PT83267A - Novel beta-lactama compounds - Google Patents

Novel beta-lactama compounds

Info

Publication number
PT83267A
PT83267A PT83267A PT8326786A PT83267A PT 83267 A PT83267 A PT 83267A PT 83267 A PT83267 A PT 83267A PT 8326786 A PT8326786 A PT 8326786A PT 83267 A PT83267 A PT 83267A
Authority
PT
Portugal
Prior art keywords
compounds
lactama
novel beta
salts
compound
Prior art date
Application number
PT83267A
Other languages
Portuguese (pt)
Other versions
PT83267B (en
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT83267A publication Critical patent/PT83267A/en
Publication of PT83267B publication Critical patent/PT83267B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
    • G02B1/14—Protective coatings, e.g. hard coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Abstract

A compound having the formula (I):is described, together with salts thereof and an enzymatic process for converting such compounds into clavulanic acid.A process for the preparation of the compound of formula (I) and its salts is disclosed, together with intermediates for use therein.
PT83267A 1985-08-29 1986-08-27 PROCESS OF PREPARATION OF COMPOUNDS BETA-LACTAMA, OF THEIR INTERMEDIARIES AND OF CLAVULANIC ACID PT83267B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858521516A GB8521516D0 (en) 1985-08-29 1985-08-29 Compounds

Publications (2)

Publication Number Publication Date
PT83267A true PT83267A (en) 1986-09-01
PT83267B PT83267B (en) 1988-08-17

Family

ID=10584437

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83267A PT83267B (en) 1985-08-29 1986-08-27 PROCESS OF PREPARATION OF COMPOUNDS BETA-LACTAMA, OF THEIR INTERMEDIARIES AND OF CLAVULANIC ACID

Country Status (11)

Country Link
US (2) US4795809A (en)
EP (1) EP0213914B1 (en)
JP (4) JP2530825B2 (en)
AT (1) ATE82291T1 (en)
CA (1) CA1338143C (en)
DE (1) DE3687100T2 (en)
ES (1) ES2001410A6 (en)
GB (1) GB8521516D0 (en)
GR (1) GR862214B (en)
HK (1) HK26596A (en)
PT (1) PT83267B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813055D0 (en) * 1988-06-02 1988-07-06 Beecham Group Plc Novel substance
JP3730263B2 (en) * 1992-05-27 2005-12-21 ケーエルエー・インストルメンツ・コーポレーション Apparatus and method for automatic substrate inspection using charged particle beam
DE69324163T2 (en) * 1992-12-02 1999-09-23 Smithkline Beecham Plc METHOD FOR PRODUCING CLAVULANIC ACID
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
SI9500074A (en) * 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
GB9515809D0 (en) * 1995-08-02 1995-10-04 Smithkline Beecham Plc Process
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862008A (en) * 1973-12-03 1975-01-21 Lilly Co Eli Process for deacetoxycephalosporin c.
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
GB1563103A (en) * 1975-10-13 1980-03-19 Beecham Group Ltd Process for the preparation of clavulanic acid
US4078067A (en) * 1976-04-12 1978-03-07 Merck & Co., Inc. 3-(.beta.-Aminoethylidene)-7-oxo-4-oxaazabicyclo[3.2.0]heptane-2-carboxylic acid and derivatives thereof
GB1585124A (en) * 1976-06-04 1981-02-25 Glaxo Lab Ltd Clavulanic acid derivatives
AT363181B (en) * 1976-10-25 1981-07-10 Glaxo Lab Ltd METHOD FOR PRODUCING NEW CLAVULANIC ACID DERIVATIVES
GB1603208A (en) * 1977-04-27 1981-11-18 Beecham Group Ltd Aminodeoxyclavulanic acid and acyl derivatives threreof
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
JPS5835677B2 (en) * 1982-08-05 1983-08-04 武田薬品工業株式会社 New bacterial species Streptomyces cutulahamanus

Also Published As

Publication number Publication date
DE3687100D1 (en) 1992-12-17
JPH08259530A (en) 1996-10-08
JP2648472B2 (en) 1997-08-27
US4795809A (en) 1989-01-03
JP2530825B2 (en) 1996-09-04
EP0213914A3 (en) 1988-07-27
JPS6259281A (en) 1987-03-14
ES2001410A6 (en) 1988-05-16
JP2604571B2 (en) 1997-04-30
DE3687100T2 (en) 1993-04-15
EP0213914B1 (en) 1992-11-11
JPH08242874A (en) 1996-09-24
GR862214B (en) 1986-12-31
JPH08266274A (en) 1996-10-15
US5130241A (en) 1992-07-14
JP2698062B2 (en) 1998-01-19
CA1338143C (en) 1996-03-12
EP0213914A2 (en) 1987-03-11
GB8521516D0 (en) 1985-10-02
ATE82291T1 (en) 1992-11-15
PT83267B (en) 1988-08-17
HK26596A (en) 1996-02-16

Similar Documents

Publication Publication Date Title
ES8800245A1 (en) and processes for producing the compounds.
ES2000603A6 (en) Process for the preparation of aryl-piperidine carbinols.
ES8801920A1 (en) Process for the preparation of 1,8-bridged 4-quinolone-3-carboxylic acids.
NO860424L (en) PROCEDURE FOR THE PREPARATION OF 6-THIOXANTHIN DERIVATIVES.
AU8293387A (en) Quinoline compound
HUT40638A (en) Process for producing 1,2-dithiolane-3-pentanoic acid
PT83267A (en) Novel beta-lactama compounds
MY101618A (en) Intermediates for the production of epipodophyloxin and related compounds and processes for the preparation and use thereof
ES8802485A1 (en) Aminoacrylic acid derivatives.
UA19160A (en) A process for preparation of alkyl anilinofumarate
ES8405404A1 (en) Process for the preparation of bicycloheptane derivatives, and novel bicycloheptane derivatives.
ES8707530A1 (en) Octahydroindolizine compounds useful as analgesics.
ES2000405A6 (en) Process for preparing cotarnine.
AU575964B2 (en) Pineapple ketone carbonate derivatives
FR2505832B1 (en)
ES8704447A1 (en) Stereoselective process and chiral intermediates for aryloxydropanolamines.
ES8606271A1 (en) Taurine derivatives
GB8519264D0 (en) Chemical compounds
SU1167881A1 (en) Fenylhydrazide of morpholinediethylacetic acid
ES2000283A6 (en) Cycloaliphatic ketoamines.
SU1269465A1 (en) Method of obtaining 2-aniline-7-hydroxi-6h-1,3,4-thiadziazipyne of common formula
ES2194871T3 (en) DEHYDROGENASE OF CLAVULANIC ACID, PREPARATION AND USE FOR THE PRODUCTION OF CLAVULANIC ACID.
CA1231973A (en) META- AND PARA-ISOPROPENYL-.alpha.,.alpha.- DIMETHYLBENZYLAMINE

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990831