PT3900704T - Copolímero em bloco compreendendo primeiro bloco hidrófilo, segundo bloco hidrófobo, e grupo funcional capaz de se ligar especificamente a tiol - Google Patents
Copolímero em bloco compreendendo primeiro bloco hidrófilo, segundo bloco hidrófobo, e grupo funcional capaz de se ligar especificamente a tiolInfo
- Publication number
- PT3900704T PT3900704T PT199002528T PT19900252T PT3900704T PT 3900704 T PT3900704 T PT 3900704T PT 199002528 T PT199002528 T PT 199002528T PT 19900252 T PT19900252 T PT 19900252T PT 3900704 T PT3900704 T PT 3900704T
- Authority
- PT
- Portugal
- Prior art keywords
- block
- thiol
- hydrophilic
- hydrophobic
- functional group
- Prior art date
Links
- 229920001400 block copolymer Polymers 0.000 title 1
- 125000000524 functional group Chemical group 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 title 1
- 125000003396 thiol group Chemical class [H]S* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4613—Natural-killer cells [NK or NK-T]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
- C08G65/325—Polymers modified by chemical after-treatment with inorganic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
- C08G81/02—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
- C08G81/024—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G
- C08G81/025—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G containing polyether sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/55—Lung
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20180163379 | 2018-12-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3900704T true PT3900704T (pt) | 2023-11-27 |
Family
ID=71102199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT199002528T PT3900704T (pt) | 2018-12-17 | 2019-12-17 | Copolímero em bloco compreendendo primeiro bloco hidrófilo, segundo bloco hidrófobo, e grupo funcional capaz de se ligar especificamente a tiol |
Country Status (18)
Country | Link |
---|---|
US (1) | US20210346308A1 (pt) |
EP (1) | EP3900704B1 (pt) |
JP (2) | JP7265000B2 (pt) |
KR (1) | KR102354882B1 (pt) |
CN (2) | CN117159491A (pt) |
AU (1) | AU2019407590B2 (pt) |
CA (2) | CA3112314C (pt) |
DK (1) | DK3900704T3 (pt) |
ES (1) | ES2966163T3 (pt) |
FI (1) | FI3900704T3 (pt) |
HR (1) | HRP20231550T1 (pt) |
HU (1) | HUE065015T2 (pt) |
PL (1) | PL3900704T3 (pt) |
PT (1) | PT3900704T (pt) |
RS (1) | RS64992B1 (pt) |
SI (1) | SI3900704T1 (pt) |
TW (1) | TWI726540B (pt) |
WO (1) | WO2020130580A1 (pt) |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5929177A (en) * | 1995-08-10 | 1999-07-27 | Kazunori Kataoka | Block polymer having functional groups at both ends |
KR100574341B1 (ko) * | 2003-11-18 | 2006-04-26 | 학교법인 성균관대학 | 썰폰아마이드 이용 pH 민감성 블록공중합체의 제조 방법및 그에 의한 블록공중합체와 마이셀 |
KR100732013B1 (ko) * | 2005-03-18 | 2007-06-25 | 성균관대학교산학협력단 | pH 민감성 블록 공중합체 및 이를 이용한 고분자 마이셀 |
KR100665672B1 (ko) * | 2005-04-13 | 2007-01-09 | 성균관대학교산학협력단 | 새로운 온도 및 pH 민감성 블록 공중합체 및 이를 이용한고분자 하이드로겔 |
CA2648099C (en) * | 2006-03-31 | 2012-05-29 | The Brigham And Women's Hospital, Inc | System for targeted delivery of therapeutic agents |
WO2008124632A1 (en) * | 2007-04-04 | 2008-10-16 | Massachusetts Institute Of Technology | Amphiphilic compound assisted nanoparticles for targeted delivery |
KR20080095130A (ko) * | 2007-04-23 | 2008-10-28 | 한국과학기술연구원 | pH 민감성 블록공중합체를 이용한 약물전달체 제조 및응용 |
KR100838809B1 (ko) * | 2007-05-03 | 2008-06-17 | 성균관대학교산학협력단 | 겔강도가 우수한 온도 및 피에치 민감성 블록 공중합체 및이의 제조방법과 이를 이용한 약물전달체 |
KR100941774B1 (ko) * | 2007-09-06 | 2010-02-11 | 성균관대학교산학협력단 | 인체안전성이 우수한 온도 및 피에치 민감성 블록공중합체및 이의 제조방법과 이를 이용한 약물전달체 |
KR101586866B1 (ko) * | 2010-04-14 | 2016-01-21 | 가톨릭대학교 산학협력단 | 약물 전달을 위한 pH-민감성 나노입자 및 이의 제조방법 |
WO2012040513A1 (en) * | 2010-09-22 | 2012-03-29 | The Board Of Regents Of The University Of Texas System | Compositions and methods for the delivery of beta lapachone |
KR101386176B1 (ko) * | 2010-11-12 | 2014-04-18 | 성균관대학교산학협력단 | 피에이치 민감성 폴리머좀 및 이의 제조방법 |
US9511152B2 (en) * | 2012-04-05 | 2016-12-06 | The Board Of Regents Of The University Of Texas System | Multicolored pH-activatable fluorescence nanoplatform |
CN103316354A (zh) * | 2013-05-27 | 2013-09-25 | 上海纳米技术及应用国家工程研究中心有限公司 | 肿瘤靶向多肽-聚乙二醇-聚乳酸复合物及制备方法和应用 |
KR101554703B1 (ko) * | 2014-02-21 | 2015-09-23 | 전북대학교산학협력단 | 벤조일옥시신남알데히드-폴리에틸렌글리콜 결합 마이셀에 아연 프로토포르피린을 담지한 pH 감응형 항암 전구약물 및 이의 제조방법 |
US10688193B2 (en) * | 2015-07-22 | 2020-06-23 | Gnt Biotech & Medicals Corporation | PH-sensitive linkers for delivering a therapeutic agent |
KR102023058B1 (ko) * | 2016-03-25 | 2019-09-19 | 사회복지법인 삼성생명공익재단 | 이중 이온 pH-민감성 공중합체를 이용한 허혈성 뇌질환 치료용 약물 전달체 |
EP3530291A1 (en) * | 2018-02-27 | 2019-08-28 | Universite De Geneve | Bi-functionalizable amphiphilic diblock copolymers, conjugates and uses thereof |
-
2019
- 2019-12-17 PL PL19900252.8T patent/PL3900704T3/pl unknown
- 2019-12-17 JP JP2021517755A patent/JP7265000B2/ja active Active
- 2019-12-17 HR HRP20231550TT patent/HRP20231550T1/hr unknown
- 2019-12-17 SI SI201930667T patent/SI3900704T1/sl unknown
- 2019-12-17 CN CN202310921842.XA patent/CN117159491A/zh not_active Withdrawn
- 2019-12-17 KR KR1020190168636A patent/KR102354882B1/ko active IP Right Grant
- 2019-12-17 DK DK19900252.8T patent/DK3900704T3/da active
- 2019-12-17 PT PT199002528T patent/PT3900704T/pt unknown
- 2019-12-17 WO PCT/KR2019/017899 patent/WO2020130580A1/ko active Application Filing
- 2019-12-17 EP EP19900252.8A patent/EP3900704B1/en active Active
- 2019-12-17 US US17/278,272 patent/US20210346308A1/en active Pending
- 2019-12-17 ES ES19900252T patent/ES2966163T3/es active Active
- 2019-12-17 HU HUE19900252A patent/HUE065015T2/hu unknown
- 2019-12-17 CN CN201980070001.4A patent/CN112955127B/zh active Active
- 2019-12-17 FI FIEP19900252.8T patent/FI3900704T3/fi active
- 2019-12-17 TW TW108146271A patent/TWI726540B/zh active
- 2019-12-17 AU AU2019407590A patent/AU2019407590B2/en active Active
- 2019-12-17 CA CA3112314A patent/CA3112314C/en active Active
- 2019-12-17 RS RS20231134A patent/RS64992B1/sr unknown
- 2019-12-17 CA CA3206647A patent/CA3206647A1/en active Pending
-
2023
- 2023-04-13 JP JP2023065651A patent/JP2023109749A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2019407590B2 (en) | 2022-08-04 |
ES2966163T3 (es) | 2024-04-18 |
SI3900704T1 (sl) | 2024-01-31 |
AU2019407590A1 (en) | 2021-04-08 |
EP3900704A4 (en) | 2022-02-09 |
KR102354882B1 (ko) | 2022-01-25 |
DK3900704T3 (da) | 2023-12-04 |
CN117159491A (zh) | 2023-12-05 |
US20210346308A1 (en) | 2021-11-11 |
EP3900704A1 (en) | 2021-10-27 |
FI3900704T3 (fi) | 2023-11-30 |
TW202039003A (zh) | 2020-11-01 |
CN112955127A (zh) | 2021-06-11 |
CN112955127B (zh) | 2024-02-27 |
EP3900704B1 (en) | 2023-11-01 |
JP7265000B2 (ja) | 2023-04-25 |
JP2023109749A (ja) | 2023-08-08 |
JP2022510765A (ja) | 2022-01-28 |
PL3900704T3 (pl) | 2024-03-18 |
CA3112314A1 (en) | 2020-06-25 |
KR20200074899A (ko) | 2020-06-25 |
TWI726540B (zh) | 2021-05-01 |
RS64992B1 (sr) | 2024-01-31 |
CA3112314C (en) | 2023-09-19 |
CA3206647A1 (en) | 2020-06-25 |
WO2020130580A1 (ko) | 2020-06-25 |
HRP20231550T1 (hr) | 2024-05-10 |
HUE065015T2 (hu) | 2024-04-28 |
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