Jedinjenje opšte formule Ia ili lbnaznačeno time štoR1 je metil, hloro, bromo ili metoksi;R2 je hloro ili metil;R3 predstavlja C1-6alkil, C2-6alkenil, C2-6alkinil, C1-6hidroksialkil, C1-6haloalkil, C1-6alkoksi, C1-6alkoksikarbonil, C1-6amino, ureido, tioureido, C1-6alkilkarboniloksi, C1-6alkilkarbonil, C1-6alkoksikarboniloksi, C1-6alkoksisulfoniloksi, C1-6alkoksikarbamoil ili C1-6aminokarbonil,pri čemu je svaki od njih izborno supstituisan sa jednim ili više, istih ili različitih supstituenata izabranih iz grupe koju čine halogen, hidroksi, merkapto, trifluorometil, cijano, karboksi, CONH2, nitro, okso, -S(O)2NH2, C1-4alkil, C2-4alkenil, C2-4alkinil, C1-4hidroksialkil, C1-6haloalkil, C1-4alkoksi, C1-4alkoksikarbonil, ureido, tioureido, C1-4alkilkarboniloksi, C1-4alkoksikarboniloksi, C1-4alkoksisulfoniloksi, C1-4alkoksikarbamoil, C1-4aminokarbonil, C1-4alkiltio, C3-6cikloalkil, C3-6cikloalkenil, amino, imino, C1-4aminosulfonil, C1-4aminokarboniloksi, C1-4alkilsulfonilamino, C1-4alkoksiimino, C1-4alkilkarbonilamino, C1-4alkilsulfonil, C1-6heteroaril, C1-6heterocikloalkil ili C2-6heterocikloalkenil,pri čemu su navedeni C1-4alkil, C2-4alkenil, C2-4alkinil, C1-4hidroksialkil, C1-6haloalkil, C1-4alkoksi, C1-4alkoksikarbonil, ureido, tioureido, C1-4alkilkarboniloksi, C1-4alkoksikarboniloksi, C1-4alkoksisulfoniloksi, C1-4alkoksikarbamoil, C1-4aminokarbonil, C1-4alkiltio, C3-6cikloalkil, C3-C6cikloalkenil, amino, imino, C1-4aminosulfonil, C1-4aminokarboniloksi, C1-4alkilsulfonilamino, C1-4alkoksiimino, C1-4alkilkarbonilamino, C1-4alkilsulfonil, C1-6heteroaril, C1-6heterocikloalkil ili C2-6heterocikloalkenil, izborno dodatno supstituisani sa jednim ili više, istih ili različitih supstituenata izabranih iz grupe koju čine halogen, hidroksi, -NH2, merkapto, trifluorometil, cijano, karboksi, CONH2, nitro, okso, -S(O)2NH2, C1-4alkil ili C1-4hidroksialkil,ili R3 predstavlja vodonik, hidroksi ili karboksi;R4, R5, R6, R7 i R8 međusobno nezavisno predstavljaju vodonik, halogen, -NH2, hidroksi, trifluorometil, metoksi, etoksi, cijano, acetil, acetamido, metil ili etil;uz uslov da jedinjenje nije [4-(2-aminofenil)amino)-2-hlorofenil]-[2-metil-5-[l-[2-[(tetrahidro-2H-piran-2-il)oksi]etil]-lH-l,2,3-triazol-4-il]-fenil]-metanon ili [4-[(2-aminofenil)amino] -2-hlorofenil] - [5 - [ 1 -(2-hidroksietil)-1H-1,2,3 -triazol-4-il] -2-metilfenil] -metanon;ili njegova farmaceutski prihvatljiva so ili rastvor.Prijava sadrži još 25 zavisnih patentnih zahteva.A compound of general formula Ia or Ib wherein R1 is methyl, chloro, bromo or methoxy; R2 is chloro or methyl; R3 is C1-6alkyl, C2-6alkenyl, C2-6alkynyl, C1-6haloalkyl, C1-6alkoxy, C1 -6alkoxycarbonyl, C1-6amino, ureido, thioureido, C1-6alkylcarbonyloxy, C1-6alkylcarbonyl, C1-6alkoxycarbonyloxy, C1-6alkoxysulfonyloxy, C1-6alkoxycarbamoyl or C1-6aminocarbonyl, each of which is optionally or optionally substituted by one or more substituents thereof various substituents selected from the group consisting of halogen, hydroxy, mercapto, trifluoromethyl, cyano, carboxy, CONH2, nitro, oxo, -S (O) 2NH2, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C1-4hydroxyalkyl, C1- 6haloalkyl, C 1-4 alkoxy, C 1-4 alkoxycarbonyl, ureido, thioureido, C 1-4 alkylcarbonyloxy, C 1-4 alkoxycarbonyloxy, C 1-4 alkoxysulfonyloxy, C 1-4 alkoxycarbamoyl, C 1-4 aminocarbonyl, C 1-4 alkylthio, C 3-6 cycloalkyl, C 3-6 cycloalkyl, C 3-6 cycloalkyl, C 3-6 cycloalkyl, C 3-6 cycloalkyl, C 3-6 C1-4aminosulfonyl, C1-4aminocarbonyloxy, C1-4alkylsulfonylamino, C1-4a alkoxyimino, C1-4alkylcarbonylamino, C1-4alkylsulfonyl, C1-6heteroaryl, C1-6heterocycloalkyl or C2-6heterocycloalkenyl, with C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C1-4hydroxyalkyl, C1-6alkyloxy, C1-4alkylalkyl C 1-4 alkoxycarbonyl, ureido, thioureido, C 1-4 alkylcarbonyloxy, C 1-4 alkoxycarbonyloxy, C 1-4 alkoxysulfonyloxy, C 1-4 alkoxycarbamoyl, C 1-4 aminocarbonyl, C 1-4 alkylthio, C 3-6 cycloalkyl, C 3 -C 6 cycloalkenyl, amino-C1 imino sulfonyl 4aminocarbonyloxy, C 1-4 alkylsulfonylamino, C 1-4 alkoxyimino, C 1-4 alkylcarbonylamino, C 1-4 alkylsulfonyl, C 1-6 heteroaryl, C 1-6 heterocycloalkyl or C 2-6 heterocycloalkenyl optionally additionally substituted with one or more, same or different hydroxy substituents , -NH2, mercapto, trifluoromethyl, cyano, carboxy, CONH2, nitro, oxo, -S (O) 2NH2, C1-4alkyl or C1-4hydroxyalkyl, or R3 represents hydrogen, hydroxy or carboxy; R4, R5, R6, R7 and R8 independently of one another are hydrogen, h allogene, -NH2, hydroxy, trifluoromethyl, methoxy, ethoxy, cyano, acetyl, acetamido, methyl or ethyl, provided the compound is not [4- (2-aminophenyl) amino) -2-chlorophenyl] - [2-methyl-5 - [1- [2 - [(tetrahydro-2H-pyran-2-yl) oxy] ethyl] -1H-1,2,3-triazol-4-yl] -phenyl] -methanone or [4 - [(2 -aminophenyl) amino] -2-chlorophenyl] - [5- [1- (2-hydroxyethyl) -1H-1,2,3-triazol-4-yl] -2-methylphenyl] -methanone; or a pharmaceutically acceptable salt thereof or solution.The application contains another 25 dependent claims.