PT88348A - Processo para a marcacao de substancias com isotopos de tecnecio ou de renio - Google Patents

Processo para a marcacao de substancias com isotopos de tecnecio ou de renio

Info

Publication number
PT88348A
PT88348A PT88348A PT8834888A PT88348A PT 88348 A PT88348 A PT 88348A PT 88348 A PT88348 A PT 88348A PT 8834888 A PT8834888 A PT 8834888A PT 88348 A PT88348 A PT 88348A
Authority
PT
Portugal
Prior art keywords
substances
isotopes
renewable
marking
technical
Prior art date
Application number
PT88348A
Other languages
English (en)
Other versions
PT88348B (pt
Inventor
Michael Magerstadt
Ludwig Kuhlmann
Alexander Schwarz
Axel Steinstrasser
Karl-Heinz Bremer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT88348A publication Critical patent/PT88348A/pt
Publication of PT88348B publication Critical patent/PT88348B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
PT88348A 1987-08-27 1988-08-26 Processo para a marcacao de substancias com isotopos de tecnecio ou de renio PT88348B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873728600 DE3728600A1 (de) 1987-08-27 1987-08-27 Verfahren zur markierung von substanzen mit technetium oder rhenium

Publications (2)

Publication Number Publication Date
PT88348A true PT88348A (pt) 1989-06-30
PT88348B PT88348B (pt) 1995-03-31

Family

ID=6334611

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88348A PT88348B (pt) 1987-08-27 1988-08-26 Processo para a marcacao de substancias com isotopos de tecnecio ou de renio

Country Status (10)

Country Link
US (1) US5219555A (pt)
EP (1) EP0304780B1 (pt)
JP (1) JPS6471826A (pt)
AT (1) ATE65918T1 (pt)
DE (2) DE3728600A1 (pt)
DK (1) DK479788A (pt)
ES (1) ES2024601B3 (pt)
GR (1) GR3002968T3 (pt)
IE (1) IE60872B1 (pt)
PT (1) PT88348B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422096A (en) * 1985-05-08 1995-06-06 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic NMR imaging
US5250285A (en) * 1985-05-08 1993-10-05 The General Hospital Corporation Hydroxy-aryl metal chelates for diagnostic NMR imaging
DE3728600A1 (de) * 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
US5082967A (en) * 1988-06-16 1992-01-21 Washington University Novel fatty acid analog enzyme substrates
DE3911816A1 (de) * 1989-04-11 1990-10-25 Hoechst Ag Substituierte 1,4,7,10-tetraazacyclotridecane, verfahren zu deren herstellung sowie verwendung derselben zur markierung von substanzen mit radionukliden
ATE173336T1 (de) * 1989-08-28 1998-11-15 Gen Hospital Corp Hydroxy-aryl metallchelate für bildformung zur nmr diagnose
ATE147637T1 (de) * 1991-02-05 1997-02-15 Cis Bio Int Verfahren zur herstellung einer mit technetium- 99m markierten organspezifischen substanz
FI923350A (fi) * 1991-07-26 1993-01-27 Hoechst Ag Foerfarande foer maerkning av substanser med teknetium eller renium
US5338864A (en) * 1992-07-06 1994-08-16 Mallinckrodt Medical, Inc. Hexadentate ligands useful in radiographic imaging agents
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5582814A (en) * 1994-04-15 1996-12-10 Metasyn, Inc. 1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
TW319763B (pt) 1995-02-01 1997-11-11 Epix Medical Inc
FR2830253B1 (fr) * 2001-09-28 2005-02-04 Air Liquide Nouveau procede de preparation de macrocycles azotes c-fonctionnalises et nouveaux intermediaires obtenus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
GB8426845D0 (en) * 1984-10-24 1984-11-28 Amersham Int Plc Complexes of technetium-99m
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
GB8603537D0 (en) * 1986-02-13 1986-03-19 Parker D Conjugate compound
DE3728600A1 (de) * 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium

Also Published As

Publication number Publication date
IE882607L (en) 1989-02-27
PT88348B (pt) 1995-03-31
EP0304780B1 (de) 1991-08-07
DE3728600A1 (de) 1989-03-09
GR3002968T3 (en) 1993-01-25
IE60872B1 (en) 1994-08-24
US5219555A (en) 1993-06-15
DE3864103D1 (de) 1991-09-12
DK479788A (da) 1989-02-28
ES2024601B3 (es) 1992-03-01
EP0304780A1 (de) 1989-03-01
JPS6471826A (en) 1989-03-16
ATE65918T1 (de) 1991-08-15
DK479788D0 (da) 1988-08-26

Similar Documents

Publication Publication Date Title
PT88348A (pt) Processo para a marcacao de substancias com isotopos de tecnecio ou de renio
EP0350846A3 (en) Condensed heterocyclic compounds and their use in therapy
ATE16591T1 (de) Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin11-n-alkyl-norscopinether und verfahren zu deren herstellung.
ATE124405T1 (de) 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel.
TR199900537T2 (xx) D�n��t�r�lm�� amino asitler, bunlar� i�eren farmas�tik preparatlar.
DE69006290D1 (de) N-Substituierte Benzyloxyiminderivate, Verfahren zu deren Herstellung und deren Verwendung.
PT97773A (pt) Processo para a preparacao de oxazolidinonas e de composicoes farmaceuticas que as contem
ATE9472T1 (de) Amino-desoxy-1.4; 3.6-dianhydro-hexit-nitrate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
ATA56790A (de) Thieno-triazolo-diazepinderivate, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
ATE489T1 (de) Sila-substituierte 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung, arzneimittel und verfahren zu deren herstellung.
ATA95690A (de) Thieno-triazolo-diazepinderivate, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
PT83356B (pt) Processo para a preparacao de antibioticos macrociclicos
DE3874820D1 (de) Apparat zum herstellen von verschlossenen post- oder briefsendungen.
DE3767894D1 (de) 1,2-dithiol-3-thion-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellung.
DE3583780D1 (de) 2,3-dihydro-1h-inden-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES2038740T3 (es) Procedimiento de obtencion de compuesos guanidicos que comprenden un ion tetrafenilborato sustituido.
ATA86690A (de) 2-substituierte n,n'-ditrimethoxybenzoylpiperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
ATE2423T1 (de) 1-acyloxyphenyl-1,2-diphenylalken-derivate, verfahren zu deren herstellung und eine diese derivate enthaltende pharmazeutische zusammensetzung.
DE3687870D1 (de) 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung.
EP0221493A3 (en) Use of gyrase blocking agents in decontaminating cell cultures infested by mycoplasmas
ATE59035T1 (de) Basisch substituierte benzofurancarbonsaeureamide, verfahren zu ihrer herstellung und sie enthaltende therapeutische mittel.
ATE111894T1 (de) Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate.
ATA259590A (de) 3-(n-methyl-n-alkyl)-amino-2-methoxymethylenpro an-1-ol-derivate, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
DE69104286D1 (de) Disubstituierte Polymethylenimine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel.
ATA234589A (de) Neue 2-methoxycarbonyl substituierte n,n'-di(trimethoxybenzoyl)piperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940909

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19970331