RS20060382A - Calcitonin gene related peptide receptor antagonists - Google Patents
Calcitonin gene related peptide receptor antagonistsInfo
- Publication number
- RS20060382A RS20060382A YUP-2006/0382A YUP20060382A RS20060382A RS 20060382 A RS20060382 A RS 20060382A YU P20060382 A YUP20060382 A YU P20060382A RS 20060382 A RS20060382 A RS 20060382A
- Authority
- RS
- Serbia
- Prior art keywords
- related peptide
- treatment
- calcitonin gene
- receptor antagonists
- peptide receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Abstract
The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors ('CGRP-receptor'), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2003/038799 WO2005065779A1 (en) | 2003-12-05 | 2003-12-05 | Calcitonin gene related peptide receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
RS20060382A true RS20060382A (en) | 2008-09-29 |
Family
ID=34748456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YUP-2006/0382A RS20060382A (en) | 2003-12-05 | 2003-12-05 | Calcitonin gene related peptide receptor antagonists |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1689493A4 (en) |
JP (1) | JP2007524568A (en) |
CN (1) | CN100558428C (en) |
AR (1) | AR046788A1 (en) |
AU (1) | AU2003297694A1 (en) |
BR (1) | BR0318637A (en) |
CA (1) | CA2549330A1 (en) |
IL (1) | IL176018A0 (en) |
IS (1) | IS8482A (en) |
NO (1) | NO20062648L (en) |
PE (1) | PE20051036A1 (en) |
RS (1) | RS20060382A (en) |
TW (1) | TWI284534B (en) |
UA (1) | UA81563C2 (en) |
WO (1) | WO2005065779A1 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7220862B2 (en) | 2002-06-05 | 2007-05-22 | Bristol-Myers Squibb Company | Calcitonin gene related peptide receptor antagonists |
US7842808B2 (en) | 2002-06-05 | 2010-11-30 | Bristol-Myers Squibb Company | Anti-migraine spirocycles |
US7569578B2 (en) | 2003-12-05 | 2009-08-04 | Bristol-Meyers Squibb Company | Heterocyclic anti-migraine agents |
JP4769082B2 (en) * | 2003-12-17 | 2011-09-07 | 武田薬品工業株式会社 | Urea derivatives, their production and use |
TW200533398A (en) | 2004-03-29 | 2005-10-16 | Bristol Myers Squibb Co | Novel therapeutic agents for the treatment of migraine |
US7786141B2 (en) | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
EP1781288A2 (en) | 2004-08-19 | 2007-05-09 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
US7384931B2 (en) | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
US7384930B2 (en) | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
US7449586B2 (en) | 2004-12-03 | 2008-11-11 | Bristol-Myers Squibb Company | Processes for the preparation of CGRP-receptor antagonists and intermediates thereof |
US7834007B2 (en) | 2005-08-25 | 2010-11-16 | Bristol-Myers Squibb Company | CGRP antagonists |
US8168592B2 (en) | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
DE102005050892A1 (en) * | 2005-10-21 | 2007-04-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Selected CGRP antagonists, process for their preparation and their use as pharmaceuticals |
US7473778B2 (en) | 2005-12-24 | 2009-01-06 | Boehringer Ingelheim International Gmbh | 3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)-one |
RU2008137593A (en) | 2006-02-22 | 2010-03-27 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | MUSCARINE RECEPTOR MODULATORS |
JP5385297B2 (en) | 2007-11-22 | 2014-01-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | New compounds |
CN105012318B (en) * | 2014-04-17 | 2020-02-11 | 沈华浩 | Application of sulfonamide compound in airway chronic inflammatory diseases |
GB201519194D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP receptor antagonists |
GB201519196D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP Receptor Antagonists |
GB201519195D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP Receptor Antagonists |
AR126954A1 (en) * | 2021-09-02 | 2023-12-06 | Biohaven Pharm Holding Co Ltd | METHODS FOR TREATING PSORIASIS WITH ONE OR MORE CGRP RECEPTOR ANTAGONISTS |
CN117624191A (en) * | 2022-08-30 | 2024-03-01 | 熙源安健医药(上海)有限公司 | Indazole carboxamide derivatives, preparation method and application thereof |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11512396A (en) | 1995-09-05 | 1999-10-26 | スミスクライン・ビーチャム・コーポレイション | Compounds and methods |
US5869489A (en) * | 1996-03-25 | 1999-02-09 | Merck & Co., Inc. | Trypthophan ureas as neurokinnin antagonists |
GB2311523A (en) * | 1996-03-25 | 1997-10-01 | Merck & Co Inc | Tryptophan urea tachykinin receptor antagonists |
EP0934068A1 (en) | 1996-09-09 | 1999-08-11 | Smithkline Beecham Corporation | Compounds and methods |
BR9712023A (en) | 1996-09-10 | 1999-08-31 | Thomae Gmbh Dr K | Derived amino acids, drugs containing these compounds and processes for their preparation. |
US6063796A (en) * | 1997-04-04 | 2000-05-16 | Merck & Co., Inc. | Somatostatin agonists |
WO1998056779A1 (en) | 1997-06-13 | 1998-12-17 | Smithkline Beecham Corporation | 4-sulfinyl benzamides as calcitonin gene-related peptide receptor antagonists |
AU5265599A (en) | 1998-04-08 | 1999-11-01 | Takeda Chemical Industries Ltd. | Amine compounds, their production and their use as somatostatin receptor antagonists or agonists |
WO2000018764A1 (en) * | 1998-09-30 | 2000-04-06 | Merck Sharp & Dohme Limited | Benzimidazolinyl piperidines as cgrp ligands |
DE19911039A1 (en) | 1999-03-12 | 2000-09-14 | Boehringer Ingelheim Pharma | Modified amino acid amides, pharmaceutical compositions containing these compounds and process for their preparation |
US6313097B1 (en) | 1999-03-02 | 2001-11-06 | Boehringer Ingelheim Pharma Kg | Antagonists of calcitonin gene-related peptide |
US6521609B1 (en) | 1999-08-10 | 2003-02-18 | Boehringer Ingelheim Pharma Kg | Use of CGRP antagonists and CGRP release inhibitors for combating menopausal hot flushes |
AU7556800A (en) | 1999-10-07 | 2001-05-10 | Tadeka Chemical Industries, Ltd. | Amine derivatives |
DE19952147A1 (en) | 1999-10-29 | 2001-05-03 | Boehringer Ingelheim Pharma | New cyclopropanes, pharmaceutical compositions containing these compounds and process for their preparation |
DE19952146A1 (en) | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkanes, arylalkenes and aryl-azaalkanes, medicaments containing these compounds and process for their preparation |
DE19963868A1 (en) | 1999-12-30 | 2001-07-12 | Boehringer Ingelheim Pharma | New substituted piperidines, pharmaceutical compositions containing these compounds and process for their preparation |
EP1323709A1 (en) * | 2000-09-14 | 2003-07-02 | Toray Industries, Inc. | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient |
US20030181462A1 (en) | 2001-08-17 | 2003-09-25 | Boehringer Ingelheim Pharma Kg | Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine |
WO2003027252A2 (en) | 2001-09-27 | 2003-04-03 | Merck & Co., Inc. | Isolated dna molecules encoding humanized calcitonin gene-related peptide receptor, related non-human transgenic animals and assay methods |
US6900317B2 (en) | 2002-02-19 | 2005-05-31 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Salts of the CGRP antagonist BIBN4096 and inhalable powdered medicaments containing them |
DE10211770A1 (en) | 2002-03-14 | 2003-10-02 | Boehringer Ingelheim Pharma | Novel substituted piperidines, pharmaceutical compositions containing them and processes for their preparation |
JP4490809B2 (en) * | 2002-06-05 | 2010-06-30 | ブリストル−マイヤーズ スクイブ カンパニー | Calcitonin gene-related peptide receptor antagonist |
DE10300973A1 (en) * | 2003-01-14 | 2004-07-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New carboxylic acids and their esters, medicaments containing these compounds and processes for their preparation |
-
2003
- 2003-12-05 BR BRPI0318637-7A patent/BR0318637A/en not_active IP Right Cessation
- 2003-12-05 WO PCT/US2003/038799 patent/WO2005065779A1/en active Application Filing
- 2003-12-05 CA CA002549330A patent/CA2549330A1/en not_active Abandoned
- 2003-12-05 JP JP2005513137A patent/JP2007524568A/en not_active Withdrawn
- 2003-12-05 RS YUP-2006/0382A patent/RS20060382A/en unknown
- 2003-12-05 UA UAA200607510A patent/UA81563C2/en unknown
- 2003-12-05 EP EP03819270A patent/EP1689493A4/en not_active Withdrawn
- 2003-12-05 AU AU2003297694A patent/AU2003297694A1/en not_active Abandoned
- 2003-12-05 CN CNB200380111030XA patent/CN100558428C/en not_active Expired - Fee Related
-
2004
- 2004-12-01 TW TW093137052A patent/TWI284534B/en not_active IP Right Cessation
- 2004-12-03 AR ARP040104530A patent/AR046788A1/en unknown
- 2004-12-06 PE PE2004001196A patent/PE20051036A1/en not_active Application Discontinuation
-
2006
- 2006-05-26 IS IS8482A patent/IS8482A/en unknown
- 2006-05-30 IL IL176018A patent/IL176018A0/en unknown
- 2006-06-08 NO NO20062648A patent/NO20062648L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TWI284534B (en) | 2007-08-01 |
CN100558428C (en) | 2009-11-11 |
AR046788A1 (en) | 2005-12-21 |
EP1689493A4 (en) | 2008-04-23 |
CA2549330A1 (en) | 2005-07-21 |
AU2003297694A1 (en) | 2005-08-12 |
WO2005065779A1 (en) | 2005-07-21 |
CN1917921A (en) | 2007-02-21 |
NO20062648L (en) | 2006-08-02 |
UA81563C2 (en) | 2008-01-10 |
PE20051036A1 (en) | 2005-12-11 |
BR0318637A (en) | 2007-02-13 |
JP2007524568A (en) | 2007-08-30 |
TW200529835A (en) | 2005-09-16 |
IL176018A0 (en) | 2006-10-05 |
IS8482A (en) | 2006-05-26 |
EP1689493A1 (en) | 2006-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200407327A (en) | Calcitonin gene related peptide receptor antagonists | |
WO2005056550A3 (en) | Heterocyclic anti-migraine agents | |
RS20060382A (en) | Calcitonin gene related peptide receptor antagonists | |
TW200628470A (en) | Constrained compounds as CGRP-receptor antagonists | |
BRPI0509341A (en) | heterocyclic cgrp anatagonists for the treatment of migraine | |
TN2012000139A1 (en) | Cgrp receptor antagonists | |
WO2009126530A3 (en) | Piperidine derivatives as cgrp receptor antagonists | |
WO2007130860A3 (en) | Constrained compounds as cgrp-receptor antagonists | |
EP2582432B1 (en) | Ureido-pyrazole derivatives for use in the treatment of rhinovirus infections | |
EP2414347B1 (en) | P38map kinase inhibitor | |
EP2582433B1 (en) | Ureido-pyrazole derivatives for use in the treatment of rhinovirus infections | |
MX352171B (en) | N- (5s, 6s, 9r) - 5 -amino- 6 - (2, 3 - difluorophenyl) -6, 7, 8, 9 - tetrahydro - 5h - cyclohepta [b] pyridin-9 -yl- 4 - (2 - oxo-2, 3 - dihydro - 1h- imidazo [4, 5 -b] pyridin - 1 - yl) piperidine - 1 - carboxylate, hemisulfate salt. | |
EA201200876A1 (en) | NEW ANTAGONISTS CCR2 RECEPTOR AND THEIR APPLICATION | |
RU2007146669A (en) | ADENOSINE RECEPTOR ANTAGONISTS | |
WO2010018109A3 (en) | Substituted aminotetralines | |
EA200970302A1 (en) | TIOPHENPYRAZOLOPIRIMIDIN COMPOUNDS | |
EA201270751A1 (en) | ANTAGONIST RECEPTOR CGRP | |
WO2007130927A3 (en) | Condensed tricyclic compounds as cgrp-receptor antagonists | |
WO2007131020A3 (en) | Constrained compounds as cgrp-receptor antagonists | |
HRP20060236A2 (en) | Calcitonin gene related peptide receptor antagonists | |
TH65848B (en) | Resistor anthracite for calcitonin rylate peptide | |
TH78134A (en) | Resistor anthracite for calcitonin rylate peptide | |
TH87766A (en) | Heterocyclic anti-migraine agents | |
TH87766B (en) | Heterocyclic anti-migraine agents | |
TH75066B (en) | Peptide receptor antagonist associated with the calicitonin gene. |