RU2001102045A - LOCAL ACTION PLASTER WITH NON-STEROID ANTIRERUMATIC MEDICINES CONTAINING AN ACID GROUP - Google Patents

LOCAL ACTION PLASTER WITH NON-STEROID ANTIRERUMATIC MEDICINES CONTAINING AN ACID GROUP

Info

Publication number
RU2001102045A
RU2001102045A RU2001102045/14A RU2001102045A RU2001102045A RU 2001102045 A RU2001102045 A RU 2001102045A RU 2001102045/14 A RU2001102045/14 A RU 2001102045/14A RU 2001102045 A RU2001102045 A RU 2001102045A RU 2001102045 A RU2001102045 A RU 2001102045A
Authority
RU
Russia
Prior art keywords
patch according
active substance
local action
matrix
woven
Prior art date
Application number
RU2001102045/14A
Other languages
Russian (ru)
Other versions
RU2212232C2 (en
Inventor
Вальтер Мюллер
Original Assignee
Лтс Ломанн Терапи-Зюстеме Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19830649A external-priority patent/DE19830649C2/en
Application filed by Лтс Ломанн Терапи-Зюстеме Аг filed Critical Лтс Ломанн Терапи-Зюстеме Аг
Publication of RU2001102045A publication Critical patent/RU2001102045A/en
Application granted granted Critical
Publication of RU2212232C2 publication Critical patent/RU2212232C2/en

Links

Claims (11)

1. Обладающий местным действием пластырь, в качестве действующего вещества содержащий нестероидные антиревматические средства со свободной карбоксильной группой и состоящий из инертной по отношению к действующему веществу подложки, выполненной из материала, обладающего эластичностью, по меньшей мере, в одном направлении, содержащего действующее вещество самоклеящегося слоя матрицы на основе адгезивного полиакрилата, сшитого с ионами поливалентного металла и имеющего свободные карбоксильные группы, при этом упомянутая матрица содержит жирную кислоту, и защитной пленки, которую удаляют до использования, отличающийся тем, что упомянутая содержащая действующее вещество матрица состоит из одного слоя и не содержит свободные гидроксильные группы, а также тем, что упомянутая подложка выполнена из эластичного тканого или трикотажного материала на основе полиэфира или нетканого, тканого или трикотажного материала на основе полиэтилентерефталата или эластичного пенопласта с закрытыми ячейками.1. Having a local action patch, containing as an active substance non-steroidal anti-rheumatic drugs with a free carboxyl group and consisting of a substrate inert with respect to the active substance, made of a material having elasticity in at least one direction, containing the active substance of a self-adhesive layer matrices based on adhesive polyacrylate crosslinked with polyvalent metal ions and having free carboxyl groups, wherein said matrix contains lives fatty acid, and a protective film that is removed before use, characterized in that said active substance-containing matrix consists of one layer and does not contain free hydroxyl groups, and also that said substrate is made of an elastic woven or knitted material based on polyester or non-woven, woven or knitted material based on polyethylene terephthalate or closed-cell elastic foam. 2. Обладающий местным действием пластырь по п. 1, отличающийся тем, что нестероидное антревматическое средство представляет собой производное профена. 2. Having a local action patch according to claim 1, characterized in that the non-steroidal antirheumatic agent is a derivative of profen. 3. Обладающий местным действием пластырь по п. 2, отличающийся тем, что действующее вещество представляет собой кетопрофен, ибупрофен, флурпрофен или напроксен. 3. A topical patch according to claim 2, characterized in that the active substance is ketoprofen, ibuprofen, flurprofen or naproxen. 4. Обладающий местным действием пластырь по п. 3, отличающийся тем, что действующее вещество представляет собой кетопрофен или флурпрофен и содержится в матрице пластыря в концентрации 5 - 15 мас. %. 4. Having a local action patch according to claim 3, characterized in that the active substance is ketoprofen or flurprofen and is contained in the patch matrix in a concentration of 5-15 wt. % 5. Обладающий местным действием пластырь по п. 4, отличающийся тем, что действующее вещество представляет собой кетопрофен и присутствует в растворенном в матрице виде в концентрации 6-10 мас. %. 5. Having a local action patch according to claim 4, characterized in that the active substance is ketoprofen and is present in a form dissolved in the matrix at a concentration of 6-10 wt. % 6. Обладающий местным действием пластырь по п. 1, отличающийся тем, что жирная кислота представляет собой олеиновую, линолевую или линоленовую кислоты. 6. A topical patch according to claim 1, characterized in that the fatty acid is oleic, linoleic or linolenic acid. 7. Обладающий местным действием пластырь по п. 6, отличающийся тем, что жирная кислота представляет собой олеиновую кислоту, присутствующую в матрице пластыря в концентрации 5 - 20 мас. %. 7. A topical patch according to claim 6, characterized in that the fatty acid is oleic acid present in the matrix of the patch at a concentration of 5 to 20 wt. % 8. Обладающий местным действием пластырь по п. 1, отличающийся тем, что адгезивное вещество на основе полиакрилата получено с использованием, по меньшей мере, 2-этилегексилакрилата и акриловой кислоты. 8. A topical patch according to claim 1, characterized in that the adhesive based on polyacrylate is prepared using at least 2-ethylhexyl acrylate and acrylic acid. 9. Обладающий местным действием пластырь по п. 1, отличающийся тем, что адгезивное вещество па основе полиакрилата получено с использованием 2-этилегексилакрилата, винилацетата, акриловой кислоты, бутилакрилата. 9. A topical patch according to claim 1, characterized in that the adhesive substance based on polyacrylate is prepared using 2-ethylhexyl acrylate, vinyl acetate, acrylic acid, butyl acrylate. 10. Обладающий местным действием пластырь по п. 1, отличающийся тем, что подложка состоит из тканого материала на основе полиэтилентерефталата, обладающего эластичностью в двух направлениях. 10. Having a local action patch according to claim 1, characterized in that the substrate consists of a woven material based on polyethylene terephthalate having elasticity in two directions. 11. Обладающий местным действием пластырь по п. 1, отличающийся тем, что пенопласт с закрытыми ячейками состоит из полиэтилена, полипропилена, поливинилхлорида или сополимера этилена и винилацетата. 11. A topical patch according to claim 1, characterized in that the closed-cell foam consists of polyethylene, polypropylene, polyvinyl chloride or a copolymer of ethylene and vinyl acetate.
RU2001102045/14A 1998-07-09 1999-07-06 Local action plaster comprising non-steroid anti-rheumatic remedies containing acid group RU2212232C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19830649A DE19830649C2 (en) 1998-07-09 1998-07-09 Topical patch with nonsteroidal anti-inflammatory drugs with acid group
DE19830649.0 1998-07-09

Publications (2)

Publication Number Publication Date
RU2001102045A true RU2001102045A (en) 2003-01-20
RU2212232C2 RU2212232C2 (en) 2003-09-20

Family

ID=7873428

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2001102045/14A RU2212232C2 (en) 1998-07-09 1999-07-06 Local action plaster comprising non-steroid anti-rheumatic remedies containing acid group

Country Status (23)

Country Link
US (1) US6676962B1 (en)
EP (1) EP1094796B1 (en)
JP (1) JP2002520270A (en)
KR (1) KR100549847B1 (en)
CN (1) CN1222280C (en)
AR (1) AR019343A1 (en)
AT (1) ATE251900T1 (en)
AU (1) AU750861B2 (en)
BR (1) BR9911981B1 (en)
CA (1) CA2336732C (en)
CZ (1) CZ290992B6 (en)
DE (2) DE19830649C2 (en)
ES (1) ES2212584T3 (en)
HU (1) HU227839B1 (en)
IL (2) IL140744A0 (en)
MX (1) MXPA01000128A (en)
NZ (1) NZ509216A (en)
PL (1) PL192009B1 (en)
RU (1) RU2212232C2 (en)
TR (1) TR200100022T2 (en)
TW (1) TW577760B (en)
WO (1) WO2000002539A1 (en)
ZA (1) ZA200100172B (en)

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