RU2002134002A - METHOD FOR DIAGNOSTIC OF ENDOGENIC INTOXICATION SYNDROME - Google Patents

METHOD FOR DIAGNOSTIC OF ENDOGENIC INTOXICATION SYNDROME

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Publication number
RU2002134002A
RU2002134002A RU2002134002/15A RU2002134002A RU2002134002A RU 2002134002 A RU2002134002 A RU 2002134002A RU 2002134002/15 A RU2002134002/15 A RU 2002134002/15A RU 2002134002 A RU2002134002 A RU 2002134002A RU 2002134002 A RU2002134002 A RU 2002134002A
Authority
RU
Russia
Prior art keywords
red blood
blood cells
control
concentration
intoxication syndrome
Prior art date
Application number
RU2002134002/15A
Other languages
Russian (ru)
Other versions
RU2234095C1 (en
Inventor
Вадим Михайлович Лазарев
Original Assignee
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Filing date
Publication date
Application filed by Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова filed Critical Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Priority to RU2002134002/15A priority Critical patent/RU2234095C1/en
Priority claimed from RU2002134002/15A external-priority patent/RU2234095C1/en
Publication of RU2002134002A publication Critical patent/RU2002134002A/en
Application granted granted Critical
Publication of RU2234095C1 publication Critical patent/RU2234095C1/en

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Claims (1)

Способ диагностики синдрома эндогенной интоксикации, включающий оценку проницаемости мембран эритроцитов, отличающийся тем, что определяют эритроциты, имеющие мембрану, блокированную циркулирующими иммунными комплексами, для чего оценивают проницаемость мембран эритроцитов в присутствии водного раствора NaCl в разведениях, производят подсчет количества негемолизированных эритроцитов в “камере Горяева” и в качестве контроля берут пробу с наименьшим количеством негемолизированных эритроцитов, проводят исследование при контрольной концентрации NaCI и концентрации эритроцитов в 10 раз превышающей концентрацию эритроцитов в контрольной пробе, определяют количество негемолизированных эритроцитов и при их количестве более чем в 10 раз превышающем контрольное диагностируют синдром эндогенной интоксикации.A method for diagnosing endogenous intoxication syndrome, including assessing the permeability of erythrocyte membranes, characterized in that erythrocytes having a membrane blocked by circulating immune complexes are determined, for which the permeability of erythrocyte membranes in the presence of an aqueous solution of NaCl in dilutions is estimated, and the number of non-hemolyzed erythrocytes in the cells is calculated. "And as a control take a sample with the least amount of non-hemolyzed red blood cells, conduct a study with a control the concentration of NaCI and the concentration of red blood cells 10 times higher than the concentration of red blood cells in the control sample, determine the number of non-hemolyzed red blood cells and when their number is more than 10 times higher than the control, they diagnose endogenous intoxication syndrome.
RU2002134002/15A 2002-12-18 2002-12-18 Method for diagnosis of endogenous intoxication syndrome RU2234095C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2002134002/15A RU2234095C1 (en) 2002-12-18 2002-12-18 Method for diagnosis of endogenous intoxication syndrome

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2002134002/15A RU2234095C1 (en) 2002-12-18 2002-12-18 Method for diagnosis of endogenous intoxication syndrome

Publications (2)

Publication Number Publication Date
RU2002134002A true RU2002134002A (en) 2004-07-10
RU2234095C1 RU2234095C1 (en) 2004-08-10

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Family Applications (1)

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RU2002134002/15A RU2234095C1 (en) 2002-12-18 2002-12-18 Method for diagnosis of endogenous intoxication syndrome

Country Status (1)

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RU (1) RU2234095C1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA012207B1 (en) * 2006-11-10 2009-08-28 Ргкп "Научно-Исследовательский Институт Кардиологии И Внутренних Болезней" Министерства Здравоохранения Республики Казахстан Method of early detection of organism endogenous intoxication
RU2475749C1 (en) * 2011-10-13 2013-02-20 Федеральное бюджетное учреждение науки "Уфимский научно-исследовательский институт медицины труда и экологии человека" Method of diagnosing syndrome of endogenic intoxication in workers of petrochemical and chemical enterprises
RU2494403C2 (en) * 2012-01-16 2013-09-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Казанский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации Method for assessing drug effect on permeability of cell membranes by sodium
RU2522877C2 (en) * 2012-03-20 2014-07-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт общей реаниматологии имени В.А. Неговского" Российской академии медицинских наук Method for laboratory assessment of effectiveness in treatment of intoxication in emergency patients

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