RU2001104389A - MEANS FOR STIMULATION OF CELL PROLIFERATION, COMPOSITION FOR STIMULATION OF CELL PROLIFERATION AND METHOD OF TREATMENT OF THE RAS, BURNS AND ULCER OF VARIOUS ETIOLOGY - Google Patents
MEANS FOR STIMULATION OF CELL PROLIFERATION, COMPOSITION FOR STIMULATION OF CELL PROLIFERATION AND METHOD OF TREATMENT OF THE RAS, BURNS AND ULCER OF VARIOUS ETIOLOGYInfo
- Publication number
- RU2001104389A RU2001104389A RU2001104389/14A RU2001104389A RU2001104389A RU 2001104389 A RU2001104389 A RU 2001104389A RU 2001104389/14 A RU2001104389/14 A RU 2001104389/14A RU 2001104389 A RU2001104389 A RU 2001104389A RU 2001104389 A RU2001104389 A RU 2001104389A
- Authority
- RU
- Russia
- Prior art keywords
- composition
- extract
- cell proliferation
- sterile
- burns
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 20
- 206010068760 Ulcers Diseases 0.000 title claims 11
- 231100000397 ulcer Toxicity 0.000 title claims 11
- 230000035409 positive regulation of cell proliferation Effects 0.000 title 2
- 210000004556 Brain Anatomy 0.000 claims 17
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 12
- 239000011780 sodium chloride Substances 0.000 claims 10
- 200000000019 wound Diseases 0.000 claims 10
- 230000004663 cell proliferation Effects 0.000 claims 9
- 230000004936 stimulating Effects 0.000 claims 9
- 239000000243 solution Substances 0.000 claims 6
- ZFGMDIBRIDKWMY-PASTXAENSA-N Heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 claims 4
- 229960002897 Heparin Drugs 0.000 claims 4
- 229920000669 heparin Polymers 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 230000000844 anti-bacterial Effects 0.000 claims 3
- 230000000843 anti-fungal Effects 0.000 claims 3
- 239000003589 local anesthetic agent Substances 0.000 claims 3
- 210000003754 Fetus Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drugs Drugs 0.000 claims 2
- 239000003357 wound healing promoting agent Substances 0.000 claims 2
- APKFDSVGJQXUKY-INPOYWNPSA-N BRL-49594 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 claims 1
- GPRBEKHLDVQUJE-VINNURBNSA-N Cefotaxime Chemical compound N([C@@H]1C(N2C(=C(COC(C)=O)CS[C@@H]21)C(O)=O)=O)C(=O)/C(=N/OC)C1=CSC(N)=N1 GPRBEKHLDVQUJE-VINNURBNSA-N 0.000 claims 1
- 229960004261 Cefotaxime Drugs 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Xylocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- 229960003942 amphotericin B Drugs 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000001605 fetal Effects 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
Claims (1)
Стерильный экстракт головного мозга человека на стадии его внутриутробного развития (по белку) - 0,1 - 100
Стерильный изотонический солевой раствор - Остальное
4. Состав для стимуляции пролиферации клеток по п. 3, отличающийся тем, что в качестве стерильного экстракта головного мозга человека на стадии его внутриутробного развития состав содержит экстракт головного мозга плода человека 16-24 недель.3. Composition for stimulating cell proliferation, containing an aqueous solution of brain extract, characterized in that as a brain extract, the composition contains a sterile extract of the human brain at the stage of its prenatal development in sterile isotonic saline solution in the following ratio of components, mg / ml:
Sterile extract of the human brain at the stage of its intrauterine development (protein) - 0.1 - 100
Sterile isotonic saline - the Rest
4. Composition for stimulating cell proliferation under item 3, characterized in that as a sterile extract of the human brain at the stage of its intrauterine development, the composition contains the extract of the brain of the human fetus 16-24 weeks.
Стерильный экстракт головного мозга человека на стадии его внутриутробного развития (по белку) - 0,1 - 100
Гепарин - 0,06 -15
Стерильный изотонический солевой раствор - Остальное
7. Состав для стимуляции пролиферации клеток по п. 3 или 6, отличающийся тем, что дополнительно содержит препарат, обладающий антибактериальной активностью, в количестве 0,05 - 200,0 мг/мл.6. Composition for stimulating cell proliferation under item 3, characterized in that it additionally contains heparin in the following ratio of components, mg / ml:
Sterile extract of the human brain at the stage of its intrauterine development (protein) - 0.1 - 100
Heparin - 0.06 -15
Sterile isotonic saline - the Rest
7. The composition for stimulating cell proliferation according to claim 3 or 6, characterized in that it additionally contains a drug with antibacterial activity in an amount of 0.05-200.0 mg / ml.
Стерильный экстракт головного мозга человека на стадии его внутриутробного развития (по белку) - 0,5 - 20,0
Стерильный изотонический солевой раствор - Остальное
11. Способ лечения ран, ожогов и язв различной этиологии по п. 10, отличающийся тем, что в качестве стерильного экстракта головного мозга человека на стадии его внутриутробного развития упомянутый состав содержит экстракт головного мозга плода человека 16-24 недель.10. A method of treating wounds, burns and ulcers of various etiologies, including local use of a wound-healing agent, characterized in that. that a composition containing sterile extract of a human brain at the stage of its prenatal development in sterile isotonic saline solution is used as a wound healing agent in the following ratio of components, mg / ml:
Sterile extract of the human brain at the stage of its intrauterine development (protein) - 0.5 - 20.0
Sterile isotonic saline - the Rest
11. A method of treating wounds, burns and ulcers of various etiologies in accordance with claim 10, characterized in that, as a sterile extract of the human brain at the stage of its intrauterine development, said composition contains an extract of the brain of the human fetus 16-24 weeks.
Стерильный экстракт головного мозга человека на стадии его внутриутробного развития (по белку) - 0,5 - 20,0
Гепарин - 0,6 - 12
Стерильный изотонический солевой раствор - Остальное
14. Способ лечения ран, ожогов и язв различной этиологии по п. 10 или 13, отличающийся тем, что упомянутый состав дополнительно содержит препарат, обладающий антибактериальной активностью, в количестве 0,05 - 10,0 мг/мл.13. A method of treating wounds, burns and ulcers of various etiologies under item 10, characterized in that said composition further comprises heparin in the following ratio of components, mg / ml:
Sterile extract of the human brain at the stage of its intrauterine development (protein) - 0.5 - 20.0
Heparin - 0.6 - 12
Sterile isotonic saline - the Rest
14. A method of treating wounds, burns and ulcers of various etiologies under item 10 or 13, characterized in that said composition additionally contains a preparation having antibacterial activity in an amount of 0.05-10.0 mg / ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2001104389/14A RU2214256C2 (en) | 2001-02-09 | 2001-02-09 | Agent for stimulation of cells proliferation, composite for stimulation of cells proliferation and method for treatment of wounds, burns and ulcers of different etiology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2001104389/14A RU2214256C2 (en) | 2001-02-09 | 2001-02-09 | Agent for stimulation of cells proliferation, composite for stimulation of cells proliferation and method for treatment of wounds, burns and ulcers of different etiology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2001104389A true RU2001104389A (en) | 2002-12-20 |
| RU2214256C2 RU2214256C2 (en) | 2003-10-20 |
Family
ID=31988073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2001104389/14A RU2214256C2 (en) | 2001-02-09 | 2001-02-09 | Agent for stimulation of cells proliferation, composite for stimulation of cells proliferation and method for treatment of wounds, burns and ulcers of different etiology |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2214256C2 (en) |
-
2001
- 2001-02-09 RU RU2001104389/14A patent/RU2214256C2/en not_active IP Right Cessation
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