RO134192A3 - Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect - Google Patents

Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect

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Publication number
RO134192A3
RO134192A3 ROA201900163A RO201900163A RO134192A3 RO 134192 A3 RO134192 A3 RO 134192A3 RO A201900163 A ROA201900163 A RO A201900163A RO 201900163 A RO201900163 A RO 201900163A RO 134192 A3 RO134192 A3 RO 134192A3
Authority
RO
Romania
Prior art keywords
anthracene
obtaining
imidazole
anthracenyl
methylene
Prior art date
Application number
ROA201900163A
Other languages
Romanian (ro)
Other versions
RO134192A0 (en
Inventor
Ionel Mangalagiu
Dorina Amariucăi-Mantu
Vasilichia Antoci
Gheorghiţă Zbancioc
Costel Moldoveanu
Dumitrela Cucu
Ramona Danac
Violeta Mangalagiu
Original Assignee
Universitatea "Alexandru Ioan Cuza" Din Iaşi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitatea "Alexandru Ioan Cuza" Din Iaşi filed Critical Universitatea "Alexandru Ioan Cuza" Din Iaşi
Priority to ROA201900163A priority Critical patent/RO134192A3/en
Publication of RO134192A0 publication Critical patent/RO134192A0/en
Publication of RO134192A3 publication Critical patent/RO134192A3/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a process for obtaining a class of anthracene-imidazole compounds with anti-tuberculosis effect. According to the invention, the process consists in the N-alkylation of the nitrogen N1 from the imidazole, and benzimidazole, respectively, with 9-chloromethyl-anthracene, to result in the intermediates 1-(anthracenyl-9-methylene)-1H-imidazole and 1-(anthracenyl-9-methylene)-1H-benzimidazole, followed by the reaction of quaternization with Z-substituted Ω-bromo-acetophenones of the imidazole/benzimidazole nitrogen N3, to result in the 1-(anthracenyl-9-methylene)-3-(2-(4-Z-phenyl)-2-oxoethyl)-1H-imidazol-3-ium bromide and the 1-(anthracenyl-9-methylene)-3-(2-(4-Z-phenyl)-2-oxoethyl)-1H-benzimidazol-3-ium bromide, respectively.
ROA201900163A 2019-03-13 2019-03-13 Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect RO134192A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ROA201900163A RO134192A3 (en) 2019-03-13 2019-03-13 Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ROA201900163A RO134192A3 (en) 2019-03-13 2019-03-13 Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect

Publications (2)

Publication Number Publication Date
RO134192A0 RO134192A0 (en) 2020-06-30
RO134192A3 true RO134192A3 (en) 2021-03-30

Family

ID=71112318

Family Applications (1)

Application Number Title Priority Date Filing Date
ROA201900163A RO134192A3 (en) 2019-03-13 2019-03-13 Process for obtaining a new class of anthracene-imidazole compounds with anti-tuberculosis effect

Country Status (1)

Country Link
RO (1) RO134192A3 (en)

Also Published As

Publication number Publication date
RO134192A0 (en) 2020-06-30

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