RU2001132140A - Recombinant platelet collagen receptor glycoprotein VI and its use in pharmaceuticals - Google Patents
Recombinant platelet collagen receptor glycoprotein VI and its use in pharmaceuticalsInfo
- Publication number
- RU2001132140A RU2001132140A RU2001132140/13A RU2001132140A RU2001132140A RU 2001132140 A RU2001132140 A RU 2001132140A RU 2001132140/13 A RU2001132140/13 A RU 2001132140/13A RU 2001132140 A RU2001132140 A RU 2001132140A RU 2001132140 A RU2001132140 A RU 2001132140A
- Authority
- RU
- Russia
- Prior art keywords
- sequence shown
- glycoprotein
- platelet
- recombinant
- gpvi
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims 3
- 102100016494 CD36 Human genes 0.000 title 1
- 229920003013 deoxyribonucleic acid Polymers 0.000 claims 4
- 210000001772 Blood Platelets Anatomy 0.000 claims 3
- 208000008787 Cardiovascular Disease Diseases 0.000 claims 3
- 102100018427 GP6 Human genes 0.000 claims 3
- 101700079100 GP6 Proteins 0.000 claims 3
- 102000003886 Glycoproteins Human genes 0.000 claims 3
- 108090000288 Glycoproteins Proteins 0.000 claims 3
- 208000007536 Thrombosis Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 206010010904 Convulsion Diseases 0.000 claims 1
- 206010039911 Seizure Diseases 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 229960005188 collagen Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99109094.5 | 1999-05-07 | ||
EP99109094 | 1999-05-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2001132140A true RU2001132140A (en) | 2003-08-10 |
RU2287580C2 RU2287580C2 (en) | 2006-11-20 |
Family
ID=8238132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2001132140/13A RU2287580C2 (en) | 1999-05-07 | 2000-04-25 | Glycoprotein vi as collagen recombinant receptor on platelets and its using in pharmaceutics |
Country Status (26)
Country | Link |
---|---|
US (5) | US7928066B1 (en) |
EP (3) | EP1942186B1 (en) |
JP (2) | JP5480457B2 (en) |
KR (1) | KR100703592B1 (en) |
CN (1) | CN1253569C (en) |
AR (1) | AR023848A1 (en) |
AT (1) | ATE393223T1 (en) |
AU (1) | AU775952B2 (en) |
BR (1) | BRPI0010325B1 (en) |
CA (1) | CA2372515C (en) |
CY (2) | CY1108190T1 (en) |
CZ (1) | CZ302693B6 (en) |
DE (1) | DE60038675T2 (en) |
DK (2) | DK1177289T3 (en) |
ES (2) | ES2534652T3 (en) |
HK (1) | HK1045714B (en) |
HU (1) | HUP0201049A2 (en) |
MX (1) | MXPA01011274A (en) |
NO (1) | NO333408B1 (en) |
PL (1) | PL204449B1 (en) |
PT (2) | PT2341141E (en) |
RU (1) | RU2287580C2 (en) |
SI (1) | SI1177289T1 (en) |
SK (1) | SK15762001A3 (en) |
WO (1) | WO2000068377A1 (en) |
ZA (1) | ZA200110071B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK15762001A3 (en) | 1999-05-07 | 2002-04-04 | Merck Patent Gmbh | Recombinant platelet collagen receptor glycoprotein vi and its pharmaceutical use |
US7291714B1 (en) | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
US6245527B1 (en) | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
AU7097400A (en) * | 1999-09-01 | 2001-03-26 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
EP1224942A1 (en) * | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
EP1406929A2 (en) * | 2001-07-18 | 2004-04-14 | MERCK PATENT GmbH | Glycoprotein vi fusion proteins |
US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
EP1369128A1 (en) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
US20070071744A1 (en) | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
DE102004017295A1 (en) * | 2004-04-05 | 2005-11-03 | Zlb Behring Gmbh | Compounds which cause or prevent the removal of receptors from cell membranes, and methods for their detection |
CN1964990B (en) | 2004-04-29 | 2012-12-12 | 大冢制药株式会社 | Antibodies specific for glycoprotein VI and methods of producing these antibodies |
US7645592B2 (en) | 2004-04-29 | 2010-01-12 | Otsuka Pharmaceutical Co., Ltd. | Glycoprotein VI antibodies and methods of use thereof |
WO2006117910A1 (en) | 2005-04-28 | 2006-11-09 | Mochida Pharmaceutical Co., Ltd. | Monoclonal antibody against platelet membrane glycoprotein vi |
RU2010121878A (en) * | 2007-10-31 | 2011-12-10 | Оцука Фармасьютикал Ко., Лтд. (Jp) | Glycoprotein VI Inhibitor (GPVI) |
EP2694709B1 (en) | 2011-04-08 | 2016-09-14 | Prognosys Biosciences, Inc. | Peptide constructs and assay systems |
EP3184544A1 (en) * | 2015-12-23 | 2017-06-28 | Julius-Maximilians-Universität Würzburg | Glycoprotein v inhibitors for use as coagulants |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT662088E (en) | 1993-07-01 | 2002-06-28 | Merck Patent Gmbh | INHIBITOR OF COLLAGENIC STIMULATED PLATELETS AGGREGATION |
AU701576B2 (en) * | 1993-10-22 | 1999-02-04 | Trigen Limited | Platelet-derived growth factor analogues |
AU5927398A (en) * | 1997-01-21 | 1998-08-07 | Human Genome Sciences, Inc. | Fc receptors and polypeptides |
CA2250291A1 (en) * | 1997-01-29 | 1998-07-30 | Toray Industries Inc. | Chimeric proteins, their heterodimer complexes, and platelet substitutes |
SK15762001A3 (en) | 1999-05-07 | 2002-04-04 | Merck Patent Gmbh | Recombinant platelet collagen receptor glycoprotein vi and its pharmaceutical use |
US7291714B1 (en) * | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
US6245527B1 (en) * | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
AU7097400A (en) * | 1999-09-01 | 2001-03-26 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
EP1406929A2 (en) | 2001-07-18 | 2004-04-14 | MERCK PATENT GmbH | Glycoprotein vi fusion proteins |
EP1538165A1 (en) | 2003-12-03 | 2005-06-08 | Procorde GmbH | Inhibitors of glycoprotein VI based on monoclonal antibody hgp 5c4 |
-
2000
- 2000-04-25 SK SK1576-2001A patent/SK15762001A3/en unknown
- 2000-04-25 DK DK00927035T patent/DK1177289T3/en active
- 2000-04-25 KR KR1020017014164A patent/KR100703592B1/en not_active IP Right Cessation
- 2000-04-25 DK DK11001216T patent/DK2341141T3/en active
- 2000-04-25 US US09/959,802 patent/US7928066B1/en not_active Expired - Fee Related
- 2000-04-25 ES ES11001216.8T patent/ES2534652T3/en not_active Expired - Lifetime
- 2000-04-25 HU HU0201049A patent/HUP0201049A2/en unknown
- 2000-04-25 EP EP08004264.1A patent/EP1942186B1/en not_active Expired - Lifetime
- 2000-04-25 CA CA2372515A patent/CA2372515C/en not_active Expired - Fee Related
- 2000-04-25 CZ CZ20013989A patent/CZ302693B6/en not_active IP Right Cessation
- 2000-04-25 PL PL351437A patent/PL204449B1/en unknown
- 2000-04-25 SI SI200030996T patent/SI1177289T1/en unknown
- 2000-04-25 JP JP2000616343A patent/JP5480457B2/en not_active Expired - Fee Related
- 2000-04-25 PT PT110012168T patent/PT2341141E/en unknown
- 2000-04-25 EP EP11001216.8A patent/EP2341141B1/en not_active Expired - Lifetime
- 2000-04-25 PT PT00927035T patent/PT1177289E/en unknown
- 2000-04-25 CN CNB008072922A patent/CN1253569C/en not_active Expired - Fee Related
- 2000-04-25 MX MXPA01011274A patent/MXPA01011274A/en active IP Right Grant
- 2000-04-25 DE DE60038675T patent/DE60038675T2/en not_active Expired - Lifetime
- 2000-04-25 BR BRPI0010325A patent/BRPI0010325B1/en not_active IP Right Cessation
- 2000-04-25 ES ES00927035T patent/ES2304347T3/en not_active Expired - Lifetime
- 2000-04-25 RU RU2001132140/13A patent/RU2287580C2/en not_active IP Right Cessation
- 2000-04-25 AU AU45555/00A patent/AU775952B2/en not_active Ceased
- 2000-04-25 EP EP00927035A patent/EP1177289B1/en not_active Expired - Lifetime
- 2000-04-25 WO PCT/EP2000/003683 patent/WO2000068377A1/en active IP Right Grant
- 2000-04-25 AT AT00927035T patent/ATE393223T1/en active
- 2000-05-04 AR ARP000102136A patent/AR023848A1/en unknown
-
2001
- 2001-11-06 NO NO20015420A patent/NO333408B1/en not_active IP Right Cessation
- 2001-12-06 ZA ZA200110071A patent/ZA200110071B/en unknown
-
2002
- 2002-09-26 HK HK02107061.7A patent/HK1045714B/en not_active IP Right Cessation
-
2007
- 2007-03-21 US US11/689,392 patent/US20070172480A1/en not_active Abandoned
- 2007-03-21 US US11/689,385 patent/US8198030B2/en not_active Expired - Lifetime
-
2008
- 2008-07-11 CY CY20081100731T patent/CY1108190T1/en unknown
-
2010
- 2010-12-20 JP JP2010283409A patent/JP5554696B2/en not_active Expired - Fee Related
-
2011
- 2011-03-11 US US13/046,210 patent/US8278430B2/en not_active Expired - Lifetime
-
2015
- 2015-04-09 CY CY20151100344T patent/CY1116336T1/en unknown
-
2016
- 2016-03-08 US US15/064,157 patent/US20160207976A1/en not_active Abandoned
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2001132140A (en) | Recombinant platelet collagen receptor glycoprotein VI and its use in pharmaceuticals | |
MX172600B (en) | , "PROCEDURE FOR THE PRODUCTION OF A BIOLOGICALLY ACTIVE PROTEIN | |
DK0910647T3 (en) | Human DNase in hyperactive variants | |
KR20010079669A (en) | Regulation of Substrate Activity | |
EA200300381A1 (en) | NUCLEIC ACIDS AND POLYPEPTIDES OF THE NEW RECEPTOR | |
DE69129248D1 (en) | Peptides with endothelin antagonistic activity, their preparation and pharmaceutical compositions | |
DE60121301D1 (en) | Flibanserin for the treatment of extrapyramidal movement disorders | |
ES2163444T3 (en) | COMPOSITIONS AND METHODS FOR THE ORAL ADMINISTRATION OF PHARMACOS. | |
RU2000124084A (en) | Chimeric antibody that binds to human CD40 (variants), nucleic acid molecule (variants), expression vector (variants), humanized antibody (variants), pharmaceutical composition for treating a T-cell mediated disease (variants), method for treating a patient for a disease mediated by T cells (options) | |
NO963568D0 (en) | Pharmaceutical composition for the treatment of blood coagulation disorders, methods for the preparation thereof and its use | |
KR910700260A (en) | Neutrophil-activated peptide-2 | |
RU98120519A (en) | AUTOANTIGEN AND STRUCTURAL-RELATED PROTEINS FOR USE IN IMMUNOTHERAPY OF AUTOIMMUNE DISEASES | |
DE69531004D1 (en) | p277 PEPTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF FOR THE TREATMENT AND DIAGNOSIS OF DIABETES | |
PT1079849E (en) | USE OF HMG PROTEINS FOR THE PREPARATION OF MEDICINES WITH CYTOTOXIC ACTIVITY | |
WO2004074486A3 (en) | Fusion proteins of interferon alpha muteins with improved properties | |
EA200600782A1 (en) | THERAPEUTIC APPLICATIONS OF HEMOKIN VARIANTS | |
HUP0500637A2 (en) | Polymer conjugates of neublastin and methods of using same | |
EA200401369A1 (en) | SLOWLY RELAXING MEDICINAL COMPOSITIONS OF GUIPHENESINE | |
WO2004067027A3 (en) | Osteogenic composition | |
DK1643999T3 (en) | Pyridoxamine for use in the treatment of diabetic nephropathy in type 2 diabetes | |
EE200100662A (en) | Anticoagulant compound, process for its preparation, pharmaceutical preparation containing it and therapeutic use thereof | |
HUP0102975A2 (en) | Chemotaxis-inhibiting protein of staphylococcus (chips) and its use | |
RU2005131578A (en) | APLIDINE FOR TREATMENT OF MULTIPLE MYELOMA | |
CA2455621A1 (en) | Use of (r/s)-(-/+) or (s)-(+)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chromane for the treatment of extrapyramidal movement disorders | |
BG103905A (en) | New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine |