PT78939B - Process for preparing esters of pantetheine and pantethine with 3-pyridineacetic or 3-(3-pyridylmethoxycarbonyl)-propionic acid and of pharmaceutical compositions containing the same - Google Patents

Process for preparing esters of pantetheine and pantethine with 3-pyridineacetic or 3-(3-pyridylmethoxycarbonyl)-propionic acid and of pharmaceutical compositions containing the same

Info

Publication number
PT78939B
PT78939B PT78939A PT7893984A PT78939B PT 78939 B PT78939 B PT 78939B PT 78939 A PT78939 A PT 78939A PT 7893984 A PT7893984 A PT 7893984A PT 78939 B PT78939 B PT 78939B
Authority
PT
Portugal
Prior art keywords
pyridineacetic
pyridylmethoxycarbonyl
pantetheine
pantethine
pharmaceutical compositions
Prior art date
Application number
PT78939A
Other languages
English (en)
Other versions
PT78939A (en
Inventor
Giampaolo Picciola
Piergiorgio Gentili
Franco Ravenna
Mario Riva
Original Assignee
Maggioni Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838319457A external-priority patent/GB8319457D0/en
Priority claimed from GB838333302A external-priority patent/GB8333302D0/en
Application filed by Maggioni Farma filed Critical Maggioni Farma
Publication of PT78939A publication Critical patent/PT78939A/pt
Publication of PT78939B publication Critical patent/PT78939B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/59—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with at least one of the bonds being to sulfur

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78939A 1983-07-19 1984-07-18 Process for preparing esters of pantetheine and pantethine with 3-pyridineacetic or 3-(3-pyridylmethoxycarbonyl)-propionic acid and of pharmaceutical compositions containing the same PT78939B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838319457A GB8319457D0 (en) 1983-07-19 1983-07-19 Compounds with hypolipemic activity
GB838333302A GB8333302D0 (en) 1983-12-14 1983-12-14 Compounds

Publications (2)

Publication Number Publication Date
PT78939A PT78939A (en) 1984-08-01
PT78939B true PT78939B (en) 1986-10-23

Family

ID=26286642

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78939A PT78939B (en) 1983-07-19 1984-07-18 Process for preparing esters of pantetheine and pantethine with 3-pyridineacetic or 3-(3-pyridylmethoxycarbonyl)-propionic acid and of pharmaceutical compositions containing the same

Country Status (10)

Country Link
US (1) US4571401A (pt)
EP (1) EP0131995B1 (pt)
AU (1) AU562162B2 (pt)
CA (1) CA1254214A (pt)
DE (1) DE3469170D1 (pt)
ES (1) ES8506611A1 (pt)
GR (1) GR81553B (pt)
HU (1) HU200163B (pt)
IT (1) IT1214473B (pt)
PT (1) PT78939B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965621A (en) * 1995-08-17 1999-10-12 Allergan Methods and compositions for reducing or maintaining body weight in a mammal
GB9525828D0 (en) * 1995-12-18 1996-02-21 Bayer Ag Use of hetarylacetic acid derivatives
US20070105793A1 (en) * 2005-11-04 2007-05-10 Curt Hendrix Compositions and methods using nicotinic acid for treatment of hypercholesterolemia, hyperlipidemia nd cardiovascular disease
WO2014083476A2 (en) * 2012-11-27 2014-06-05 Mahesh Kandula Compositions and methods for the treatment of metabolic and lipid disorders
WO2014087307A2 (en) * 2012-12-04 2014-06-12 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome and diabetes
WO2014087323A2 (en) * 2012-12-06 2014-06-12 Mahesh Kandula Compositions and methods for the treatment of autoimmune and chronic metabolic diseases
WO2014106804A2 (en) * 2013-01-04 2014-07-10 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome and diabetes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620544A1 (de) * 1965-04-23 1970-04-30 Takeda Chemical Industries Ltd Neue Pantothensaeurederivate und Verfahren zu ihrer Herstellung
US4288441A (en) * 1980-07-30 1981-09-08 Daiichi Seiyaku Co., Ltd. Nicotinoyl pantetheine derivatives

Also Published As

Publication number Publication date
GR81553B (pt) 1984-12-11
US4571401A (en) 1986-02-18
EP0131995B1 (en) 1988-02-03
DE3469170D1 (en) 1988-03-10
EP0131995A1 (en) 1985-01-23
ES534463A0 (es) 1985-06-01
IT1214473B (it) 1990-01-18
IT8421933A0 (it) 1984-07-18
AU3040484A (en) 1985-01-24
ES8506611A1 (es) 1985-06-01
AU562162B2 (en) 1987-05-28
HUT34726A (en) 1985-04-28
HU200163B (en) 1990-04-28
PT78939A (en) 1984-08-01
CA1254214A (en) 1989-05-16

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