RS20100352A2 - Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone - Google Patents

Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

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Publication number
RS20100352A2
RS20100352A2 RS20100352A RSP20100352A RS20100352A2 RS 20100352 A2 RS20100352 A2 RS 20100352A2 RS 20100352 A RS20100352 A RS 20100352A RS P20100352 A RSP20100352 A RS P20100352A RS 20100352 A2 RS20100352 A2 RS 20100352A2
Authority
RS
Serbia
Prior art keywords
pyrrolidinone
phenyl
carbamoylmethyl
preparation
pharmacologically active
Prior art date
Application number
RS20100352A
Other languages
Serbian (sr)
Inventor
Grigory Veinberg
Maksim Vorona
Liga Zvejniece
Aleksandrs Chernobrovijs
Ivars Kalvinsh
Original Assignee
Akciju Sabiedriba "Olainfarm"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akciju Sabiedriba "Olainfarm" filed Critical Akciju Sabiedriba "Olainfarm"
Priority to RS20100352A priority Critical patent/RS20100352A3/en
Publication of RS20100352A2 publication Critical patent/RS20100352A2/en
Publication of RS20100352A3 publication Critical patent/RS20100352A3/en

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  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Invention herewith described refers to the R-enantiomer of N-carbamoylmethyl-4-phenyl-2-pyrrolidinone (R-Carphedon) of pharmacological value. The method of its preparation includes compounds (I) according to claim 1 with N-alkylation of 4(R)-phenyl-2-pyrrolidinone with ethyl bromoacetate which is followed by the carbamoylation of the intermediate N-ethoxycarbonylmethyl-4(R)-aryl-2-pyrrolidinone with ammonia.
RS20100352A 2010-08-06 2010-08-06 Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone RS20100352A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RS20100352A RS20100352A3 (en) 2010-08-06 2010-08-06 Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RS20100352A RS20100352A3 (en) 2010-08-06 2010-08-06 Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

Publications (2)

Publication Number Publication Date
RS20100352A2 true RS20100352A2 (en) 2012-02-29
RS20100352A3 RS20100352A3 (en) 2012-08-31

Family

ID=46025187

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20100352A RS20100352A3 (en) 2010-08-06 2010-08-06 Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

Country Status (1)

Country Link
RS (1) RS20100352A3 (en)

Also Published As

Publication number Publication date
RS20100352A3 (en) 2012-08-31

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RS20100352A2 (en) Method of preparation and use of pharmacologically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone