PT83788A - Fermentation method for hepatitis vaccine production - Google Patents

Fermentation method for hepatitis vaccine production

Info

Publication number
PT83788A
PT83788A PT8378886A PT8378886A PT83788A PT 83788 A PT83788 A PT 83788A PT 8378886 A PT8378886 A PT 8378886A PT 8378886 A PT8378886 A PT 8378886A PT 83788 A PT83788 A PT 83788A
Authority
PT
Portugal
Prior art keywords
concn
pref
medium
fermentation method
vaccine production
Prior art date
Application number
PT8378886A
Other languages
Portuguese (pt)
Other versions
PT83788B (en
Inventor
John C Fieschko
Original Assignee
Amgen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen filed Critical Amgen
Priority to PT8378886A priority Critical patent/PT83788B/en
Publication of PT83788A publication Critical patent/PT83788A/en
Publication of PT83788B publication Critical patent/PT83788B/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Culture medium for growing a yeast capable of expressing a foreign gene prod. comprises balanced free amino acids at 20-160 g/l. The balanced free amino acids are pref. used at 110 g.l, and suitably casamino acids are used. The C source concn. in the medium is pref. kept above but as close to zero as possible. The medium is pref. satd. with O2 to at least 30% air saturation. The cultivation is oref. effected at about 25 Deg.C. With a low gluclose concn. and high O2 concn. formation of EtOH is minimised. Suitable Saccharomyces cerevisiae is used.
PT8378886A 1986-11-21 1986-11-21 FERMENTATION PROCESS FOR THE PREPARATION OF A HEPATITIS VACCINE PT83788B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PT8378886A PT83788B (en) 1986-11-21 1986-11-21 FERMENTATION PROCESS FOR THE PREPARATION OF A HEPATITIS VACCINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT8378886A PT83788B (en) 1986-11-21 1986-11-21 FERMENTATION PROCESS FOR THE PREPARATION OF A HEPATITIS VACCINE

Publications (2)

Publication Number Publication Date
PT83788A true PT83788A (en) 1986-12-01
PT83788B PT83788B (en) 1989-05-12

Family

ID=20083947

Family Applications (1)

Application Number Title Priority Date Filing Date
PT8378886A PT83788B (en) 1986-11-21 1986-11-21 FERMENTATION PROCESS FOR THE PREPARATION OF A HEPATITIS VACCINE

Country Status (1)

Country Link
PT (1) PT83788B (en)

Also Published As

Publication number Publication date
PT83788B (en) 1989-05-12

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