma and plasma fractions for improvement of pain, wound healing, and postoperative recovery
UY39742A (en) * 2021-04-30 2022-11-30 Grifols Worldwide Operations Ltd USE OF THERAPEUTIC PLASMA EXCHANGE AND LOW VOLUME PLASMA EXCHANGE FOR TREATMENT *

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3612137A1 (en) * 1986-04-10 1987-10-15 Biotest Pharma Gmbh STERILE PLASMA REPLACEMENT
US5112298A (en) 1990-06-25 1992-05-12 Baxter International Inc. Apheresis method and device
US5178603A (en) 1990-07-24 1993-01-12 Baxter International, Inc. Blood extraction and reinfusion flow control system and method
US6627151B1 (en) * 1997-06-13 2003-09-30 Helmut Borberg Method for treatment diseases associated with a deterioration of the macrocirculation, microcirculation and organ perfusion
EP1290451B1 (en) 2000-05-23 2005-12-07 University Of Southern California Diagnosis of alzheimer's disease using ldl receptor protein-1
WO2002078670A1 (en) * 2001-03-02 2002-10-10 Neuron Therapeutics, Inc. Neuroprotectants formulations and methods
AU2002366355A1 (en) 2001-12-17 2003-06-30 New York State Office Of Mental Health SEQUESTRATION OF ABeta IN THE PERIPHERY IN THE ABSENCE OF IMMUNOMODULATING AGENT AS A THERAPEUTIC APPROACH FOR THE TREATMENT OR PREVENTION OF BETA-AMYLOID RELATED DISEASES
BR0315008A (en) 2002-10-04 2005-08-09 Prana Biotechnology Ltd Neurologically Active Compounds
WO2004056318A2 (en) * 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
ES2285427T3 (en) 2003-02-13 2007-11-16 Octapharma Ag PROCEDURE FOR PREPARATION OF AN ALBUMIN SOLUTION.
US20050042284A1 (en) 2003-07-11 2005-02-24 Myriad Genetics, Incorporated Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease
AT413336B (en) * 2003-09-12 2006-02-15 Mattner Frank Dr APHERESIS DEVICE
US20050182044A1 (en) 2004-02-17 2005-08-18 Bruinsma Gosse B. Combinatorial therapy with an acetylcholinesterase inhibitor and (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate
AT500483B1 (en) 2004-07-13 2006-01-15 Mattner Frank Dr Kit for prevention or treatment of Alzheimer's disease comprises means for inducing sequestration of amyloid beta in plasma and apheresis apparatus which exhibits an amyloid beta precursor protein receptor
US7436304B1 (en) 2005-07-19 2008-10-14 Visible Assets, Inc Evidence tracking

Also Published As

Publication number Publication date
BRPI0804623A2 (en) 2009-06-30
AU2008233025B2 (en) 2013-06-27
CN101417123B (en) 2012-06-27
BRPI0804623B8 (en) 2021-05-25
NZ572131A (en) 2010-06-25
CA2641830C (en) 2013-07-16
JP2009108059A (en) 2009-05-21
US20090111740A1 (en) 2009-04-30
BRPI0804623B1 (en) 2020-02-11
UY31418A1 (en) 2009-05-29
RU2414925C2 (en) 2011-03-27
CL2008003133A1 (en) 2009-08-07
PT2111868E (en) 2013-10-17
ES2428698T3 (en) 2013-11-08
AU2008233025B8 (en) 2013-07-25
AU2008233025A1 (en) 2009-05-14
ES2332846B1 (en) 2010-07-08
EP2111868B1 (en) 2013-08-21
PL2111868T3 (en) 2014-01-31
AR068901A1 (en) 2009-12-16
US7851446B2 (en) 2010-12-14
CA2641830A1 (en) 2009-04-26
EP2111868A1 (en) 2009-10-28
CN101417123A (en) 2009-04-29
ES2332846A1 (en) 2010-02-12
JP5437619B2 (en) 2014-03-12
HK1126689A1 (en) 2009-09-11
MX2008013635A (en) 2009-05-11

Similar Documents

Publication Publication Date Title
RU2008141076A (en) APPLICATION OF THERAPEUTIC HUMAN ALBUMIN FOR THE PRODUCTION OF A MEDICINE FOR THE TREATMENT OF PATIENTS AFFECTING COGNITIVE DISORDERS
JP2022009125A5 (en)
Tang et al. Intranasal dexmedetomidine on stress hormones, inflammatory markers, and postoperative analgesia after functional endoscopic sinus surgery
RU2015134581A (en) NITROXIL DONORS WITH IMPROVED THERAPEUTIC INDEX
JP2011512856A5 (en)
EA200700214A1 (en) MEMANTINE AS AN ADDITIONAL THERAPY FOR ATYPICAL ANTIPSYCHOTIC REMEDIES IN PATIENTS WITH SCHIZOPHRENIA
RU2012108656A (en) APPLICATION OF 4-AMINOPYRIDINE TO IMPROVE CONDITION IN NEURO-COGNITIVE AND / OR NEUROPSYCHIATRIC DISORDERS IN PATIENTS WITH DEMILINIZING AND OTHER DISEASES OF THE NERVOUS SYSTEM
CY1115269T1 (en) USE OF COMPETITIVE OPTIONS FOR THE PREPARATION OF A MEDICINE IN THE THERAPEUTIC TREATMENT OF BUBBLE DISEASES
ATE366581T1 (en) APOPTOTIC BODY FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND OTHER NERVOUS DISEASES
RU2013112890A (en) THERAPEUTIC USE 1- [2- (2,4-DIMETHYLPHENYLSULFANIL) Phenyl] PIPERASINE
NO20061515L (en) Use of oxcarbazepine for the treatment of diabetic neurpathic pain and improvement of sleep
EA200900214A1 (en) PHARMACEUTICAL COMPOSITION OF RIFABUTIN FOR THE TREATMENT OF TUBERCULOSIS, THE WAY OF ITS OBTAINING AND THE METHOD OF TREATMENT
RU2006101061A (en) ASENAPINE FOR THE TREATMENT OF SCHIZOPHRENIA IN PATIENTS WITH OVERBODY WEIGHT OR PREPAREDNESS FOR OVERWEIGHT BODY
ES2668943T3 (en) Pharmaceutical composition to treat premature ejaculation and method of treatment of premature ejaculation
RU2572504C1 (en) Method of treating radial sialadenopathy
Ghimire et al. Propofol sedation during spinal anaesthesia-a dose finding study
Megha et al. Ayurvedic management of Pakshaghata (Cerebrovascular Accident): A case study
Kovosi et al. Administering medications for Parkinson disease on time
RU2549474C1 (en) Method for preanaesthetic medication preceding gynaecological surgeries under general anaesthesia
Winter et al. 0561 Solriamfetol Real World Experience Study: Safety, Efficacy, and Follow-Up for Patients with Obstructive Sleep Apnea in Germany
Almomani The effect of ketamine on blood pressure, heart rate, respiratory rate and intraocular pressure in patients undergoing ocular procedures
Ahuja A Comparitive Clinical Evaluation of Dexmedetomidine V/S Propofol in Patients Undergoing Extraction of Impacted Mandibular Third Molars
RU2021106142A (en) USE OF LOW-VOLUME PLASMAPHERESIS FOR THE TREATMENT OF EARLY AND MIDDLE STAGES OF ALZHEIMER'S DISEASE
Lamichhane et al. A Bipolar Lady with Sudden Neurological Complications
Tang Using lithium