PT72088A - Process for preparing amino substituted tetrahydrobenzindoles - Google Patents

Process for preparing amino substituted tetrahydrobenzindoles

Info

Publication number
PT72088A
PT72088A PT72088A PT7208880A PT72088A PT 72088 A PT72088 A PT 72088A PT 72088 A PT72088 A PT 72088A PT 7208880 A PT7208880 A PT 7208880A PT 72088 A PT72088 A PT 72088A
Authority
PT
Portugal
Prior art keywords
sup
tetrahydrobenzindoles
sub
amino substituted
alkyl
Prior art date
Application number
PT72088A
Other languages
English (en)
Other versions
PT72088B (en
Inventor
John J Baldwin
James H Jones
George F Lundell
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT72088A publication Critical patent/PT72088A/pt
Publication of PT72088B publication Critical patent/PT72088B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
PT72088A 1979-11-23 1980-11-21 Process for preparing amino substituted tetrahydrobenzindoles PT72088B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/096,948 US4282240A (en) 1979-11-23 1979-11-23 Amino substituted tetrahydrobenzindoles

Publications (2)

Publication Number Publication Date
PT72088A true PT72088A (en) 1980-12-01
PT72088B PT72088B (en) 1982-09-01

Family

ID=22259890

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72088A PT72088B (en) 1979-11-23 1980-11-21 Process for preparing amino substituted tetrahydrobenzindoles

Country Status (9)

Country Link
US (1) US4282240A (pt)
EP (1) EP0029581B1 (pt)
JP (1) JPS5687562A (pt)
AT (1) ATE9690T1 (pt)
DE (1) DE3069381D1 (pt)
DK (1) DK497680A (pt)
ES (1) ES497063A0 (pt)
GR (1) GR72131B (pt)
PT (1) PT72088B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU560459B2 (en) * 1982-06-01 1987-04-09 Abbott Laboratories Tetrahydro-benzo(e) isoindolines
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
US4983622A (en) * 1984-02-06 1991-01-08 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
US5026869A (en) * 1984-02-06 1991-06-25 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200130A (en) * 1963-08-27 1965-08-10 Upjohn Co Derivatives of 1, 3, 4, 5-tetrahydro-benz[cd]indoles
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole

Also Published As

Publication number Publication date
GR72131B (pt) 1983-09-19
EP0029581A2 (en) 1981-06-03
PT72088B (en) 1982-09-01
EP0029581A3 (en) 1981-09-02
JPS5687562A (en) 1981-07-16
JPH0139425B2 (pt) 1989-08-21
ES8203343A1 (es) 1982-04-01
DK497680A (da) 1981-05-24
DE3069381D1 (en) 1984-11-08
ES497063A0 (es) 1982-04-01
EP0029581B1 (en) 1984-10-03
ATE9690T1 (de) 1984-10-15
US4282240A (en) 1981-08-04

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