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Application filed by Institutul De Cercetari Chimico-FarmaceuticefiledCriticalInstitutul De Cercetari Chimico-Farmaceutice
Priority to RO106265ApriorityCriticalpatent/RO84120B1/en
Publication of RO84120A2publicationCriticalpatent/RO84120A2/en
Publication of RO84120B1publicationCriticalpatent/RO84120B1/en
Inventia se refera la un procedeu de obtinere a 1-metil-2-hidroximetil-5-nitroimidazolului din 1-metil-4(5)-nitroimidazol, printr-o reactie de hidroximetilare cu paraformaldehida la temperatura de 140...145 degree C, care foloseste toluenul ca mediu de reactie.The invention relates to a process for the preparation of 1-methyl-2-hydroxymethyl-5-nitroimidazole from 1-methyl-4 (S) -nitroimidazole by a hydroxymethylation reaction with paraformaldehyde at a temperature of 140 ... 145 ° C , which uses toluene as the reaction medium.
RO106265A1982-01-081982-01-08Process for preparing 1-methyl-2-hydroxymethyl-5-nitroimidazole
RO84120B1
(en)