RU2002122429A - Способ получения 1-бета-D-рибофуранозил-1,2,4-триазол-3-карбоксамида (рибавирина) - Google Patents
Способ получения 1-бета-D-рибофуранозил-1,2,4-триазол-3-карбоксамида (рибавирина)Info
- Publication number
- RU2002122429A RU2002122429A RU2002122429/13A RU2002122429A RU2002122429A RU 2002122429 A RU2002122429 A RU 2002122429A RU 2002122429/13 A RU2002122429/13 A RU 2002122429/13A RU 2002122429 A RU2002122429 A RU 2002122429A RU 2002122429 A RU2002122429 A RU 2002122429A
- Authority
- RU
- Russia
- Prior art keywords
- carboxamide
- triazole
- ribavirin
- ribofuranosyl
- beta
- Prior art date
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Claims (1)
- Способ получения рибавирина путем трансгликозилирования 1,2,4-триазол-3-карбоксамида в присутствии ферментного препарата с последующим выделением целевого продукта, отличающийся тем, что в качестве ферментного препарата используют рекомбинантную пуриннуклеозид-фосфорилазу, иммобилизованную на водонерастворимом полимерном сорбенте.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2002122429/13A RU2230118C2 (ru) | 2002-08-21 | 2002-08-21 | СПОСОБ ПОЛУЧЕНИЯ 1-β-D-РИБОФУРАНОЗИЛ-1,2,4-ТРИАЗОЛ-3-КАРБОКСИАМИДА (РИБАВИРИНА) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2002122429/13A RU2230118C2 (ru) | 2002-08-21 | 2002-08-21 | СПОСОБ ПОЛУЧЕНИЯ 1-β-D-РИБОФУРАНОЗИЛ-1,2,4-ТРИАЗОЛ-3-КАРБОКСИАМИДА (РИБАВИРИНА) |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2002122429A true RU2002122429A (ru) | 2004-03-10 |
RU2230118C2 RU2230118C2 (ru) | 2004-06-10 |
Family
ID=32845990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2002122429/13A RU2230118C2 (ru) | 2002-08-21 | 2002-08-21 | СПОСОБ ПОЛУЧЕНИЯ 1-β-D-РИБОФУРАНОЗИЛ-1,2,4-ТРИАЗОЛ-3-КАРБОКСИАМИДА (РИБАВИРИНА) |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2230118C2 (ru) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101974585A (zh) * | 2010-11-02 | 2011-02-16 | 天津科技大学 | 一种微生物产酶发酵酶法生产抗病毒药物利巴韦林的工艺 |
RU2480218C1 (ru) * | 2011-12-06 | 2013-04-27 | Российская Федерация, От Имени Которой Выступает Министерство Промышленности И Торговли Российской Федерации | СПОСОБ ПОЛУЧЕНИЯ 1-β-D-РИБОФУРАНОЗИЛ-1,2,4-ТРИАЗОЛ-3-КАРБОКСАМИДА |
-
2002
- 2002-08-21 RU RU2002122429/13A patent/RU2230118C2/ru not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2230118C2 (ru) | 2004-06-10 |
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Legal Events
Date | Code | Title | Description |
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PD4A | Correction of name of patent owner | ||
QB4A | Licence on use of patent |
Free format text: LICENCE Effective date: 20131024 |
|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20170822 |