PT83095B - Method for the stabilization of growth promoting hormones using polyoxyethylene-polyoxypropylene copolymers - Google Patents

Method for the stabilization of growth promoting hormones using polyoxyethylene-polyoxypropylene copolymers

Info

Publication number
PT83095B
PT83095B PT83095A PT8309586A PT83095B PT 83095 B PT83095 B PT 83095B PT 83095 A PT83095 A PT 83095A PT 8309586 A PT8309586 A PT 8309586A PT 83095 B PT83095 B PT 83095B
Authority
PT
Portugal
Prior art keywords
polyoxyethylene
stabilization
growth promoting
polyoxypropylene copolymers
promoting hormones
Prior art date
Application number
PT83095A
Other languages
English (en)
Other versions
PT83095A (en
Inventor
Aleksander Blum
Kallidaikuri Silvaramakrishnan
Raji Viswanathan
Original Assignee
Int Minerals & Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Minerals & Chem Corp filed Critical Int Minerals & Chem Corp
Publication of PT83095A publication Critical patent/PT83095A/pt
Publication of PT83095B publication Critical patent/PT83095B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT83095A 1985-07-30 1986-07-29 Method for the stabilization of growth promoting hormones using polyoxyethylene-polyoxypropylene copolymers PT83095B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76063085A 1985-07-30 1985-07-30

Publications (2)

Publication Number Publication Date
PT83095A PT83095A (en) 1986-08-01
PT83095B true PT83095B (en) 1987-12-23

Family

ID=25059690

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83095A PT83095B (en) 1985-07-30 1986-07-29 Method for the stabilization of growth promoting hormones using polyoxyethylene-polyoxypropylene copolymers

Country Status (10)

Country Link
EP (1) EP0211601A3 (pt)
JP (1) JPS6270319A (pt)
KR (1) KR870000934A (pt)
CN (1) CN86105483A (pt)
AU (1) AU6073386A (pt)
BR (1) BR8603586A (pt)
DK (1) DK363086A (pt)
IL (1) IL79552A0 (pt)
PT (1) PT83095B (pt)
ZA (1) ZA865704B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857505A (en) * 1987-03-09 1989-08-15 American Cyanamid Company Sustained release compositions for parenteral administration and their use
GB8725427D0 (en) * 1987-10-30 1987-12-02 Lilly Industries Ltd Somatotropin formulations
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
US5981485A (en) * 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
US5763394A (en) * 1988-04-15 1998-06-09 Genentech, Inc. Human growth hormone aqueous formulation
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
DE69334134T2 (de) * 1992-07-31 2007-12-20 Genentech, Inc., South San Francisco Wässrige Formulierung enthaltend Menschliches Wachstumshormon
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US6277410B1 (en) 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
ZA949350B (en) 1994-01-25 1996-05-24 Upjohn Co Aqueous prolonged release formulation
US6353055B1 (en) 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
AUPN801296A0 (en) 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
NZ516507A (en) * 1999-07-12 2004-02-27 Grandis Biotech Gmbh Growth hormone formulations that are resistant to crystallisation
ES2282134T3 (es) * 1999-09-11 2007-10-16 THE PROCTER & GAMBLE COMPANY Copolimeros de polioxialquileno que contienen vehiculos liquidos fluidos.
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
US7256180B2 (en) 2000-04-28 2007-08-14 Supratek Pharma Inc. Compositions and methods for inducing activation of dendritic cells
GB2371227A (en) * 2001-01-10 2002-07-24 Grandis Biotech Gmbh Crystallisation - resistant aqueous growth hormone formulations
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
EP1603588A2 (en) * 2003-03-18 2005-12-14 Ares Trading S.A. Stabilisation of growth hormones in solution
EP1740213B9 (en) * 2004-04-07 2012-06-13 Ares Trading S.A. Liquid growth hormone formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1224148A (en) * 1983-05-16 1987-07-14 John L. Haslam Drug delivery system utilizing thermosetting gels
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
CA1244347A (en) * 1984-05-29 1988-11-08 Eddie H. Massey Stabilized insulin formulations

Also Published As

Publication number Publication date
CN86105483A (zh) 1987-01-28
DK363086A (da) 1987-01-31
IL79552A0 (en) 1986-10-31
ZA865704B (en) 1987-06-24
DK363086D0 (da) 1986-07-30
PT83095A (en) 1986-08-01
JPS6270319A (ja) 1987-03-31
KR870000934A (ko) 1987-03-10
AU6073386A (en) 1987-02-05
EP0211601A2 (en) 1987-02-25
BR8603586A (pt) 1987-03-10
EP0211601A3 (en) 1988-01-13

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