RS59577B1 - Metode za smanjenje agregacije glikoproteina - Google Patents

Metode za smanjenje agregacije glikoproteina

Info

Publication number
RS59577B1
RS59577B1 RS20191478A RSP20191478A RS59577B1 RS 59577 B1 RS59577 B1 RS 59577B1 RS 20191478 A RS20191478 A RS 20191478A RS P20191478 A RSP20191478 A RS P20191478A RS 59577 B1 RS59577 B1 RS 59577B1
Authority
RS
Serbia
Prior art keywords
methods
aggregation
reducing glycoprotein
reducing
glycoprotein aggregation
Prior art date
Application number
RS20191478A
Other languages
English (en)
Inventor
Yueming Qian
Sarwat F Khattak
Zhengjian Li
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of RS59577B1 publication Critical patent/RS59577B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
RS20191478A 2012-06-29 2013-06-27 Metode za smanjenje agregacije glikoproteina RS59577B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261666296P 2012-06-29 2012-06-29
US201361839393P 2013-06-26 2013-06-26
EP13734632.6A EP2867251B1 (en) 2012-06-29 2013-06-27 Methods for reducing glycoprotein aggregation
PCT/US2013/048105 WO2014004780A1 (en) 2012-06-29 2013-06-27 Methods for reducing glycoprotein aggregation

Publications (1)

Publication Number Publication Date
RS59577B1 true RS59577B1 (sr) 2019-12-31

Family

ID=48747805

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20191478A RS59577B1 (sr) 2012-06-29 2013-06-27 Metode za smanjenje agregacije glikoproteina

Country Status (15)

Country Link
US (1) US9926365B2 (sr)
EP (2) EP2867251B1 (sr)
JP (2) JP2015522024A (sr)
CN (1) CN104520316B (sr)
CY (1) CY1122376T1 (sr)
DK (1) DK2867251T3 (sr)
ES (1) ES2753150T3 (sr)
HR (1) HRP20192084T1 (sr)
HU (1) HUE047077T2 (sr)
LT (1) LT2867251T (sr)
PL (1) PL2867251T3 (sr)
PT (1) PT2867251T (sr)
RS (1) RS59577B1 (sr)
SI (1) SI2867251T1 (sr)
WO (1) WO2014004780A1 (sr)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU675422B2 (en) * 1992-02-05 1997-02-06 David Richard Light Protease-resistant thrombomodulin analogs
US7094874B2 (en) 2000-05-26 2006-08-22 Bristol-Myers Squibb Co. Soluble CTLA4 mutant molecules
JP2004513878A (ja) * 2000-06-23 2004-05-13 マキシジェン, インコーポレイテッド 新規同時刺激分子
EP1299415A4 (en) * 2000-07-12 2005-01-19 Gryphon Therapeutics Inc MODULATOR OF THE CHEMOKINE RECEPTOR, PRODUCTION AND USE THEREOF
US20030054354A1 (en) * 2001-08-23 2003-03-20 Bennett C. Frank Use of antisense oligonucleotide libraries for identifying gene function
EP1581631A4 (en) 2002-10-01 2007-09-05 Xencor Inc INTERFERON VARIANTS HAVING IMPROVED PROPERTIES
CA2508925C (en) 2002-12-23 2012-08-28 Bristol-Myers Squibb Company Product quality enhancement in mammalian cell culture processes for protein production
WO2004058800A2 (en) 2002-12-23 2004-07-15 Bristol-Myers Squibb Company Mammalian cell culture processes for protein production
CA2520097C (en) * 2003-03-28 2014-10-07 Biogen Idec Ma Inc. Truncated baff receptors
SI1969007T1 (sl) * 2005-12-20 2014-03-31 Bristol-Myers Squibb Company Sestavki in postopki za izdelavo sestavka
TW200738261A (en) 2005-12-20 2007-10-16 Bristol Myers Squibb Co Stable protein formulations
CN101448852A (zh) * 2005-12-20 2009-06-03 布里斯托尔—迈尔斯斯奎布公司 组合物和用于生产组合物的方法
CA2687117A1 (en) * 2007-05-14 2008-11-27 Biogen Idec Ma Inc. Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto
AU2010206681A1 (en) * 2009-01-23 2011-09-01 Biogen Idec Ma Inc. Stabilized Fc polypeptides with reduced effector function and methods of use
SG175716A1 (en) * 2009-05-07 2011-12-29 Novozymes Biopharma Dk As Method of controlling o-linked glycosylation of antibodies
US9540426B2 (en) * 2009-10-06 2017-01-10 Bristol-Myers Squibb Company Mammalian cell culture processes for protein production
WO2012170938A1 (en) 2011-06-08 2012-12-13 Acceleron Pharma Inc. Compositions and methods for increasing serum half-life
KR102133060B1 (ko) * 2012-05-11 2020-07-10 메디뮨 리미티드 Ctla-4 변이체

Also Published As

Publication number Publication date
HUE047077T2 (hu) 2020-04-28
PL2867251T3 (pl) 2020-03-31
JP2018057387A (ja) 2018-04-12
CY1122376T1 (el) 2021-01-27
US9926365B2 (en) 2018-03-27
PT2867251T (pt) 2019-11-11
SI2867251T1 (sl) 2019-12-31
WO2014004780A1 (en) 2014-01-03
ES2753150T3 (es) 2020-04-07
US20150322139A1 (en) 2015-11-12
HRP20192084T1 (hr) 2020-02-21
EP3613763A1 (en) 2020-02-26
DK2867251T3 (da) 2019-11-25
CN104520316A (zh) 2015-04-15
JP2015522024A (ja) 2015-08-03
LT2867251T (lt) 2019-11-25
CN104520316B (zh) 2021-07-06
EP2867251A1 (en) 2015-05-06
EP2867251B1 (en) 2019-08-21

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