PT78228B - Process for preparing 6-(hydroxyalkyl)-2-(heteroarylalkylthio)--penems and pharmaceutical compositions containing them - Google Patents
Process for preparing 6-(hydroxyalkyl)-2-(heteroarylalkylthio)--penems and pharmaceutical compositions containing themInfo
- Publication number
- PT78228B PT78228B PT78228A PT7822884A PT78228B PT 78228 B PT78228 B PT 78228B PT 78228 A PT78228 A PT 78228A PT 7822884 A PT7822884 A PT 7822884A PT 78228 B PT78228 B PT 78228B
- Authority
- PT
- Portugal
- Prior art keywords
- heteroarylalkylthio
- penems
- hydroxyalkyl
- preparing
- pharmaceutical compositions
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47528183A | 1983-03-14 | 1983-03-14 | |
| US56458683A | 1983-12-22 | 1983-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT78228A PT78228A (en) | 1984-04-01 |
| PT78228B true PT78228B (en) | 1986-08-12 |
Family
ID=27044731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78228A PT78228B (en) | 1983-03-14 | 1984-03-09 | Process for preparing 6-(hydroxyalkyl)-2-(heteroarylalkylthio)--penems and pharmaceutical compositions containing them |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0118875B1 (enEXAMPLES) |
| AU (1) | AU578238B2 (enEXAMPLES) |
| CA (1) | CA1254553A (enEXAMPLES) |
| DE (1) | DE3468107D1 (enEXAMPLES) |
| DK (1) | DK141784A (enEXAMPLES) |
| GR (1) | GR79833B (enEXAMPLES) |
| HU (1) | HU194247B (enEXAMPLES) |
| IL (1) | IL71212A (enEXAMPLES) |
| NZ (1) | NZ207451A (enEXAMPLES) |
| PH (1) | PH20539A (enEXAMPLES) |
| PT (1) | PT78228B (enEXAMPLES) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4614738A (en) * | 1983-03-25 | 1986-09-30 | Schering Corporation | 2-(N-heterocycloaliphaticthio)penems |
| US4587241A (en) * | 1983-11-28 | 1986-05-06 | Schering Corporation | Heterocyclic substituted penems |
| GB8509181D0 (en) * | 1985-04-10 | 1985-05-15 | Erba Farmitalia | Penem derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
| EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
| IL59081A0 (en) * | 1979-01-10 | 1980-05-30 | Schering Corp | 2-penem compounds and a method for preparing them |
| DE3382761T2 (de) * | 1982-11-29 | 1995-03-09 | Schering Corp | Verfahren zur Herstellung von Penem-Verbindungen. |
| US4614738A (en) * | 1983-03-25 | 1986-09-30 | Schering Corporation | 2-(N-heterocycloaliphaticthio)penems |
| DE3464610D1 (de) * | 1983-06-21 | 1987-08-13 | Pfizer | 2-alkylthiopenem derivatives |
-
1984
- 1984-02-29 DK DK141784A patent/DK141784A/da not_active Application Discontinuation
- 1984-03-07 DE DE8484102429T patent/DE3468107D1/de not_active Expired
- 1984-03-07 EP EP84102429A patent/EP0118875B1/en not_active Expired
- 1984-03-09 AU AU25501/84A patent/AU578238B2/en not_active Ceased
- 1984-03-09 NZ NZ207451A patent/NZ207451A/en unknown
- 1984-03-09 CA CA000449300A patent/CA1254553A/en not_active Expired
- 1984-03-09 GR GR74048A patent/GR79833B/el unknown
- 1984-03-09 PT PT78228A patent/PT78228B/pt not_active IP Right Cessation
- 1984-03-12 IL IL71212A patent/IL71212A/xx unknown
- 1984-03-12 PH PH30381A patent/PH20539A/en unknown
- 1984-03-13 HU HU841000A patent/HU194247B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT78228A (en) | 1984-04-01 |
| PH20539A (en) | 1987-02-09 |
| GR79833B (enEXAMPLES) | 1984-10-31 |
| NZ207451A (en) | 1986-10-08 |
| DE3468107D1 (en) | 1988-01-28 |
| EP0118875B1 (en) | 1987-12-16 |
| HUT34028A (en) | 1985-01-28 |
| DK141784D0 (da) | 1984-02-29 |
| AU578238B2 (en) | 1988-10-20 |
| EP0118875A1 (en) | 1984-09-19 |
| AU2550184A (en) | 1984-09-20 |
| HU194247B (en) | 1988-01-28 |
| DK141784A (da) | 1984-09-15 |
| IL71212A0 (en) | 1984-06-29 |
| IL71212A (en) | 1988-03-31 |
| CA1254553A (en) | 1989-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19920213 |