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Application filed by Victor Patrascu Ionel, Muntean Ion, Ciobanu MariafiledCriticalVictor Patrascu Ionel
Priority to RO107999ApriorityCriticalpatent/RO82518B1/en
Publication of RO82518B1publicationCriticalpatent/RO82518B1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Abstract
Procedeu de obtinere a vaccinului contra bolii Carre, prin recoltarea mediului de cultura si a celulelor infectate cu acest virus cînd în fenomenul citopatic a atins 70...80% din monostrat, centrifugarea si conservarea la -100...-196 degree C pîna la liofilizare în diluant protector SPGA sau peptona-lactoza, care consta în faptul ca virusul folosit este tulpina Canine Distemper Virus-MC clona 31, înregistrata în colectia Centrului de cercetari si biopreparate pentru pasari si animale mici - Voluntari sun nr. 31.Procedure for obtaining the vaccine against Carre disease by harvesting the culture medium and cells infected with this virus when in the cytopathic phenomenon reached 70 ... 80% of the monolayer, centrifuging and preserving at -100 ... 196 degrees Celsius to lyophilization in SPGA protector diluent or peptone-lactose, which consists in the fact that the virus used is the Canine Distemper Virus-MC clone 31 strain, registered in the collection of the Center for Research and Biopreparations for Birds and Small Animals - volunteers call no. 31.
RO107999A1982-06-281982-06-28Process for obtaining the vaccine against carre disease
RO82518B1
(en)
Feline virus vaccines obtained by propagation and serial passage attenuation of virulent feline viruses in diploid feline embryo tissue cell serial passage subculture strains