RU2004117904A - COMPREHENSIVE ANTI-HIV COMPOUND - Google Patents

COMPREHENSIVE ANTI-HIV COMPOUND Download PDF

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Publication number
RU2004117904A
RU2004117904A RU2004117904/15A RU2004117904A RU2004117904A RU 2004117904 A RU2004117904 A RU 2004117904A RU 2004117904/15 A RU2004117904/15 A RU 2004117904/15A RU 2004117904 A RU2004117904 A RU 2004117904A RU 2004117904 A RU2004117904 A RU 2004117904A
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RU
Russia
Prior art keywords
hiv
peptide fragment
hiv compound
comprehensive anti
ccr5
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RU2004117904/15A
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Russian (ru)
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RU2270690C1 (en
Inventor
Игорь Васильевич Тимофеев (RU)
Игорь Васильевич Тимофеев
Александр Владимирович Сербин (RU)
Александр Владимирович Сербин
Натали Георгиевна Перминова (RU)
Наталия Георгиевна Перминова
Денис Игоревич Тимофеев (RU)
Денис Игоревич Тимофеев
сунова Ольга Александровна Пл (RU)
Ольга Александровна Плясунова
Виталий Валентинович Неклюдов (RU)
Виталий Валентинович Неклюдов
Николай Николаевич Карпышев (RU)
Николай Николаевич Карпышев
Original Assignee
Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") (RU)
Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор")
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Application filed by Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") (RU), Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") filed Critical Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") (RU)
Priority to RU2004117904/15A priority Critical patent/RU2270690C1/en
Publication of RU2004117904A publication Critical patent/RU2004117904A/en
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Publication of RU2270690C1 publication Critical patent/RU2270690C1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (3)

Комплексное анти-ВИЧ соединение, включающее полианионную матрицу и химически с ней связанный псевдолиганд для gp120 ВИЧ-1/2, отличающееся тем, что псевдолиганд для gp120 ВИЧ-1/2 содержит пептидный фрагмент корецептора ВИЧ-1/2 CCR5 или CXCR4, а полианионная матрица и связанный с ней пептидный фрагмент корецептора ВИЧ-1/2 CCR5 или CXCR4 имеет следующую общую формулу:A complex anti-HIV compound comprising a polyanionic matrix and chemically bonded pseudo-ligand for gp120 HIV-1/2, characterized in that the pseudo-ligand for gp120 HIV-1/2 contains a peptide fragment of the HIV-1/2 co-receptor CCR5 or CXCR4, and the polyanionic the matrix and its associated peptide fragment of the HIV-1/2 CCR5 or CXCR4 coreceptor has the following general formula:
Figure 00000001
Figure 00000001
 2. Комплексное анти-ВИЧ соединение по п.1, отличающееся тем, что пептидный фрагмент корецептора ВИЧ-1/2 CCR5 имеет следующую формулу:2. The complex anti-HIV compound according to claim 1, characterized in that the peptide fragment of the HIV-1/2 CCR5 coreceptor has the following formula:
Figure 00000002
Figure 00000002
 3. Комплексное анти-ВИЧ соединение, по п.1, отличающееся тем, что пептидный фрагмент корецептора ВИЧ-1/2 CXCR4 имеет следующую формулу:3. The complex anti-HIV compound according to claim 1, characterized in that the peptide fragment of the HIV-1/2 CXCR4 coreceptor has the following formula:
Figure 00000003
Figure 00000003
RU2004117904/15A 2004-06-11 2004-06-11 Complex anti-hiv compound RU2270690C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2004117904/15A RU2270690C1 (en) 2004-06-11 2004-06-11 Complex anti-hiv compound

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Application Number Priority Date Filing Date Title
RU2004117904/15A RU2270690C1 (en) 2004-06-11 2004-06-11 Complex anti-hiv compound

Publications (2)

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RU2004117904A true RU2004117904A (en) 2006-01-10
RU2270690C1 RU2270690C1 (en) 2006-02-27

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2505210A1 (en) * 2011-03-18 2012-10-03 Institut Pasteur Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of aids

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Effective date: 20100805

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Effective date: 20150612