RU2000104086A - METHOD FOR PRODUCING ORGANIC ASIDES - Google Patents

METHOD FOR PRODUCING ORGANIC ASIDES

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Publication number
RU2000104086A
RU2000104086A RU2000104086/04A RU2000104086A RU2000104086A RU 2000104086 A RU2000104086 A RU 2000104086A RU 2000104086/04 A RU2000104086/04 A RU 2000104086/04A RU 2000104086 A RU2000104086 A RU 2000104086A RU 2000104086 A RU2000104086 A RU 2000104086A
Authority
RU
Russia
Prior art keywords
organic compound
derivative
epoxy derivative
dianhydro
mannopyranose
Prior art date
Application number
RU2000104086/04A
Other languages
Russian (ru)
Other versions
RU2241714C2 (en
Inventor
Хенрикус Корнелис Йозефус КЛАССЕН
Original Assignee
Акцо Нобель Н.В.
Санофи-Синтелябо
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Акцо Нобель Н.В., Санофи-Синтелябо filed Critical Акцо Нобель Н.В.
Publication of RU2000104086A publication Critical patent/RU2000104086A/en
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Publication of RU2241714C2 publication Critical patent/RU2241714C2/en

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Claims (7)

1. Способ присоединения азидной функции к органическому соединению, в котором эпоксидное производное органического соединения и азидную соль щелочного металла вводят в реакцию в растворителе с получением азидного производного органического соединения, отличающийся тем, что до и/или во время реакции к реакционной смеси добавляют (1-6С)алкиловый эфир (2-4С)карбоновой кислоты, имеющий температуру кипения выше температуры реакции, в количестве близком к эквимолярному, по отношению к эпоксидному производному.1. A method of attaching an azide function to an organic compound in which an epoxy derivative of an organic compound and an alkali metal azide salt are reacted in a solvent to obtain an azide derivative of an organic compound, characterized in that they are added to the reaction mixture before and / or during the reaction (1 -6C) alkyl ester of (2-4C) carboxylic acid having a boiling point above the reaction temperature, in an amount close to equimolar with respect to the epoxy derivative. 2. Способ по п.1, отличающийся тем, что эпоксидное производное органического соединения, выбирают из оксида стирола, 2,3-эпоксибутана, оксида индена и эпоксидного производного углевода. 2. The method according to claim 1, characterized in that the epoxy derivative of the organic compound is selected from styrene oxide, 2,3-epoxybutane, indene oxide and an epoxy derivative of carbohydrate. 3. Способ по п.2, отличающийся тем, что эпоксидное производное органического соединения представляет производное углевода. 3. The method according to claim 2, characterized in that the epoxy derivative of the organic compound is a carbohydrate derivative. 4. Способ по п.3, отличающийся тем, что эпоксидным производным углевода является 1,6: 2,3-диангидро-4-О-фенилметил
Figure 00000001
D-маннопираноза или 1,6:2,3-диангидро-4-О-[2,3-бис-О-фенилметил-4,6-O-фенилметилиден
Figure 00000002
D-глюкопиранозил]
Figure 00000003
D-маннопираноза, или 1,6:2,3-диангидро-4-О-[2,3-бис-О-фенилметил-4,6-О-(1-метилэтилиден)
Figure 00000004
D-глюкопиранозил]
Figure 00000005
D-маннопираноза.4. The method according to claim 3, characterized in that the epoxy derivative of the carbohydrate is 1,6: 2,3-dianhydro-4-O-phenylmethyl
Figure 00000001
D-mannopyranose or 1.6: 2,3-dianhydro-4-O- [2,3-bis-O-phenylmethyl-4,6-O-phenylmethylidene
Figure 00000002
D-glucopyranosyl]
Figure 00000003
D-mannopyranose, or 1.6: 2,3-dianhydro-4-O- [2,3-bis-O-phenylmethyl-4,6-O- (1-methylethylidene)
Figure 00000004
D-glucopyranosyl]
Figure 00000005
D-mannopyranose. 5. Способ по любому из пп.1-4, отличающийся тем, что температура реакции составляет между 10 и 120oС.5. The method according to any one of claims 1 to 4, characterized in that the reaction temperature is between 10 and 120 o C. 6. Способ по любому из пп.1-5, отличающийся тем, что эфиром является бутилацетат. 6. The method according to any one of claims 1 to 5, characterized in that the ether is butyl acetate. 7. Способ по любому из пп.1-6, отличающийся тем, что к реакционной смеси добавляют воду в количестве самое большее равном объему растворителя. 7. The method according to any one of claims 1 to 6, characterized in that water is added to the reaction mixture in an amount at most equal to the volume of the solvent.
RU2000104086/04A 1999-02-19 2000-02-18 Method for preparing organic azides RU2241714C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99200484 1999-02-19
EP99200484.6 1999-02-19

Publications (2)

Publication Number Publication Date
RU2000104086A true RU2000104086A (en) 2001-10-27
RU2241714C2 RU2241714C2 (en) 2004-12-10

Family

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Country Status (23)

Country Link
US (1) US6232451B1 (en)
EP (1) EP1029867B1 (en)
JP (1) JP4347488B2 (en)
KR (1) KR100649058B1 (en)
CN (1) CN1156483C (en)
AR (1) AR022615A1 (en)
AT (1) ATE265463T1 (en)
AU (1) AU769027B2 (en)
BR (1) BRPI0000481B8 (en)
CA (1) CA2296902C (en)
CZ (1) CZ298569B6 (en)
DE (1) DE60010147T2 (en)
DK (1) DK1029867T3 (en)
ES (1) ES2216810T3 (en)
HU (1) HUP0000740A3 (en)
IL (1) IL134144A (en)
NO (1) NO314265B1 (en)
NZ (1) NZ502829A (en)
PL (1) PL198390B1 (en)
PT (1) PT1029867E (en)
RU (1) RU2241714C2 (en)
TR (1) TR200000441A3 (en)
ZA (1) ZA200000578B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8242344B2 (en) * 2002-06-26 2012-08-14 Fingersteps, Inc. Method and apparatus for composing and performing music
FR2935976B1 (en) * 2008-09-16 2010-12-17 Sanofi Aventis SHORT SYNTHESIS ROUTE OF 1,6: 2,3-DIANHYDRO-B-D-MANNOPYRANOSE.
FR2935975B1 (en) * 2008-09-16 2010-12-17 Sanofi Aventis PROCESS FOR PREPARING 1,6: 2,3-DIANHYDRO-B-D-MANNOPYRANOSE
CN103819357B (en) * 2014-01-28 2016-03-16 浙江大学 The preparation method of (-)-effective mould alcohol nitrine tetraacetate
WO2020006476A1 (en) * 2018-06-29 2020-01-02 Georgia State University Research Foundation, Inc. Environmentally-friendly hydroazidation of olefins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3893997A (en) 1974-07-01 1975-07-08 Smithkline Corp Pseudodisaccharide intermediates
CS191047B1 (en) * 1977-09-05 1979-06-29 Alzbeta Krutosikova Ethylesters of 3-/5-aryl-2-furyl/-2-azidoacrylic acids and method for their preparing
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
CS276874B6 (en) * 1990-09-11 1992-08-12 Ustav Organicke Chemie A Bioch 1-(3-azido-2,3-dideoxy-beta-d-allocofuranosyl)thymine, process of its preparation and application
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
JPH08332095A (en) * 1995-06-06 1996-12-17 Chisso Corp Production of indenol

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