RS58976B1 - Antiamiloidna jedinjenja koja sadrže benzofuran - Google Patents

Antiamiloidna jedinjenja koja sadrže benzofuran

Info

Publication number
RS58976B1
RS58976B1 RS20190884A RSP20190884A RS58976B1 RS 58976 B1 RS58976 B1 RS 58976B1 RS 20190884 A RS20190884 A RS 20190884A RS P20190884 A RSP20190884 A RS P20190884A RS 58976 B1 RS58976 B1 RS 58976B1
Authority
RS
Serbia
Prior art keywords
benzofurazan
compounds containing
amyloid compounds
amyloid
containing benzofurazan
Prior art date
Application number
RS20190884A
Other languages
English (en)
Inventor
Mark A Reed
Thomas K Wood
Scott C Banfield
Christopher J Barden
Arun Yadav
Erhu Lu
Fan Wu
Original Assignee
Treventis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Treventis Corp filed Critical Treventis Corp
Publication of RS58976B1 publication Critical patent/RS58976B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/081,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
RS20190884A 2014-02-27 2015-02-27 Antiamiloidna jedinjenja koja sadrže benzofuran RS58976B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461945697P 2014-02-27 2014-02-27
PCT/US2015/017939 WO2015131021A2 (en) 2014-02-27 2015-02-27 Anti-amyloid compounds containing benzofurazan
EP15755943.6A EP3110812B1 (en) 2014-02-27 2015-02-27 Anti-amyloid compounds containing benzofurazan

Publications (1)

Publication Number Publication Date
RS58976B1 true RS58976B1 (sr) 2019-08-30

Family

ID=54009787

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20190884A RS58976B1 (sr) 2014-02-27 2015-02-27 Antiamiloidna jedinjenja koja sadrže benzofuran

Country Status (18)

Country Link
US (1) US9938249B2 (sr)
EP (1) EP3110812B1 (sr)
JP (1) JP6663361B2 (sr)
AU (1) AU2015222903B2 (sr)
CA (1) CA2977360C (sr)
CY (1) CY1121827T1 (sr)
DK (1) DK3110812T3 (sr)
ES (1) ES2734432T3 (sr)
HR (1) HRP20191150T1 (sr)
HU (1) HUE044999T2 (sr)
IL (1) IL247428B (sr)
LT (1) LT3110812T (sr)
PL (1) PL3110812T3 (sr)
PT (1) PT3110812T (sr)
RS (1) RS58976B1 (sr)
SI (1) SI3110812T1 (sr)
TR (1) TR201910291T4 (sr)
WO (1) WO2015131021A2 (sr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19643037A1 (de) 1996-10-18 1998-04-23 Boehringer Ingelheim Kg Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
MXPA04004443A (es) 2001-11-14 2004-08-11 Merck Patent Gmbh Derivados de pirazol.
US20050282818A1 (en) * 2004-06-22 2005-12-22 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
ES2650744T3 (es) * 2010-12-14 2018-01-22 Electrophoretics Limited Inhibidores de la caseína quinasa 1 delta (CK1delta)
MX365851B (es) * 2012-08-24 2019-06-17 Treventis Corp Compuestos de benzofurazano anti-amiloides y metodos.

Also Published As

Publication number Publication date
PT3110812T (pt) 2019-07-10
HRP20191150T1 (hr) 2019-10-04
ES2734432T3 (es) 2019-12-05
HUE044999T2 (hu) 2019-12-30
JP2017506674A (ja) 2017-03-09
WO2015131021A2 (en) 2015-09-03
JP6663361B2 (ja) 2020-03-11
AU2015222903B2 (en) 2018-02-01
CA2977360C (en) 2022-09-27
TR201910291T4 (tr) 2019-07-22
US9938249B2 (en) 2018-04-10
PL3110812T3 (pl) 2019-10-31
IL247428A0 (en) 2016-11-30
SI3110812T1 (sl) 2019-08-30
LT3110812T (lt) 2019-07-10
CY1121827T1 (el) 2020-07-31
US20170174641A1 (en) 2017-06-22
AU2015222903A1 (en) 2016-10-06
EP3110812A4 (en) 2017-07-05
EP3110812A2 (en) 2017-01-04
WO2015131021A3 (en) 2015-11-19
IL247428B (en) 2020-01-30
DK3110812T3 (da) 2019-07-08
EP3110812B1 (en) 2019-04-10
CA2977360A1 (en) 2015-09-03

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