PT73371B - A method for enhancing the yield of hepatitis a virus - Google Patents

A method for enhancing the yield of hepatitis a virus

Info

Publication number
PT73371B
PT73371B PT73371A PT7337181A PT73371B PT 73371 B PT73371 B PT 73371B PT 73371 A PT73371 A PT 73371A PT 7337181 A PT7337181 A PT 7337181A PT 73371 B PT73371 B PT 73371B
Authority
PT
Portugal
Prior art keywords
hepatitis
virus
enhancing
yield
hav
Prior art date
Application number
PT73371A
Other languages
English (en)
Portuguese (pt)
Other versions
PT73371A (en
Inventor
Henry Z Marcus
William J Mcaleer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT73371A publication Critical patent/PT73371A/pt
Publication of PT73371B publication Critical patent/PT73371B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32451—Methods of production or purification of viral material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT73371A 1980-07-23 1981-07-15 A method for enhancing the yield of hepatitis a virus PT73371B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/171,621 US4301249A (en) 1980-07-23 1980-07-23 High titer production of hepatitis A virus

Publications (2)

Publication Number Publication Date
PT73371A PT73371A (en) 1981-08-01
PT73371B true PT73371B (en) 1983-06-15

Family

ID=22624494

Family Applications (1)

Application Number Title Priority Date Filing Date
PT73371A PT73371B (en) 1980-07-23 1981-07-15 A method for enhancing the yield of hepatitis a virus

Country Status (11)

Country Link
US (1) US4301249A (https=)
EP (1) EP0044793B1 (https=)
JP (1) JPS5753410A (https=)
AT (1) ATE20250T1 (https=)
CA (1) CA1187413A (https=)
DE (1) DE3174765D1 (https=)
DK (1) DK326781A (https=)
ES (1) ES504199A0 (https=)
GR (1) GR74594B (https=)
IE (1) IE51454B1 (https=)
PT (1) PT73371B (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783407A (en) * 1985-09-30 1988-11-08 Merck & Co., Inc. Growth of hepatitus A virus in vero cells
DE3633550A1 (de) * 1986-10-02 1988-04-14 Behringwerke Ag Vaccine gegen hepatitis a
US5268292A (en) * 1988-06-27 1993-12-07 Robertson Betty H Reproducible generation of high yields of hepatitis A virus by cell culture
CA2098510A1 (en) * 1990-12-13 1992-06-14 Kenneth W. Culver Sustained and continuous production of high titers of recombinant viral vectors and transduced target cells for use in gene therapy
US5506129A (en) * 1991-05-24 1996-04-09 Evans Medical Limited Virus production
DZ1706A1 (fr) * 1992-08-07 2002-02-17 Merck & Co Inc Vaccin contre le virus de l'hepatite a.
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
HRP950097A2 (en) * 1994-03-08 1997-06-30 Merck & Co Inc Hepatitis a virus culture process
US5498537A (en) * 1994-03-09 1996-03-12 Cellco, Inc. Serum-free production of packaged viral vector
US20020182730A1 (en) * 1995-07-26 2002-12-05 Micheal L. Gruenberg Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
FR2821947B1 (fr) * 2001-03-12 2003-05-16 Canon Kk Procede et dispositif de validation de parametres definissant une image
US20030134341A1 (en) * 2001-09-19 2003-07-17 Medcell Biologics, Llc. Th1 cell adoptive immunotherapy
US20030134415A1 (en) * 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
US6872549B2 (en) * 2002-03-27 2005-03-29 Immunex Corporation Methods for increasing polypeptide production
WO2008038641A1 (en) * 2006-09-26 2008-04-03 Kyoto University Method of proliferating hepatitis virus, hollow fiber for culturing hepatitis virus-infected cells and utilization of the same
JP5352578B2 (ja) * 2007-05-04 2013-11-27 バクスター・インターナショナル・インコーポレイテッド ウイルスの増殖のための二段階温度プロフィール
JP5692688B2 (ja) * 2008-06-26 2015-04-01 東洋紡株式会社 感染性ｃ型肝炎ウイルス粒子の製造方法、およびその利用
CA2829774C (en) 2011-03-14 2019-09-24 National Research Council Of Canada Method of viral production in cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615024A (en) * 1968-08-26 1971-10-26 Amicon Corp High flow membrane
US3883393A (en) * 1972-05-18 1975-05-13 Us Health Education & Welfare Cell culture on semi-permeable tubular membranes
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
US4087327A (en) * 1976-04-12 1978-05-02 Monsanto Company Mammalion cell culture process
FR2398504A1 (fr) 1977-07-29 1979-02-23 Tours Inst Virologie Culture de virus de l'hepatite a, in vitro. application a la production d'un antigene reactif, d'immunserums specifiques et de vaccins contre l'hepatite a
US4164566A (en) * 1978-08-17 1979-08-14 Merck & Co., Inc. Hepatitis a virus cell culture in vitro
US4301250A (en) * 1979-11-02 1981-11-17 Merck & Co., Inc. Method of producing hepatitis B surface antigen

Also Published As

Publication number Publication date
GR74594B (https=) 1984-06-29
IE811655L (en) 1982-01-23
ES8205016A1 (es) 1982-05-16
US4301249A (en) 1981-11-17
ATE20250T1 (de) 1986-06-15
DK326781A (da) 1982-01-24
EP0044793B1 (en) 1986-06-04
PT73371A (en) 1981-08-01
ES504199A0 (es) 1982-05-16
IE51454B1 (en) 1986-12-24
CA1187413A (en) 1985-05-21
EP0044793A2 (en) 1982-01-27
DE3174765D1 (en) 1986-07-10
EP0044793A3 (en) 1983-01-05
JPS5753410A (en) 1982-03-30

Similar Documents

Publication Publication Date Title
PT73371A (en) A method for enhancing the yield of hepatitis a virus
KR870007282A (ko) 효모에서 b형 간염 바이러스 단백질을 제조하는 방법
GR3007158T3 (https=)
TR22917A (tr) Toprak disi tarima mahsus dayanak
DE3260046D1 (en) Method of producing hepatitis b surface antigen
SE7602751L (sv) Framstellning av n-acyl-l-metionin
DE3068528D1 (en) Process for propagating human hepatitis a virus in in vitro cell culture
ATE10806T1 (de) Verfahren zur herstellung von hepatitis boberfl[chenantigen.
IE781315L (en) Virus cultivation
PT86619A (pt) Process for preparing alkylmelatonins
DK365387D0 (da) Fremgangsmaade ved fremstilling af biogas
DK572181A (da) Fremgangsmaade til fremstilling af 3-oxo-delta1,4-steroider
DK260482A (da) Fremgangsmaade til fremstilling af rent hepatitis b overfladeantigen ud fra human plasma
FI903143A0 (fi) Menetelmä ihmisen nuhaviruksen serotyypittämiseksi
AU1668788A (en) Method of vaccination for hepatitis b virus
NO843750L (no) Immuninterferon og fremgangsmaate ved fremstilling derav
ZA868611B (en) Fermentation methods for hepatitis vaccine production
DK0403015T3 (da) Fremgangsmåde til dyrkning af celler
DK541286D0 (da) Fermentationsmetoder for hepatitis-vaccinefremstilling
GR862720B (en) Fermentation methods for hepatitis vaccine production
GB8622883D0 (en) Expression of hepatitis b viral antigens
RO92552B1 (ro) Procedeu de obtinere a unei compozitii acrilice
SU1540269A1 (ru) Штамм гибридных культивируемых клеток животного mus musculus, используемый для получения моноклональных антител к поверхностному гликопротеину вирусов комплекса клещевого энцефалита