RS49716B - A novel therapeutic anti- inflamatory and analgesic composition containing nimesulide for use transdermally and process for the manufacture thereof - Google Patents
A novel therapeutic anti- inflamatory and analgesic composition containing nimesulide for use transdermally and process for the manufacture thereofInfo
- Publication number
- RS49716B RS49716B YUP-338/96A YU33896A RS49716B RS 49716 B RS49716 B RS 49716B YU 33896 A YU33896 A YU 33896A RS 49716 B RS49716 B RS 49716B
- Authority
- RS
- Serbia
- Prior art keywords
- base
- carrier
- pyrrolidone
- therapeutic anti
- percutaneous
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Nova terapeutska anti-inflamatorna i analgetska farmaceutska kompozicija za lokalnu primenu, naznačena time, što sadrži nimesulid u opsegu od 0.1% do 10% m/m i nosač/osnovu koja pojačava perkutanoznu apsorpciju, u količini od 90% do 99.9% m/m, pri čemu pomenuti prekutanozno pojačavajući nosač/osnova deluje kao prekoncentrat mikronosača ili mikronosač i sadrži prekutanozni pojačavač u količini od 0.5% do 60% m/m koji se bira iz grupe koja se sastoji od vakcenske, cis-vakcenske, linolne, linolenske, elaidinske, oleinske, pretroselinske, erurične ili nervonske kiseline i/ili od bilo kog od njima odgovarajućih alkohola, ili 1-dodecilazacikloheptan-2-ona; ili od sulfoksida kao što je dimetilsulfoksid, n-decil metilsulfoksid; ili dimetilacetamida, dimetilformamida i N,N-dietil-toluamida; ili pirolidona kao što su 2-pirolidon i N-metil-2 pirolidon; i pri čemu pomenuti perkutanozno pojačavajući nosač/baza sadrži površinski aktivno sredstvo od 0.0% do 12% m/m, sredstvo za želiranje/zgrušnjavanje od 0.2% do 19% m/m i jedan ili više nosača/osnova od 5% do 97% m/m, gde pomenuti nosač/osnova sadrži vodu od 1% do 15% m/m.- Prijava sadrži još 9 patentnih zahteva.A new topical therapeutic anti-inflammatory and analgesic pharmaceutical composition comprising nimesulide in the range of 0.1% to 10% w / w carrier / base that enhances percutaneous absorption in an amount of 90% to 99.9% w / w. wherein said percutaneous enhancer carrier / base acts as a microcarrier preconcentrate or microcarrier and comprises a percutaneous enhancer in an amount of 0.5% to 60% w / w selected from the group consisting of vaccine, cis-vaccine, linoleic, linolenic, elaidine, oleic, pretroselinic, eruric or nervous acids and / or any of the corresponding alcohols, or 1-dodecylazacycloheptan-2-one; or from sulfoxides such as dimethylsulfoxide, n-decyl methylsulfoxide; or dimethylacetamide, dimethylformamide and N, N-diethyl-toluamide; or pyrrolidone such as 2-pyrrolidone and N-methyl-2 pyrrolidone; and wherein said percutaneous enhancer carrier / base comprises a surfactant of 0.0% to 12% w / w, a gelling / clotting agent of 0.2% to 19% w / w, or one or more carriers / base of 5% to 97% w / w / m, where said carrier / base contains water from 1% to 15% m / m. - The application contains 9 more claims.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1389DE1995 | 1995-07-25 | ||
| IN2048DE1995 IN186558B (en) | 1995-07-25 | 1995-11-08 | |
| IN2047DE1995 | 1995-11-08 | ||
| IN2046DE1995 | 1995-11-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU33896A YU33896A (en) | 1999-03-04 |
| RS49716B true RS49716B (en) | 2007-12-31 |
Family
ID=40929802
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-339/96A RS49717B (en) | 1995-07-25 | 1996-06-05 | Therapeutic injectable analgesic pharmaceutical composition containing nimesulide for intra- muscular administration and process for the manufacture thereof |
| YUP-338/96A RS49716B (en) | 1995-07-25 | 1996-06-05 | A novel therapeutic anti- inflamatory and analgesic composition containing nimesulide for use transdermally and process for the manufacture thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-339/96A RS49717B (en) | 1995-07-25 | 1996-06-05 | Therapeutic injectable analgesic pharmaceutical composition containing nimesulide for intra- muscular administration and process for the manufacture thereof |
Country Status (4)
| Country | Link |
|---|---|
| CO (2) | CO4520276A1 (en) |
| MY (1) | MY133741A (en) |
| RS (2) | RS49717B (en) |
| UA (2) | UA41974C2 (en) |
-
1996
- 1996-06-05 RS YUP-339/96A patent/RS49717B/en unknown
- 1996-06-05 RS YUP-338/96A patent/RS49716B/en unknown
- 1996-06-06 CO CO96029489A patent/CO4520276A1/en unknown
- 1996-06-06 CO CO96029490A patent/CO4520277A1/en unknown
- 1996-06-20 MY MYPI96002493A patent/MY133741A/en unknown
- 1996-07-19 UA UA96072922A patent/UA41974C2/en unknown
- 1996-07-19 UA UA96072921A patent/UA41973C2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS49717B (en) | 2007-12-31 |
| CO4520277A1 (en) | 1997-10-15 |
| YU33896A (en) | 1999-03-04 |
| YU33996A (en) | 1999-03-04 |
| CO4520276A1 (en) | 1997-10-15 |
| UA41974C2 (en) | 2001-10-15 |
| MY133741A (en) | 2007-11-30 |
| UA41973C2 (en) | 2001-10-15 |
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