PT3445742T - Fosfato de tapentadol cristalino - Google Patents

Fosfato de tapentadol cristalino

Info

Publication number
PT3445742T
PT3445742T PT177169331T PT17716933T PT3445742T PT 3445742 T PT3445742 T PT 3445742T PT 177169331 T PT177169331 T PT 177169331T PT 17716933 T PT17716933 T PT 17716933T PT 3445742 T PT3445742 T PT 3445742T
Authority
PT
Portugal
Prior art keywords
tapentadol phosphate
crystalline tapentadol
crystalline
phosphate
tapentadol
Prior art date
Application number
PT177169331T
Other languages
English (en)
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of PT3445742T publication Critical patent/PT3445742T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PT177169331T 2016-04-19 2017-04-18 Fosfato de tapentadol cristalino PT3445742T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP16166101 2016-04-19
EP16166099 2016-04-19
EP16170781 2016-05-23
EP16170780 2016-05-23

Publications (1)

Publication Number Publication Date
PT3445742T true PT3445742T (pt) 2020-02-19

Family

ID=58537027

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177169331T PT3445742T (pt) 2016-04-19 2017-04-18 Fosfato de tapentadol cristalino

Country Status (7)

Country Link
EP (3) EP3653599B1 (pt)
DK (3) DK3445742T3 (pt)
ES (3) ES2966219T3 (pt)
HR (1) HRP20200029T1 (pt)
PL (3) PL3819287T3 (pt)
PT (1) PT3445742T (pt)
WO (1) WO2017182438A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3650439T (pt) 2010-07-23 2021-03-03 Gruenenthal Gmbh Sais ou cocristais de 3-(3-dimetilamino-1-etil-2-metilpropil)fenol
AU2020100441B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
AU2020100442B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
EP3875080A1 (en) 2020-03-02 2021-09-08 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
EP4003318A1 (en) 2020-03-02 2022-06-01 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
PL3875077T3 (pl) * 2020-03-02 2024-03-11 Grünenthal GmbH Postać dawkowania zapewniająca przedłużone uwalnianie soli kwasu fosforowego tapentadolu
DE202020104285U1 (de) 2020-07-24 2020-12-18 Grünenthal GmbH Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DK1612203T3 (da) 2004-06-28 2007-12-03 Gruenenthal Gmbh Krystallinske former af (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenolhydrochlorid
CN101939287B (zh) 2007-12-07 2014-10-22 格吕伦塔尔有限公司 (1r,2r)-3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚的结晶变体
PT3650439T (pt) 2010-07-23 2021-03-03 Gruenenthal Gmbh Sais ou cocristais de 3-(3-dimetilamino-1-etil-2-metilpropil)fenol
WO2012051246A1 (en) 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof

Also Published As

Publication number Publication date
WO2017182438A1 (en) 2017-10-26
EP3653599B1 (en) 2022-12-14
PL3819287T3 (pl) 2024-03-11
ES2937740T3 (es) 2023-03-30
EP3445742B1 (en) 2019-11-13
DK3819287T3 (da) 2023-12-18
PL3653599T3 (pl) 2023-03-20
EP3819287A1 (en) 2021-05-12
DK3445742T3 (da) 2020-02-24
EP3445742A1 (en) 2019-02-27
HRP20200029T1 (hr) 2020-03-20
EP3653599A1 (en) 2020-05-20
PL3445742T3 (pl) 2020-05-18
ES2966219T3 (es) 2024-04-19
EP3819287B1 (en) 2023-09-20
ES2772806T3 (es) 2020-07-08
DK3653599T3 (da) 2023-01-30

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