PT3511015T - Vacina viva e atenuada e geneticamente estável contra o vírus sincicial respiratório e a sua produção - Google Patents
Vacina viva e atenuada e geneticamente estável contra o vírus sincicial respiratório e a sua produçãoInfo
- Publication number
- PT3511015T PT3511015T PT191508001T PT19150800T PT3511015T PT 3511015 T PT3511015 T PT 3511015T PT 191508001 T PT191508001 T PT 191508001T PT 19150800 T PT19150800 T PT 19150800T PT 3511015 T PT3511015 T PT 3511015T
- Authority
- PT
- Portugal
- Prior art keywords
- production
- respiratory syncytial
- syncytial virus
- live attenuated
- virus vaccine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18521—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18561—Methods of inactivation or attenuation
- C12N2760/18562—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624010P | 2012-04-13 | 2012-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3511015T true PT3511015T (pt) | 2021-04-05 |
Family
ID=47998536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT191508001T PT3511015T (pt) | 2012-04-13 | 2013-03-13 | Vacina viva e atenuada e geneticamente estável contra o vírus sincicial respiratório e a sua produção |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US9624475B2 (pt) |
| EP (3) | EP3875112A1 (pt) |
| DK (1) | DK3511015T3 (pt) |
| ES (1) | ES2863477T3 (pt) |
| PL (1) | PL3511015T3 (pt) |
| PT (1) | PT3511015T (pt) |
| WO (1) | WO2013154728A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3875112A1 (en) * | 2012-04-13 | 2021-09-08 | The United States of America, as Represented By the Secretary, Department of Health and Human Services | Genetically stable live attenuated respiratory syncytial virus vaccine and its production |
| WO2017030997A1 (en) * | 2015-08-14 | 2017-02-23 | Research Institute At Nationwide Children's Hospital | Respiratory syncytial virus having altered ns1 protein function and related materials and methods |
| CA3007408A1 (en) * | 2015-12-11 | 2017-06-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant respiratory syncytial virus strains with mutations in the m2-2 orf providing a range of attenuation phenotypes |
| WO2023154960A1 (en) | 2022-02-14 | 2023-08-17 | University Of Georgia Research Foundation, Inc. | Pan-pneumovirus vaccine compositions and methods of use thereof |
| CN114574521B (zh) * | 2022-03-03 | 2023-09-12 | 山东中医药大学 | 一种基于平衡补偿的重组流感病毒构建方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3224404A1 (de) | 1982-06-30 | 1984-01-05 | LuK Lamellen und Kupplungsbau GmbH, 7580 Bühl | Reibungskupplung sowie verfahren zu deren montage |
| IL105456A (en) * | 1992-04-21 | 1996-12-05 | American Home Prod | Vaccines of attenuated respiratory syncytial virus |
| US6713066B1 (en) * | 1996-07-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 |
| US7846455B2 (en) * | 1996-07-15 | 2010-12-07 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated chimeric respiratory syncytial virus |
| EP2112220A3 (en) * | 1996-07-15 | 2010-01-06 | The Government of the United States of America, as represented by The Department of Health and Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
| EP1287152B1 (en) * | 1999-07-09 | 2008-12-31 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES | Human-bovine chimeric respiratory syncytial virus vaccines |
| EP3875112A1 (en) * | 2012-04-13 | 2021-09-08 | The United States of America, as Represented By the Secretary, Department of Health and Human Services | Genetically stable live attenuated respiratory syncytial virus vaccine and its production |
-
2013
- 2013-03-13 EP EP20217105.4A patent/EP3875112A1/en active Pending
- 2013-03-13 PL PL19150800T patent/PL3511015T3/pl unknown
- 2013-03-13 EP EP19150800.1A patent/EP3511015B1/en active Active
- 2013-03-13 PT PT191508001T patent/PT3511015T/pt unknown
- 2013-03-13 EP EP13712641.3A patent/EP2836231B1/en active Active
- 2013-03-13 ES ES19150800T patent/ES2863477T3/es active Active
- 2013-03-13 WO PCT/US2013/030836 patent/WO2013154728A1/en active Application Filing
- 2013-03-13 DK DK19150800.1T patent/DK3511015T3/da active
- 2013-03-13 US US14/394,226 patent/US9624475B2/en active Active
-
2017
- 2017-03-10 US US15/455,438 patent/US10307476B2/en active Active
-
2019
- 2019-05-29 US US16/425,725 patent/US10980872B2/en active Active
-
2021
- 2021-04-07 US US17/224,819 patent/US20210330782A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3511015B1 (en) | 2020-12-30 |
| PL3511015T3 (pl) | 2021-09-13 |
| DK3511015T3 (da) | 2021-03-15 |
| US10307476B2 (en) | 2019-06-04 |
| WO2013154728A1 (en) | 2013-10-17 |
| US20150118732A1 (en) | 2015-04-30 |
| EP3511015A1 (en) | 2019-07-17 |
| US20170189520A1 (en) | 2017-07-06 |
| ES2863477T3 (es) | 2021-10-11 |
| US20210330782A1 (en) | 2021-10-28 |
| EP3875112A1 (en) | 2021-09-08 |
| US20190282690A1 (en) | 2019-09-19 |
| EP2836231A1 (en) | 2015-02-18 |
| US10980872B2 (en) | 2021-04-20 |
| US9624475B2 (en) | 2017-04-18 |
| EP2836231B1 (en) | 2019-01-09 |
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