RU1827272C - Method of lung tuberculosis treatment - Google Patents

Abstract

Usage: in phthisiology. Summary of the invention: use is made of external laser irradiation with a gallium arsenide laser with a wavelength of 0.89 microns for 20-25 days. Benefit: reduces treatment time.

Description

The invention relates to medicine, namely to phthisiology

The purpose of the invention is to shorten the treatment time.

The method uses an external laser irradiation with a gallium arsenide laser pattern with a wavelength of 0.89 microns.

The course of laser treatment includes 20-25 daily procedures with an interval of 1-2 days and begins after 2-2.5 months of chemotherapy for patients with slow dynamics of destructive pulmonary tuberculosis. Laser irradiation is carried out from three points of the x-ray projection of the lesion.

The functional status of peripheral blood monocytes and neutrophils was assessed using the HCT test, which was placed with the cells at rest and after stimulation with their killed culture of BCG. The indicators of spontaneous and induced HCT tests, as well as the stimulation coefficient (CS), which are calculated as the ratio of the second indicator to the first, are taken into account.

Gallium arsenide laser operating mode Pattern wavelength 0 89 μm, average

radiation power 1 W, pulse repetition rate 80 Hz, exposure 4 min per field.

Laser exposure in the treatment of patients with pulmonary tuberculosis was carried out from 3 fields of an X-ray projection of a tuberculous site of inflammation in the lungs, i.e., laser beams were directed to a pathological process. Laser exposure points for localization of tuberculosis in the upper lobe of the right lung:

1) 3rd - intercostal space in the mid-clavicular line,

2) 3rd - intercostal space along the paravertebral line,

3) 3rd intercostal space in the mid-axillary line,

In the middle lobe of the right lung: 1) 5- intercostal space in the mid-clavicular line,

2) 6 - intercostal space along the paravertebral line.

3) 5 - intercostal space in the posterior axillary line.

In the lower lobe of the right lung

WITH

1) b-intercostal space in the mid-clavicular line, "

2) 6-intercostal space along the paravertebral line,

3) 6-intercostal space in the posterior axillary line,

In the upper lobe of the left, lung,

1} 2-intercostal space in the mid-clavicular line,

2} 3-intercostal space along the paravertebral line, w

, $ ZtLu for the mid-axillary (|

In the left lobe of the left lung:

1) 7-intercostal space of the anterior axillary line,

2) b-intercostal space along the paravertebral line,

3) 7-intercostal space along the axillary axial line.

Example 1. Patient T., 32 years old, diagnosis: infiltrative tuberculosis of the left lung in the decay phase, MBT +, pulmonary tuberculosis was detected for the first time. During the control X-ray examination after 2 months of chemotherapy, no noticeable dynamics of the specific process was established, and therefore, laser therapy was started. Before the start of laser therapy, the patient had a spontaneous HCT test of monocytes of 45.0, neutrophils - 39, and stimulated HCT tests of 175 and 131.2, respectively. After a course of laser irradiation during the control X-ray examination, the healing of the decay cavity was documented. The values of the spontaneous HCT test of monocytes were 23.8: neutrophils - 40.8, the values of the stimulated HCT test were 194.0 and 222.4, respectively. At the same time, the stimulation coefficient of monocytes increased from 3.8 to 8.1, neutrophils from 3.3 to 5.4.

0

5

0

5

0

5

0

Example 2. Patient Sh., 38 years old, diagnosis: cavernous tuberculosis of the upper lobe of the right lung in the phase of infiltration, MVT +. Tuberculosis is detected for the first time. After 2 months of chemotherapy under the conditions of the clinic of the institute, due to the slowed down dynamics of the process, laser therapy was prescribed. Before laser therapy, the spontaneous HCT test of monocytes was -91.5, neutrophils - 95.8; stimulated HCT test, respectively - 155.5 and 220.0. After a course of external laser irradiation, healing of the decay cavity was established against the background of chemotherapy. The value of the spontaneous HCT test of monocytes by this time decreased to 27.4, neutrophils to 68.1; indicators of the stimulated HCT test increased to 166.5, 330.0, respectively. At the same time, the stimulation coefficient of monocytes increased from 1.7 to 6.0, of neutrophils from 2.3 to 4.8.

The advantage of the proposed method: increasing the effectiveness of treatment of destructive pulmonary tuberculosis by 15-17%, reducing the duration of treatment for tuberculosis patients, minimally invasive method, short course of laser therapy, the absence of additional drug loading, the absence of side effects of laser irradiation, a narrow circle of contraindications.

Claims (1)

The claims A method of treating pulmonary tuberculosis, comprising administering drugs, characterized in that, in order to reduce the treatment time by increasing the functional activity of phagocytic cells, the skin is exposed to external radiation from three points of the x-ray projection of the lesion with a laser wavelength of 0.89 μm, pulse repetition rate of 80 Hz, duration - up to 4 min per field for 20-25 days.