RU2000109293A - Monoclonal antibody obtained using integrin-associated protein, its fragment Fab, Fab 'or F (ab') 2, hybridoma producing a monoclonal antibody (variant), antileukemic agent - Google Patents

Monoclonal antibody obtained using integrin-associated protein, its fragment Fab, Fab 'or F (ab') 2, hybridoma producing a monoclonal antibody (variant), antileukemic agent

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Publication number
RU2000109293A
RU2000109293A RU2000109293/13A RU2000109293A RU2000109293A RU 2000109293 A RU2000109293 A RU 2000109293A RU 2000109293/13 A RU2000109293/13 A RU 2000109293/13A RU 2000109293 A RU2000109293 A RU 2000109293A RU 2000109293 A RU2000109293 A RU 2000109293A
Authority
RU
Russia
Prior art keywords
monoclonal antibody
fab
associated protein
integrin
fragment
Prior art date
Application number
RU2000109293/13A
Other languages
Russian (ru)
Other versions
RU2212413C2 (en
Inventor
Наоси ФУКУСИМА
Синсуке УНО
Original Assignee
Чугаи Сейяку Кабусики Кайся
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чугаи Сейяку Кабусики Кайся filed Critical Чугаи Сейяку Кабусики Кайся
Publication of RU2000109293A publication Critical patent/RU2000109293A/en
Application granted granted Critical
Publication of RU2212413C2 publication Critical patent/RU2212413C2/en

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Claims (6)

1. Моноклональное антитело, индуцирующее апоптоз ядросодержащих клеток крови, содержащих интегринассоциированный белок (IAP).1. Monoclonal antibody inducing apoptosis of nucleated blood cells containing integrin-associated protein (IAP). 2. Фрагмент, пептид или низкомолекулярное соединение моноклонального антитела, индуцирующие апоптоз ядросодержащих клеток крови, содержащих интегринассоциированный белок (IAP).2. A fragment, peptide or low molecular weight monoclonal antibody inducing apoptosis of nucleated blood cells containing an integrally associated protein (IAP). 3. Гибридома, продуцирующая моноклональное антитело, охарактеризованное в п.1.3. A hybridoma producing the monoclonal antibody described in claim 1. 4. Противолейкозное средство, содержащее вещество, связывающееся с IAP и стимулирующее действие IAP, для индуцирования апоптоза ядросодержащих клеток крови.4. An anti-leukemia agent containing a substance that binds to IAP and stimulates the action of IAP to induce apoptosis of nucleated blood cells. 5. Противолейкозное средство по п.4, где указанным веществом является моноклональное антитело.5. The anti-leukemia agent according to claim 4, wherein said substance is a monoclonal antibody. 6. Противолейкозное средство по п.4, где указанным веществом является фрагмент, пептид или низкомолекулярное соединение моноклонального антитела.6. The anti-leukemia agent according to claim 4, where the specified substance is a fragment, peptide or low molecular weight compound of a monoclonal antibody.
RU2000109293/13A 1997-09-11 1998-09-11 Monoclonal antibody prepared using integrin-associated protein, its fragment fab, fab' or f(ab')2, hybridoma producing monoclonal antibody (variant), antileukemic agent RU2212413C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26485397 1997-09-11
JP9/264853 1997-09-11

Publications (2)

Publication Number Publication Date
RU2000109293A true RU2000109293A (en) 2003-06-20
RU2212413C2 RU2212413C2 (en) 2003-09-20

Family

ID=17409137

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000109293/13A RU2212413C2 (en) 1997-09-11 1998-09-11 Monoclonal antibody prepared using integrin-associated protein, its fragment fab, fab' or f(ab')2, hybridoma producing monoclonal antibody (variant), antileukemic agent

Country Status (14)

Country Link
US (1) US20030157100A1 (en)
EP (1) EP1035132B1 (en)
KR (2) KR20040106585A (en)
CN (1) CN1198845C (en)
AT (1) ATE395362T1 (en)
AU (1) AU740225B2 (en)
CA (1) CA2303072A1 (en)
DE (1) DE69839492D1 (en)
HU (1) HUP0003513A3 (en)
NO (1) NO20001238L (en)
PL (1) PL339265A1 (en)
RU (1) RU2212413C2 (en)
SK (1) SK3232000A3 (en)
WO (1) WO1999012973A1 (en)

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