RU2006103302A - MONOCLONAL ANTIBODY TO TYPE B INFLUENZA VIRUS AND DEVICE FOR IMMUNE ANALYSIS USING ANTIBODY - Google Patents

MONOCLONAL ANTIBODY TO TYPE B INFLUENZA VIRUS AND DEVICE FOR IMMUNE ANALYSIS USING ANTIBODY Download PDF

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Publication number
RU2006103302A
RU2006103302A RU2006103302/13A RU2006103302A RU2006103302A RU 2006103302 A RU2006103302 A RU 2006103302A RU 2006103302/13 A RU2006103302/13 A RU 2006103302/13A RU 2006103302 A RU2006103302 A RU 2006103302A RU 2006103302 A RU2006103302 A RU 2006103302A
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Russia
Prior art keywords
influenza
virus
antibody
zone
immobilized
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RU2006103302/13A
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Russian (ru)
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RU2366663C2 (en
Inventor
Джун-ичи АЗУМИ (JP)
Джун-ичи АЗУМИ
Такаши ЯМАДА (JP)
Такаши ЯМАДА
Томои ХОНДА (JP)
Томои ХОНДА
Нобуюуки ФУДЖИИ (JP)
Нобуюуки ФУДЖИИ
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Фуджирибайо Инк. (Jp)
Фуджирибайо Инк.
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Publication of RU2366663C2 publication Critical patent/RU2366663C2/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Claims (5)

1. Моноклональное антитело к вирусу гриппа типа В или его антигенсвязывающий фрагмент, которое вступает в реакцию антиген-антитело с нуклеопротеином вируса В гриппа, имеющим молекулярную массу от 60 кДа до 75 кДа, и практически не вступает в реакцию антиген-антитело с вирусом А гриппа.1. A monoclonal antibody to type B influenza virus or its antigen-binding fragment that reacts an antigen-antibody with a virus B nucleoprotein of influenza, having a molecular weight of 60 kDa to 75 kDa, and practically does not react antigen-antibody with influenza A virus . 2. Моноклональное антитело или его антигенсвязывающий фрагмент по п.1, отличающееся тем, что оно получено с помощью гибридомы FrB1-03, депонированной под инвентарным номером FERM ВР-10070, гибридомы FrB1-07, депонированной под инвентарным номером FERM ВР-10071, или гибридомы FVB2-16, депонированной под инвентарным номером FERM ВР-10069, которые были депонированы в Международном Депозитарии в соответствии с Будапештским Соглашением.2. The monoclonal antibody or its antigen binding fragment according to claim 1, characterized in that it is obtained using hybridoma FrB1-03 deposited under accession number FERM BP-10070, hybridoma FrB1-07 deposited under accession number FERM BP-10071, or hybridomas FVB2-16 deposited under inventory number FERM BP-10069, which were deposited with the International Depository in accordance with the Budapest Agreement. 3. Устройство для иммунологического анализа, содержащее зону меченого реагента, содержащую меченое мобильное антитело к вирусу В гриппа, зону нанесения образца, зону подачи проявителя, зону поглощения проявителя и зону детектирования вируса В гриппа, в которой антитело к вирусу В гриппа иммобилизовано на матриксе, причем зоны заданы на матриксе, при этом, по крайней мере, одно из следующих - меченое антитело к вирусу В гриппа и антитело к вирусу В гриппа, иммобилизованное в зоне детектирования - является моноклональным антителом по п.1 или 2.3. An immunological assay device comprising a labeled reagent zone containing a labeled mobile antibody for influenza B virus, a sample application zone, a developer supply zone, a developer absorption zone, and an influenza B virus detection zone, in which an influenza virus B antibody is immobilized on a matrix, moreover, the zones are defined on the matrix, and at least one of the following - labeled antibody to influenza B virus and antibody to influenza B virus immobilized in the detection zone - is a monoclonal antibody according to claim 1 or 2. 4. Устройство для иммунологического анализа по п.3, отличающееся тем, что дополнительно содержит меченое антитело к вирусу А гриппа в зоне меченого реагента, и зону детектирования вируса А гриппа, в которой иммобилизовано антитело к вирусу А гриппа, причем зона детектирования вируса А гриппа расположена вблизи зоны детектирования вируса В гриппа, в которой иммобилизовано антитело к вирусу В гриппа.4. The device for immunological analysis according to claim 3, characterized in that it further comprises a labeled antibody to influenza A virus in the zone of the labeled reagent, and a detection zone of influenza A virus in which the antibody to influenza A virus is immobilized, wherein the detection zone of influenza A virus located near the detection zone of influenza B virus, in which an antibody to influenza B virus is immobilized. 5. Устройство для иммунологического анализа по п.3 или 4, отличающееся тем, что меткой является фермент, и устройство содержит субстрат для этого фермента в составе проявителя и/или вблизи зоны подачи проявителя.5. The device for immunological analysis according to claim 3 or 4, characterized in that the label is an enzyme, and the device contains a substrate for this enzyme in the composition of the developer and / or near the developer supply zone.
RU2006103302/13A 2003-07-23 2004-07-23 Immunoassay device with using influenza b virus antibody RU2366663C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003-278528 2003-07-23
JP2003278528 2003-07-23

Publications (2)

Publication Number Publication Date
RU2006103302A true RU2006103302A (en) 2007-09-10
RU2366663C2 RU2366663C2 (en) 2009-09-10

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RU2006103302/13A RU2366663C2 (en) 2003-07-23 2004-07-23 Immunoassay device with using influenza b virus antibody

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JP (1) JPWO2005007698A1 (en)
KR (1) KR20060054333A (en)
CN (1) CN100441597C (en)
HK (1) HK1096975A1 (en)
RU (1) RU2366663C2 (en)
WO (1) WO2005007698A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2491338C2 (en) * 2011-06-30 2013-08-27 Федеральное государственное бюджетное учреждение "Научно-исследовательский Институт гриппа" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ гриппа" Минздравсоцразвития России) Using monoclonal antibodies for identifying yamagata or victorian influenza b viral evolution line, hybridoma 4h7 strain for preparing monoclonal antibodies used to identify influenza b viruses in yamagata branch, hybridoma b/4h1 strain for preparing monoclonal antibodies used to identify influenza b viruses in victorian branch

Families Citing this family (13)

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EP2309264A4 (en) * 2008-06-06 2011-11-23 Univ Toyama Nat Univ Corp Device for detection of influenza virus
US9903864B2 (en) 2009-04-09 2018-02-27 Arkray, Inc. Sample analysis tool, method for producing sample analysis tool, and method for inhibiting decrease in liquid permeability of development member
JP2010261912A (en) * 2009-05-11 2010-11-18 Bl:Kk Immunology-detection method of human influenza virus h3 subtype
JP5567932B2 (en) * 2010-08-03 2014-08-06 田中貴金属工業株式会社 Reagent composition for immunochromatography and measuring method using the same
TW201346040A (en) 2012-03-30 2013-11-16 Tanaka Precious Metal Ind Kit for identifying influenza a virus
JP6182027B2 (en) * 2013-09-10 2017-08-16 デンカ生研株式会社 Method for measuring influenza B virus
JP6262969B2 (en) 2013-09-10 2018-01-17 デンカ生研株式会社 Method for measuring influenza A virus
US20160377616A1 (en) * 2013-11-29 2016-12-29 Sekisui Medical Co., Ltd. Immunochromatographic detection method
EP3375875A4 (en) * 2015-11-09 2018-12-05 National University Corporation Kyoto Institute of Technology SEPARATING AGENT FOR HUMAN SERUM-DERIVED IgG POLYCLONAL ANTIBODIES, AND METHOD FOR SEPARATING HUMAN SERUM-DERIVED IgG POLYCLONAL ANTIBODIES USING SAME
JP7065338B2 (en) * 2017-09-12 2022-05-12 パナソニックＩｐマネジメント株式会社 Antibodies and complexes that bind to influenza virus nuclear proteins, detection devices and detection methods using them
CN114276441B (en) * 2020-09-27 2022-12-27 东莞市朋志生物科技有限公司 Anti-influenza B virus antibody, preparation method thereof and detection kit
CN114276440B (en) * 2020-09-27 2022-12-27 东莞市朋志生物科技有限公司 Antibody and detection kit for influenza B virus
CN117384279A (en) * 2022-07-05 2024-01-12 东莞市朋志生物科技有限公司 Anti-influenza B virus antibody, and reagent and kit for detecting influenza B virus

Family Cites Families (2)

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JP2518607B2 (en) * 1985-08-29 1996-07-24 雪印乳業株式会社 Monoclonal antibody against influenza A virus HA antigen and method for producing the same
JP3334558B2 (en) * 1997-04-23 2002-10-15 富士レビオ株式会社 Enzyme immunoassay and test strips

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2491338C2 (en) * 2011-06-30 2013-08-27 Федеральное государственное бюджетное учреждение "Научно-исследовательский Институт гриппа" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ гриппа" Минздравсоцразвития России) Using monoclonal antibodies for identifying yamagata or victorian influenza b viral evolution line, hybridoma 4h7 strain for preparing monoclonal antibodies used to identify influenza b viruses in yamagata branch, hybridoma b/4h1 strain for preparing monoclonal antibodies used to identify influenza b viruses in victorian branch

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WO2005007698A1 (en) 2005-01-27
CN100441597C (en) 2008-12-10
JPWO2005007698A1 (en) 2008-01-17
HK1096975A1 (en) 2007-06-15
CN1826355A (en) 2006-08-30
RU2366663C2 (en) 2009-09-10
KR20060054333A (en) 2006-05-22

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Effective date: 20140724