PT76646A - N-benzoyl n,n-di:propyl iso:glutamine derivs. prepn. - by reacting 5-methoxy 2-methyl indolyl acetic acid with N-hydroxyalkyl N-chloro-alkyl piperazine etc. - Google Patents

N-benzoyl n,n-di:propyl iso:glutamine derivs. prepn. - by reacting 5-methoxy 2-methyl indolyl acetic acid with N-hydroxyalkyl N-chloro-alkyl piperazine etc.

Info

Publication number
PT76646A
PT76646A PT7664683A PT7664683A PT76646A PT 76646 A PT76646 A PT 76646A PT 7664683 A PT7664683 A PT 7664683A PT 7664683 A PT7664683 A PT 7664683A PT 76646 A PT76646 A PT 76646A
Authority
PT
Portugal
Prior art keywords
benzoyl
prepn
hydroxyalkyl
chloro
methoxy
Prior art date
Application number
PT7664683A
Other languages
French (fr)
Portuguese (pt)
Other versions
PT76646B (en
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Priority to PT7664683A priority Critical patent/PT76646B/en
Publication of PT76646A publication Critical patent/PT76646A/en
Publication of PT76646B publication Critical patent/PT76646B/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Prodn. of new derivs. of N-benzoyl N,N-di-n-propyl D,L-isoglutamine of formula (I) (n1 and n2 are 2 or 3, and in which the two tert. amino gps. may be as salts of a pharmaceutical acid). Prepn. comprises reaction of 5-methoxy 2-methyl indolyl acetic acid with a N-hydroxyalkyl N-chloro-alkyl piperazine, reaction of the prod. with p-chlorobenzoyl chloride and further reaction with N-benzoyl N,N-di-n-propyl D,L-isoglutamine. The prods. have anti-inflammatory and anti-rheumatic activity.
PT7664683A 1983-05-05 1983-05-05 PROCESS FOR THE PREPARATION OF NOVEL N-BENZOIL-N ', N'-DI-N-PROPIL-D, L-ISOGLUTAMINE COMPOUNDS PT76646B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PT7664683A PT76646B (en) 1983-05-05 1983-05-05 PROCESS FOR THE PREPARATION OF NOVEL N-BENZOIL-N ', N'-DI-N-PROPIL-D, L-ISOGLUTAMINE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT7664683A PT76646B (en) 1983-05-05 1983-05-05 PROCESS FOR THE PREPARATION OF NOVEL N-BENZOIL-N ', N'-DI-N-PROPIL-D, L-ISOGLUTAMINE COMPOUNDS

Publications (2)

Publication Number Publication Date
PT76646A true PT76646A (en) 1983-06-01
PT76646B PT76646B (en) 1986-01-24

Family

ID=20083281

Family Applications (1)

Application Number Title Priority Date Filing Date
PT7664683A PT76646B (en) 1983-05-05 1983-05-05 PROCESS FOR THE PREPARATION OF NOVEL N-BENZOIL-N ', N'-DI-N-PROPIL-D, L-ISOGLUTAMINE COMPOUNDS

Country Status (1)

Country Link
PT (1) PT76646B (en)

Also Published As

Publication number Publication date
PT76646B (en) 1986-01-24

Similar Documents

Publication Publication Date Title
NO924433L (en) ISOXSAZOL-4-CARBOXYLIC ACID AMIDES AND HYDROXYLYCYLIDE-CYANEDYDIC ACID AMIDES, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND THEIR USE
MA18664A1 (en) AMINO ACID DERIVATIVES USEFUL AS AGENTS AGAINST HYPERTENSION
DK1140860T3 (en) pyrimidine
ES418612A1 (en) 2 (OR 4) Amino 4 (or 2) N-hetero quinazolines
ES8102804A1 (en) Mixed salts of essential or semi-essential amino acids and nitrogen-free analogs thereof
DK438885D0 (en) 3-AMINO-2-BENZOYLACRYLIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF
ES2007177A6 (en) 1-(6-amino-9-purinyl)- beta -D-ribofuranuronic acid amides and thioamides
DE3463650D1 (en) New 2-((2,6-dichlorophenyl)amine)phenylacetoxyacetyl derivatives, the process for preparing the same and their use in therapeutics
ES8306137A1 (en) Carboxylic acid derivatives, their preparation and use as pharmaceuticals.
PT76646A (en) N-benzoyl n,n-di:propyl iso:glutamine derivs. prepn. - by reacting 5-methoxy 2-methyl indolyl acetic acid with N-hydroxyalkyl N-chloro-alkyl piperazine etc.
AU588929B2 (en) Amino acid derivatives
ES8106482A1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them.
ES2001389A6 (en) Substituted toluidines, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors.
ES8800156A1 (en) 3-Pyridylmethylnaphthyl derivatives, process for their preparation and their use as medicaments.
IT1251202B (en) 6-AMINOKINOLONES, SYNTHESIS AND USE AS ANTIBACTERIALS
ES474559A1 (en) Derivatives of BPTI (basic pancreatic trypsin-inhibitor), process for their preparation and their use as medicines.
ES8302633A1 (en) Process for the removal of the formyl group from N-formyl peptides and esters thereof
IL72431A (en) Alkoxyalkylamino and alkoxycarbonyl amino n-(1h-tetrazol-5-yl)benzamides and their preparation
FI102170B1 (en) Process for the preparation of 4- (indol-3-ylmethyl) -3-methoxybenzoic acid derivatives and intermediates useful in the process and their use
IL78700A0 (en) (7-(3-disubstituted amino)-phenyl)pyrazolo(1,5-a)-pyrimidines
FR2354769A1 (en) Nicotinoylcarnitine derivs - having prolonged anti-lipaemic activity
DK159775C (en) 2- (FORMYLAMINO) -N- (1H-TETRAZOL-5-YL) -BENZAMIDE AND SALTS AND HYDRATES THEREOF, AND PROCEDURES FOR PREPARING THEREOF
GB1497689A (en) Method for producing n-(4-fluorophenyl)-2,3-dichloromaleimide
NL7510536A (en) Salts of embelin with primary amines
JPS5340724A (en) Alkylation of aromatic amines

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990731