RS65112B1 - Alprazolam for use in treating epilepsy - Google Patents

Alprazolam for use in treating epilepsy

Info

Publication number
RS65112B1
RS65112B1 RS20240089A RSP20240089A RS65112B1 RS 65112 B1 RS65112 B1 RS 65112B1 RS 20240089 A RS20240089 A RS 20240089A RS P20240089 A RSP20240089 A RS P20240089A RS 65112 B1 RS65112 B1 RS 65112B1
Authority
RS
Serbia
Prior art keywords
alprazolam
treating epilepsy
epilepsy
treating
Prior art date
Application number
RS20240089A
Other languages
Serbian (sr)
Inventor
James Cassella
Lily Gong
Edwin S Kamemoto
Original Assignee
Alexza Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexza Pharmaceuticals Inc filed Critical Alexza Pharmaceuticals Inc
Publication of RS65112B1 publication Critical patent/RS65112B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RS20240089A 2016-12-09 2017-12-08 Alprazolam for use in treating epilepsy RS65112B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662432353P 2016-12-09 2016-12-09
US201762485281P 2017-04-13 2017-04-13
EP17878604.2A EP3551189B1 (en) 2016-12-09 2017-12-08 Alprazolam for use in treating epilepsy
PCT/US2017/065347 WO2018107045A1 (en) 2016-12-09 2017-12-08 Method of treating epilepsy

Publications (1)

Publication Number Publication Date
RS65112B1 true RS65112B1 (en) 2024-02-29

Family

ID=62492165

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20240089A RS65112B1 (en) 2016-12-09 2017-12-08 Alprazolam for use in treating epilepsy

Country Status (20)

Country Link
US (2) US11241383B2 (en)
EP (2) EP3551189B1 (en)
JP (3) JP7379154B2 (en)
KR (3) KR20230066655A (en)
CN (2) CN116172985A (en)
AU (3) AU2017370747A1 (en)
CA (1) CA3046385C (en)
DK (1) DK3551189T3 (en)
ES (1) ES2968097T3 (en)
FI (1) FI3551189T3 (en)
HR (1) HRP20240106T1 (en)
HU (1) HUE064864T2 (en)
IL (1) IL267199A (en)
LT (1) LT3551189T (en)
MX (2) MX2019006745A (en)
PL (1) PL3551189T3 (en)
PT (1) PT3551189T (en)
RS (1) RS65112B1 (en)
SI (1) SI3551189T1 (en)
WO (1) WO2018107045A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US20120048963A1 (en) 2010-08-26 2012-03-01 Alexza Pharmaceuticals, Inc. Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter
KR102581975B1 (en) 2015-03-11 2023-09-25 알렉스자 파마스티칼즈, 인크. Use of antistatic materials in the airway for thermal aerosol condensation process
SI3551189T1 (en) 2016-12-09 2024-03-29 Alexza Pharmaceuticals, Inc. Alprazolam for use in treating epilepsy
JP7150887B2 (en) * 2018-06-14 2022-10-11 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム Aerosol generator with planar heater

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987052A (en) 1969-03-17 1976-10-19 The Upjohn Company 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines
AU2001284158B2 (en) * 2000-08-18 2004-03-25 Norton Healthcare, Ltd. Spray device
US6613308B2 (en) * 2000-09-19 2003-09-02 Advanced Inhalation Research, Inc. Pulmonary delivery in treating disorders of the central nervous system
DE60230035D1 (en) 2001-05-24 2009-01-08 Alexza Pharmaceuticals Inc ADMINISTRATION OF ALPRAZOLAM, ESTAZOLAM, MIDAZOLAM OR TRIAZOLAM BY INHALATION
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
EP1392260A2 (en) * 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Delivery of benzodiazepines through an inhalation route
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7078016B2 (en) 2001-11-21 2006-07-18 Alexza Pharmaceuticals, Inc. Delivery of caffeine through an inhalation route
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20080038363A1 (en) 2001-05-24 2008-02-14 Zaffaroni Alejandro C Aerosol delivery system and uses thereof
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US20030118512A1 (en) 2001-10-30 2003-06-26 Shen William W. Volatilization of a drug from an inclusion complex
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US20030138508A1 (en) 2001-12-18 2003-07-24 Novack Gary D. Method for administering an analgesic
US7498019B2 (en) 2001-05-24 2009-03-03 Alexza Pharmaceuticals, Inc. Delivery of compounds for the treatment of headache through an inhalation route
US6759029B2 (en) 2001-05-24 2004-07-06 Alexza Molecular Delivery Corporation Delivery of rizatriptan and zolmitriptan through an inhalation route
WO2003041693A1 (en) 2001-11-09 2003-05-22 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
EP1455875A2 (en) 2001-11-21 2004-09-15 Alexza Molecular Delivery Corporation Open-celled substrates for drug delivery
AU2003228907A1 (en) 2002-05-07 2003-11-11 Nektar Therapeutics Capsules for dry powder inhalers and methods of making and using same
CA2483687A1 (en) 2002-05-13 2003-11-20 Alexza Molecular Delivery Corporation Delivery of drug amines through an inhalation route
US20060193788A1 (en) 2002-11-26 2006-08-31 Hale Ron L Acute treatment of headache with phenothiazine antipsychotics
EP1565184A1 (en) 2002-11-26 2005-08-24 Alexza Molecular Delivery Corporation Treatment of headache with antipsychotics delivered by inhalation
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7550133B2 (en) 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
ATE420647T1 (en) 2002-11-26 2009-01-15 Alexza Pharmaceuticals Inc USE OF LOXAPINE FOR THE PRODUCTION OF A PAIN TREATMENT AGENT
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
EP1625335A2 (en) 2003-05-21 2006-02-15 Alexza Pharmaceuticals, Inc. Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
JP4869927B2 (en) 2003-08-04 2012-02-08 アレックザ ファーマシューティカルズ, インコーポレイテッド Substrates and preparation methods and uses for drug delivery devices
WO2005014090A1 (en) 2003-08-04 2005-02-17 Alexza Pharmaceuticals, Inc. Methods of determining film thicknesses for an aerosol delivery article
US20050126562A1 (en) 2003-12-15 2005-06-16 Alexza Molecular Delivery Corporation Treatment of breakthrough pain by drug aerosol inhalation
WO2005059804A2 (en) 2003-12-16 2005-06-30 Alexza Pharmaceuticals, Inc. Methods for monitoring severity of panic attacks and other rapidly evolving medical events in real-time
US7402777B2 (en) 2004-05-20 2008-07-22 Alexza Pharmaceuticals, Inc. Stable initiator compositions and igniters
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US20060032496A1 (en) 2004-08-12 2006-02-16 Alexza Molecular Delivery Corporation Inhalation actuated percussive ignition system
WO2006022714A1 (en) 2004-08-12 2006-03-02 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
US20100006092A1 (en) 2004-08-12 2010-01-14 Alexza Pharmaceuticals, Inc. Aerosol Drug Delivery Device Incorporating Percussively Activated Heat Packages
WO2006044421A2 (en) 2004-10-12 2006-04-27 Alexza Pharmaceuticals, Inc. Cardiac safe, rapid medication delivery
EP2353590A1 (en) 2005-02-15 2011-08-10 Elan Pharma International Limited Aerosol and injectable formulations of nanoparticulate benzodiazepine
KR101405545B1 (en) * 2005-11-28 2014-07-03 마리누스 파마슈티컬스 Ganaxolone formulations and methods for the making and use thereof
US7494344B2 (en) 2005-12-29 2009-02-24 Molex Incorporated Heating element connector assembly with press-fit terminals
WO2008080170A1 (en) 2006-12-22 2008-07-03 Alexza Pharmaceuticals, Inc. Mixed drug aerosol compositiions
US7513781B2 (en) 2006-12-27 2009-04-07 Molex Incorporated Heating element connector assembly with insert molded strips
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
WO2008134668A2 (en) 2007-04-27 2008-11-06 Alexza Pharmaceuticals, Inc. Heat-labile prodrugs
US20080279784A1 (en) 2007-05-07 2008-11-13 Questcor Pharmaceuticals, Inc. Nasal administration of benzodiazepines
WO2009089550A1 (en) 2008-01-11 2009-07-16 Alexza Pharmaceuticals, Inc. Metal coordination complexes of volatile drugs
EP2307035B1 (en) * 2008-05-16 2013-12-04 NoNO Inc. Use of an inhibitor of psd-95treatment for epilepsy
US7834295B2 (en) 2008-09-16 2010-11-16 Alexza Pharmaceuticals, Inc. Printable igniters
US20100068155A1 (en) 2008-09-16 2010-03-18 Alexza Pharmaceuticals, Inc. Reactant Formulations and Methods for Controlled Heating
US20100065052A1 (en) 2008-09-16 2010-03-18 Alexza Pharmaceuticals, Inc. Heating Units
US20100300433A1 (en) 2009-05-28 2010-12-02 Alexza Pharmaceuticals, Inc. Substrates for Enhancing Purity or Yield of Compounds Forming a Condensation Aerosol
US20100181387A1 (en) * 2009-12-01 2010-07-22 Zaffaroni Alejandro C Aerosol delivery system and uses thereof
US20120048963A1 (en) 2010-08-26 2012-03-01 Alexza Pharmaceuticals, Inc. Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter
US20130309306A1 (en) 2010-12-01 2013-11-21 The Regents Of The University Of California Intrapulmonary benzodiazepine for the treatment and prevention of seizures
AU2011335415B2 (en) * 2010-12-02 2016-05-19 Ucb Pharma Gmbh Once daily formulation of lacosamide
CN103796656A (en) 2011-06-14 2014-05-14 哈尔生物药投资有限责任公司 Administration of benzodiazepine
EP2794577A4 (en) 2011-12-20 2015-05-20 Map Pharmaceuticals Inc Excipient-free aerosol formulation
JP6397493B2 (en) 2013-07-11 2018-09-26 アレックザ ファーマシューティカルズ, インコーポレイテッド Nicotine salt with meta-salicylic acid
KR102581975B1 (en) 2015-03-11 2023-09-25 알렉스자 파마스티칼즈, 인크. Use of antistatic materials in the airway for thermal aerosol condensation process
SI3551189T1 (en) 2016-12-09 2024-03-29 Alexza Pharmaceuticals, Inc. Alprazolam for use in treating epilepsy

Also Published As

Publication number Publication date
CN110267662A (en) 2019-09-20
JP2020500911A (en) 2020-01-16
AU2017370747A1 (en) 2019-06-27
JP2023118696A (en) 2023-08-25
EP3551189B1 (en) 2023-11-01
US20210244661A1 (en) 2021-08-12
HUE064864T2 (en) 2024-04-28
EP4272827A2 (en) 2023-11-08
ES2968097T3 (en) 2024-05-07
MX2022008775A (en) 2022-07-27
US20190307680A1 (en) 2019-10-10
KR20230066655A (en) 2023-05-16
US20220241191A1 (en) 2022-08-04
JP7379154B2 (en) 2023-11-14
CN116172985A (en) 2023-05-30
JP7376532B2 (en) 2023-11-08
AU2021202621A1 (en) 2021-05-27
CA3046385A1 (en) 2018-06-14
PT3551189T (en) 2024-01-22
CA3046385C (en) 2023-12-19
AU2022287583A1 (en) 2023-02-02
AU2021202621B2 (en) 2022-09-15
EP3551189A1 (en) 2019-10-16
MX2019006745A (en) 2019-10-14
IL267199A (en) 2019-08-29
US11717479B2 (en) 2023-08-08
DK3551189T3 (en) 2024-01-29
KR20190104531A (en) 2019-09-10
JP2021154135A (en) 2021-10-07
EP3551189A4 (en) 2020-07-22
EP4272827A3 (en) 2024-01-24
FI3551189T3 (en) 2024-01-31
HRP20240106T1 (en) 2024-04-12
PL3551189T3 (en) 2024-04-22
US11241383B2 (en) 2022-02-08
KR20220164620A (en) 2022-12-13
WO2018107045A1 (en) 2018-06-14
SI3551189T1 (en) 2024-03-29
LT3551189T (en) 2024-02-12

Similar Documents

Publication Publication Date Title
HK1253580A1 (en) Use of cannabinoids in the treatment of epilepsy
IL259795A (en) Methods and compositions for treating a serpinc1-associated disorder
HK1244686A1 (en) Pancreatitis treatment
PT3334422T (en) Use of cannabinoids in the treatment of epilepsy
IL272596A (en) Pridopidine for use in treating als
IL259992B (en) Compounds for use in methods for treating hyperalgesia
SI3307296T1 (en) Timp2 for use in treating aging-associated conditions
HK1244217A1 (en) Methods for treating proteinopathies
HK1251965A1 (en) Methods for treating epilepsy
RS65112B1 (en) Alprazolam for use in treating epilepsy
EP3736275C0 (en) Oxabicycloheptane prodrugs for use in treating cancer
HUE058645T2 (en) Medicament for use in treating gout
SG11201710686PA (en) Hair treatment agent
IL259358A (en) Bis-pyridazine compounds and their use in treating cancer
IL246637A0 (en) Compositions and methods for treating intracerebral hemorrhage
GB201400311D0 (en) Treating Susceptibility
SG11201804140PA (en) Acidic-gas treating agent and acidic-gas treating method
GB201702652D0 (en) Delta-theraphotoxin-Ac1 for use in treating diabetes
GB201510764D0 (en) bis-Pyridazine compounds and their use in treating cancer
GB201511503D0 (en) Finishing treatment
GB201500572D0 (en) Sanding apparatus
GB201411111D0 (en) bis-Pyridazine compounds and their use in treating cancer