PT71806B - Process for preparing pharmaceutical composition comprising mo-dified polyriboinosonic-polyribocytidylic acid for induction of interferon in primates - Google Patents

Process for preparing pharmaceutical composition comprising mo-dified polyriboinosonic-polyribocytidylic acid for induction of interferon in primates

Info

Publication number
PT71806B
PT71806B PT71806A PT7180680A PT71806B PT 71806 B PT71806 B PT 71806B PT 71806 A PT71806 A PT 71806A PT 7180680 A PT7180680 A PT 7180680A PT 71806 B PT71806 B PT 71806B
Authority
PT
Portugal
Prior art keywords
polyriboinosonic
dified
primates
interferon
induction
Prior art date
Application number
PT71806A
Other languages
English (en)
Other versions
PT71806A (en
Inventor
A Kirk Field
George P Lampson
Alfred A Tytell
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT71806A publication Critical patent/PT71806A/pt
Publication of PT71806B publication Critical patent/PT71806B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT71806A 1979-09-17 1980-09-15 Process for preparing pharmaceutical composition comprising mo-dified polyriboinosonic-polyribocytidylic acid for induction of interferon in primates PT71806B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7600479A 1979-09-17 1979-09-17
US15629580A 1980-06-04 1980-06-04

Publications (2)

Publication Number Publication Date
PT71806A PT71806A (en) 1980-10-01
PT71806B true PT71806B (en) 1982-03-26

Family

ID=26757523

Family Applications (1)

Application Number Title Priority Date Filing Date
PT71806A PT71806B (en) 1979-09-17 1980-09-15 Process for preparing pharmaceutical composition comprising mo-dified polyriboinosonic-polyribocytidylic acid for induction of interferon in primates

Country Status (11)

Country Link
EP (1) EP0025766B1 (pt)
AU (1) AU533471B2 (pt)
DE (1) DE3068533D1 (pt)
DK (1) DK391780A (pt)
ES (1) ES495104A0 (pt)
FI (1) FI802820A (pt)
GR (1) GR70047B (pt)
IL (1) IL61006A (pt)
NO (1) NO802748L (pt)
NZ (1) NZ194880A (pt)
PT (1) PT71806B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2207138B (en) * 1987-07-03 1992-02-05 Nippon Shinyaku Co Ltd Preparation of nucleic acid derivatives.
IL86863A0 (en) * 1987-07-03 1988-11-30 Nippon Shinyaku Co Ltd Nucleic acid derivatives
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
CN1166366C (zh) 1998-05-25 2004-09-15 日本新药株式会社 含有核酸的复合物制剂的制备方法
DK1898948T3 (da) 2005-06-08 2012-04-23 Yisheng Biopharma Singapore Pte Ltd Polyriboinosinsyre-polyribocytidylsyre-baseret adjuvans
US20070166800A1 (en) 2006-01-13 2007-07-19 Haixiang Lin Immunogenic substances comprising a polyinosinic acid-polycytidilic acid based adjuvant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6801650D0 (pt) * 1968-08-20 1973-03-07 R Maes Processo para preparacao de complexos geradores de interferon
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes

Also Published As

Publication number Publication date
NO802748L (no) 1981-03-18
FI802820A (fi) 1981-03-18
EP0025766B1 (en) 1984-07-11
EP0025766A3 (en) 1982-03-31
AU533471B2 (en) 1983-11-24
ES8203613A1 (es) 1982-04-16
PT71806A (en) 1980-10-01
GR70047B (pt) 1982-07-26
DE3068533D1 (en) 1984-08-16
ES495104A0 (es) 1982-04-16
NZ194880A (en) 1983-07-15
DK391780A (da) 1981-03-18
IL61006A0 (en) 1980-11-30
EP0025766A2 (en) 1981-03-25
AU6243480A (en) 1981-03-26
IL61006A (en) 1984-01-31

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