RU1806740C - Method of controlling weak delivery in hyposthenic maternity patients - Google Patents

Abstract

Use: in obstetrics. The essence of the method: a selective B1-blocker, a cordanum at a dose of 40-50 mg per 200 ml of 5% glucose solution is administered dropwise, followed by a 2-2.5 IU increase in oxytocin per 200 ml of 5% glucose solution . Positive effect: reduces perinatal morbidity and mortality. 3 ill., 1 tab.

Description

The invention relates to medicine, namely to obstetrics.

An object of the invention is to increase the effectiveness of treatment for the prevention of complications.

The method is carried out as follows.

An ulnar vein puncture is performed. A dropper was set up for the simultaneous administration of drugs and, starting intravenously, from 8-10 drops in 1 minute (40-50 mg), a 5% glucose solution diluted in 200 ml was administered for 30-60 minutes and continued with insufficient effect. a gain of 2-25 IU of oxytocin per 300 ml of 5% glucose solution.

The method has been used in the treatment of 30 women in labor after sleep-rest with weakness of labor activity, which developed against the background of fatigue of the woman in labor.

A comparative analysis of the groups showed that the effect of the proposed method is higher than in the control group; the frequency of caesarean sections in connection with intrauterine hypoxia of the fetus decreased by 10%, intrauterine hypoxy and asphyxia of the fetus and newborn were 2.5 times in relation to the control group.

In FIG. 1-3, cardiohistograms of rhodostimulation with oxytocin, cordanum and oxytocin against the background of cordana are presented (Fig. 1 - stimulation with oxytocin; Fig. 2 - amplification by Bi-selective address blocker of cordanum; Fig. 3 - oxytocin amplification against the background of cordanum )

A comparative analysis of the delivery by the protop method and the proposed method for the treatment of labor weakness is given in the table.

Example 1. Pregnant, 27 years old, was admitted to the hospital with a diagnosis of Pregnancy II 40-41 weeks. Primary weakness of labor activity due to fatigue of the woman in labor.

After medical sleep-rest, a vaginal examination was carried out, With a vaginal examination it was established: the vagina of the woman giving birth, the neck is mat (L

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ki is shortened to 0.5 cm, soft, the cervical canal is open to 3-4 cm. The head is pressed to the entrance to the small pelvis. The fetal bladder is intact, functioning. Cape is not reached.

Menstrual function: menarche from 11 years old, established immediately, painless, moderate, 3 days after 29 days.

A woman has a history of only preterm delivery at 37 weeks.

Sizes of a basin: 25, 28, 30, 20.

Rhythmic fetal heartbeat: 136-138 beats / min.

The position of the fetus is longitudinal, before it lies, the head is pressed to the entrance to the small pelvis.

After sleep - rest of the bout for 20 s in 7-8 minutes. .

Due to the continuing weakness of labor after the intravenous administration of 40 mg of the selective RF adrenergic blocker of cordanum on 5% glucose of 200 ml within 1 h, normal labor was developed. Cramps began in 2-3 minutes for 30-25 s, and therefore, further administration of the cordanum gave birth to a boy weighing 3,800 kg with an Apgar rating of 8 points. After 5 minutes, the placenta with all the membranes separated and stood out. The crack of the back commissure is sutured. Total blood loss of 250 ml.

Example 2. Pregnant 23 years old was admitted with a diagnosis of Pregnancy first, 40 weeks. Childbirth 1. The primary weakness of labor is due to fatigue of the woman in childbirth.

The mother was given a medical, mental sleep rest for 4 hours.

When a vaginal examination was established: the vagina of a nulliparous woman, the cervix is flattened, the edges are thin supple, open by 3-4 cm. The fetal bladder is intact. Head on 1 plane of entry into the pelvis. Cape is not reached.

Menstrual function: menarche from 14 years old, established with, once, painless, moderate, 3-4 days after 27 days.

After sleep-rest, fights of weak strength appeared. Immediately after sleep-rest and intravenous administration, 50 mg of cordanum per 200 ml of 5% glucose was further strengthened by intravenous drip of 2.5 units of oxytocin per 300 ml of 5% glucose. After 20 minutes, the contractions began 20-230 s, with a frequency of 2-3 contractions for 10 minutes Tachysystole and uterine hypertonicity were not observed. After 9 hours from the onset of delivery, a full-term girl weighing 3,600 kg was born with an Apgar score of 9 points. After 20 minutes, the placenta separated and stood out. The placenta is intact, the shell is everything. The birth canal is whole, blood loss is 275 ml

It can be seen from the above examples that the use of oxytocin against the background of cordanum eliminates the toxic effect of oxytocin by reducing its dose from 50 ME to 25 ME in connection with the synergistic thermotonic effect of these drugs.

The proposed method allows to reduce the dose of oxytocin, which helps to reduce perinatal morbidity and mortality, and can be used in medical practice.

Claims (1)

The claims A method for treating labor weakness due to maternal fatigue, comprising administering drugs, characterized in that, in order to prevent complications, cordanum is administered in a dose of 4.0-5.0 mg intravenously 0 drop per 200 ml of 5% glucose solution, followed by the introduction of oxytocin 2.0-2.5 UNITS. 0 5 0 5 0 5 Birth complications Caesarean section in connection with insurmountable weakness of labor and intrauterine hypoxia of the fetus The threat of fetal asphyxiation of the fetus Asfixi of newborns Tachysystole and uterine hypertonicity prototype method (p-30) According to the proposed method (p-30) 1 (3.3%) 2 (8.7%) , yVfy-- p, , 5ff / / r / M / # ewyAfffi2ffffM.5m / m / 7M / f03a. about . . ptte.Z  i