PT88976A - PROCESS FOR THE PREPARATION OF SUBSTITUTED THYOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

PROCESS FOR THE PREPARATION OF SUBSTITUTED THYOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
PT88976A
PT88976A PT88976A PT8897688A PT88976A PT 88976 A PT88976 A PT 88976A PT 88976 A PT88976 A PT 88976A PT 8897688 A PT8897688 A PT 8897688A PT 88976 A PT88976 A PT 88976A
Authority
PT
Portugal
Prior art keywords
substituted
preparation
derivatives
thyoimidazole
pharmaceutical compositions
Prior art date
Application number
PT88976A
Other languages
Portuguese (pt)
Other versions
PT88976B (en
Inventor
Hans-Jochem Lang
Klaus Weidmann
Karl Heinz Scheunemann
Hildegard Nimmesgern
Robert Rippel
Andreas W Herling
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT88976A publication Critical patent/PT88976A/en
Publication of PT88976B publication Critical patent/PT88976B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Abstract

Substituted thienoimidzaole derivatives, processes for their preparation, pharmaceutical preparations containing them and their use as inhibitors of gastric acid secretion. The invention relates to substituted thienoimidazole derivatives of the formula <IMAGE> (I) in which A stands for <IMAGE> T denotes -S-, -SO- or -SO2-, R7 denotes a substituted aryloxy or aralkoxy radical and R1, R2, R3, R4, R5, R6 and R8 have the meanings indicated in the description, processes for their preparation, pharmaceutical preparations containing them and their use as medicaments.
PT88976A 1987-11-13 1988-11-10 PROCESS FOR THE PREPARATION OF SUBSTITUTED THYOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PT88976B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3738520 1987-11-13
DE3819084 1988-06-04
DE3828158 1988-08-19

Publications (2)

Publication Number Publication Date
PT88976A true PT88976A (en) 1988-12-01
PT88976B PT88976B (en) 1993-01-29

Family

ID=27196772

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88976A PT88976B (en) 1987-11-13 1988-11-10 PROCESS FOR THE PREPARATION OF SUBSTITUTED THYOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (20)

Country Link
US (1) US5114955A (en)
EP (1) EP0321385B1 (en)
JP (1) JPH01160984A (en)
KR (1) KR890008146A (en)
CN (1) CN1029314C (en)
AT (1) ATE110078T1 (en)
AU (1) AU607279B2 (en)
DE (1) DE3851133D1 (en)
DK (1) DK166415B1 (en)
ES (1) ES2060672T3 (en)
FI (1) FI90426C (en)
HU (1) HU202238B (en)
IE (1) IE64073B1 (en)
IL (1) IL88349A (en)
MA (1) MA21434A1 (en)
NO (1) NO167981C (en)
NZ (1) NZ226928A (en)
PH (1) PH26365A (en)
PT (1) PT88976B (en)
TN (1) TNSN88123A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
CA2493618A1 (en) * 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (en) * 1968-10-21 1971-06-03
GB8417171D0 (en) * 1984-07-05 1984-08-08 Beecham Group Plc Compounds
FI861772A (en) * 1985-05-07 1986-11-08 Chemie Linz Ag THEN THEN (2,3-D) IMIDED INSULATED FOR THE FRAME FRAMEWORK.
DE3777855D1 (en) * 1986-02-20 1992-05-07 Hoechst Ag SUBSTITUTED THIENOIMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME AND THEIR USE AS AN INGESTIC ACID INHIBITOR.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
AU622866B2 (en) * 1987-07-21 1992-04-30 Hoechst Aktiengesellschaft Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors

Also Published As

Publication number Publication date
EP0321385A3 (en) 1990-06-06
CN1029314C (en) 1995-07-12
NO885040D0 (en) 1988-11-11
PH26365A (en) 1992-06-01
IL88349A (en) 1993-03-15
ES2060672T3 (en) 1994-12-01
DK166415B1 (en) 1993-05-17
IL88349A0 (en) 1989-06-30
EP0321385B1 (en) 1994-08-17
AU607279B2 (en) 1991-02-28
KR890008146A (en) 1989-07-10
TNSN88123A1 (en) 1990-07-10
US5114955A (en) 1992-05-19
HUT50828A (en) 1990-03-28
DE3851133D1 (en) 1994-09-22
PT88976B (en) 1993-01-29
NO167981B (en) 1991-09-23
DK631188A (en) 1989-05-14
FI885172A0 (en) 1988-11-10
HU202238B (en) 1991-02-28
JPH01160984A (en) 1989-06-23
NO167981C (en) 1992-01-02
ATE110078T1 (en) 1994-09-15
MA21434A1 (en) 1989-07-01
EP0321385A2 (en) 1989-06-21
IE64073B1 (en) 1995-07-12
FI90426B (en) 1993-10-29
CN1033052A (en) 1989-05-24
DK631188D0 (en) 1988-11-11
AU2503488A (en) 1989-05-18
NO885040L (en) 1989-05-16
FI885172A (en) 1989-05-14
NZ226928A (en) 1991-08-27
FI90426C (en) 1994-02-10
IE883392L (en) 1989-05-13

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920730

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980131