RU2003116131A - APPLICATION OF ENZYMES OBTAINED FROM INFUSORIES AS AN ASSOCIATED DIGESTIVE MEDICINES - Google Patents

APPLICATION OF ENZYMES OBTAINED FROM INFUSORIES AS AN ASSOCIATED DIGESTIVE MEDICINES

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Publication number
RU2003116131A
RU2003116131A RU2003116131/15A RU2003116131A RU2003116131A RU 2003116131 A RU2003116131 A RU 2003116131A RU 2003116131/15 A RU2003116131/15 A RU 2003116131/15A RU 2003116131 A RU2003116131 A RU 2003116131A RU 2003116131 A RU2003116131 A RU 2003116131A
Authority
RU
Russia
Prior art keywords
enzymes
drug
ciliates
drug according
infusories
Prior art date
Application number
RU2003116131/15A
Other languages
Russian (ru)
Other versions
RU2299074C2 (en
Inventor
Маркус ХАРТМАНН
Original Assignee
Цилиан Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Цилиан Аг filed Critical Цилиан Аг
Publication of RU2003116131A publication Critical patent/RU2003116131A/en
Application granted granted Critical
Publication of RU2299074C2 publication Critical patent/RU2299074C2/en

Links

Claims (7)

1. Лекарственное средство, содержащее ферменты из инфузорий, выбираемые из группы, состоящей из гидролаз, липаз, протеаз, амилаз, гликозидаз, фосфолипаз, фосфодиэстераз, фосфатаз.1. A drug containing enzymes from ciliates selected from the group consisting of hydrolases, lipases, proteases, amylases, glycosidases, phospholipases, phosphodiesterases, phosphatases. 2. Лекарственное средство по п.1, отличающееся тем, что ферменты обладают оптимальным значением рН от 4 до 6.2. The drug according to claim 1, characterized in that the enzymes have an optimal pH value from 4 to 6. 3. Лекарственное средство по любому из п.п.1 и/или 2, отличающееся тем, что ферменты происходят из инфузорий рода Tetrahymena, Colpidium, Paramecium.3. The drug according to any one of claims 1 and / or 2, characterized in that the enzymes come from ciliates of the genus Tetrahymena, Colpidium, Paramecium. 4. Лекарственное средство по любому из п.п.1-3, отличающееся тем, что оно содержит фармацевтические вспомогательные вещества и носители.4. The drug according to any one of claims 1 to 3, characterized in that it contains pharmaceutical excipients and carriers. 5. Лекарственное средство по любому из п.п.1-4, отличающееся тем, что оно находится в форме таблеток, микрогранул, масел, соков, гелей, суппозиториев, капсул, драже.5. The drug according to any one of claims 1 to 4, characterized in that it is in the form of tablets, microgranules, oils, juices, gels, suppositories, capsules, dragees. 6. Применение ферментов из инфузорий, выбираемых из группы, состоящей из гидролаз, липаз, протеаз, амилаз, гликозидаз, фосфолипаз, фосфодиэстераз и/или фосфатаз для приготовления лекарственного средства для лечения нарушения пищеварения.6. The use of enzymes from ciliates selected from the group consisting of hydrolases, lipases, proteases, amylases, glycosidases, phospholipases, phosphodiesterases and / or phosphatases for the preparation of a medicament for the treatment of digestive disorders. 7. Применение по п.6, в котором нарушения пищеварения вызваны медикаментозно обусловленной диспепсией, хроническим атропическим гастритом, хроническим панкреатитом, острым панкреатитом, оперативно обусловленным нарушением пищеварения или кистозным фиброзом.7. The use according to claim 6, in which digestive disorders are caused by drug-induced dyspepsia, chronic atropic gastritis, chronic pancreatitis, acute pancreatitis, operatively caused by an indigestion or cystic fibrosis.
RU2003116131/15A 2000-11-02 2001-11-02 Using enzymes prepared from infusoria as digestion-promoting medicinal agents RU2299074C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10054239.5 2000-11-02
DE10054239 2000-11-02

Publications (2)

Publication Number Publication Date
RU2003116131A true RU2003116131A (en) 2004-12-20
RU2299074C2 RU2299074C2 (en) 2007-05-20

Family

ID=7661849

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003116131/15A RU2299074C2 (en) 2000-11-02 2001-11-02 Using enzymes prepared from infusoria as digestion-promoting medicinal agents

Country Status (17)

Country Link
US (2) US20040033220A1 (en)
EP (1) EP1330262B1 (en)
JP (1) JP4139215B2 (en)
CN (1) CN1262308C (en)
AT (1) ATE295737T1 (en)
AU (2) AU2366602A (en)
CA (1) CA2427537A1 (en)
DE (1) DE50106273D1 (en)
DK (1) DK1330262T3 (en)
ES (1) ES2239686T3 (en)
HK (1) HK1057861A1 (en)
IL (2) IL155515A0 (en)
NO (1) NO20031979L (en)
PL (1) PL204599B1 (en)
PT (1) PT1330262E (en)
RU (1) RU2299074C2 (en)
WO (1) WO2002036156A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7459155B2 (en) * 2003-10-29 2008-12-02 Altus Pharmaceuticals Inc. Treating abdominal pain due to pancreatitis with seaprose
AU2005227090B2 (en) * 2004-03-22 2010-12-09 Abbott Laboratories Gmbh Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants
WO2005098427A2 (en) * 2004-04-05 2005-10-20 Arbab Saccharides Science & Technology Co. Ltd Method, composition and device for treating starch related diseases
WO2005099748A1 (en) * 2004-04-13 2005-10-27 Cilian Ag Recombinant lysosomal enzymes comprising a glycosylation pattern typical of ciliates for treatment
KR101555058B1 (en) * 2005-07-29 2015-09-22 애보트 래버러토리즈 게엠베하 Processes for the Manufacture of Sterilized Pancreatin Powder
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US8071089B2 (en) * 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
US10072256B2 (en) * 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110171294A1 (en) * 2008-09-30 2011-07-14 Dsm Ip Assets B.V. Enzyme composition and application thereof in the treatment of pancreatic insufficiency
GB201501081D0 (en) * 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
AU2022254851A1 (en) * 2021-04-09 2023-11-23 Cilian Ag Purification of proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454566B (en) * 1984-04-24 1988-05-16 Lars G I Hellgren PHARMACEUTICAL COMPOSITION CONTAINING AN ACTIVE AMOUNT OF WATER-SOLUBLE PROTEINASES EXTRACTED FROM A WATER-LIVING ANIMAL SELECTED BY THE EUPHAUSIACEAE OR GENERAL MALLOTUS
CA2110497C (en) * 1991-07-01 2005-04-19 Reinhard Braatz Use of bacterial lipases for producing drugs for maldigestion therapy
DE19524307A1 (en) * 1995-07-07 1997-01-09 Hoechst Ag Process for the mass cultivation of ciliates
DE19724845A1 (en) * 1996-08-28 1998-03-05 Solvay Pharm Gmbh Use of complex lipids as stabilizing additives for pharmaceutical preparations of digestive enzyme mixtures
US6846481B1 (en) * 1999-02-04 2005-01-25 University Of Georgia Research Foundation, Inc. Recombinant expression of heterologous nucleic acids in protozoa
US6539128B1 (en) * 1999-04-16 2003-03-25 Macronix International Co., Ltd. Method and apparatus for interpolation
US6543100B1 (en) * 2001-09-24 2003-04-08 Christopher J. Finley Test tube retention system

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