RO88084B1 - Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia - Google Patents

Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia

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Publication number
RO88084B1
RO88084B1 RO113704A RO11370484A RO88084B1 RO 88084 B1 RO88084 B1 RO 88084B1 RO 113704 A RO113704 A RO 113704A RO 11370484 A RO11370484 A RO 11370484A RO 88084 B1 RO88084 B1 RO 88084B1
Authority
RO
Romania
Prior art keywords
tyramine
marker
cortisole
adjoint
making
Prior art date
Application number
RO113704A
Other languages
English (en)
Inventor
Ion Dorobantu
Original Assignee
Institutul De Fizica Si Inginerie Nucleara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institutul De Fizica Si Inginerie Nucleara filed Critical Institutul De Fizica Si Inginerie Nucleara
Priority to RO113704A priority Critical patent/RO88084B1/ro
Publication of RO88084B1 publication Critical patent/RO88084B1/ro

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  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Conjugatul marker cortisoltiramina are structura chimica din formula generala I: (vezi formula) si se prezinta sub forma de lichid incolor, solubil în alcooli inferiori, cu greutatea moleculara de 711 daltoni si cu activitate specifica de 4 mCi/miug. Procedeul de obtinere a conjugatului marker consta în aceea ca cortisol-6-carboxietiltioeter se trateaza cu tiramina, în mediu de cloroformiat de etil, la temperatura de 4 degree C într-o anumita perioada de timp, dupa care produsul se marcheaza si se purifica dupa metode cunoscute.
RO113704A 1984-02-24 1984-02-24 Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia RO88084B1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RO113704A RO88084B1 (ro) 1984-02-24 1984-02-24 Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RO113704A RO88084B1 (ro) 1984-02-24 1984-02-24 Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia

Publications (1)

Publication Number Publication Date
RO88084B1 true RO88084B1 (ro) 1985-11-01

Family

ID=40904003

Family Applications (1)

Application Number Title Priority Date Filing Date
RO113704A RO88084B1 (ro) 1984-02-24 1984-02-24 Conjugat marker de cortisol-tiramina si procedeu de obtinere al acestuia

Country Status (1)

Country Link
RO (1) RO88084B1 (ro)

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