PT3320901T - Dimetilaminomicheliolida para utilização no tratamento de fibrose pulmonar - Google Patents
Dimetilaminomicheliolida para utilização no tratamento de fibrose pulmonarInfo
- Publication number
- PT3320901T PT3320901T PT168870509T PT16887050T PT3320901T PT 3320901 T PT3320901 T PT 3320901T PT 168870509 T PT168870509 T PT 168870509T PT 16887050 T PT16887050 T PT 16887050T PT 3320901 T PT3320901 T PT 3320901T
- Authority
- PT
- Portugal
- Prior art keywords
- application
- micheliolide
- dimethylamino
- dimethylamino micheliolide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2016/072445 WO2017128163A1 (zh) | 2016-01-28 | 2016-01-28 | 含笑内酯二甲基胺的应用 |
| EP16887050.9A EP3320901B1 (en) | 2016-01-28 | 2016-01-28 | Dimethylaminomicheliolide for use in the treatment of pulmonary fibrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3320901T true PT3320901T (pt) | 2020-04-24 |
Family
ID=59397048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT168870509T PT3320901T (pt) | 2016-01-28 | 2016-01-28 | Dimetilaminomicheliolida para utilização no tratamento de fibrose pulmonar |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10220019B2 (pt) |
| EP (1) | EP3320901B1 (pt) |
| JP (1) | JP6642892B2 (pt) |
| AU (1) | AU2016390488B9 (pt) |
| CA (1) | CA2995132C (pt) |
| DK (1) | DK3320901T3 (pt) |
| ES (1) | ES2783879T3 (pt) |
| HR (1) | HRP20200473T1 (pt) |
| HU (1) | HUE050456T2 (pt) |
| PL (1) | PL3320901T3 (pt) |
| PT (1) | PT3320901T (pt) |
| WO (1) | WO2017128163A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11634400B2 (en) | 2017-08-19 | 2023-04-25 | University Of Rochester | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents |
| AU2020437428B2 (en) * | 2020-03-26 | 2024-03-28 | Accendatech | Hydrate of dimethylaminomicheliolide fumarate and preparation method therefor and use thereof |
| WO2022041123A1 (zh) * | 2020-08-28 | 2022-03-03 | 洛阳尚德药缘科技有限公司 | 倍半萜内酯类化合物在制备治疗视神经炎药物上的应用 |
| CN113200949B (zh) * | 2021-04-16 | 2022-11-29 | 天津大学 | 一种二甲胺含笑内酯-水杨酸盐及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA00011713A (es) * | 2000-11-28 | 2002-05-31 | Tgt Lab S A De C V | Vectores recombinantes virales y no virales conteniendo el gen humano del activador de plasminogeno derivado de urocinasa y su utilidad en el tratamiento de diversos tipos de fibrosis hepatica, renal, pulmonar, pancreatica, cardiaca y cicatrices hipe |
| KR101421140B1 (ko) * | 2010-04-23 | 2014-07-18 | 난카이 유니버시티 | 메킬리아 락톤 유도체, 그 약제학적 조성물 및 그 제조방법과 용도 |
| KR102077871B1 (ko) * | 2010-11-16 | 2020-02-14 | 유니버시티 오브 써던 캘리포니아 | 체세포 줄기 세포의 비대칭 분열을 향상시키기 위한 ｃｂｐ/카테닌 길항제 |
| AU2013394810B2 (en) * | 2013-07-15 | 2018-05-10 | Accendatech | Uses of sesquiterpene lactone compound and derivative thereof in preparation of drugs |
| CN104418744B (zh) * | 2013-08-29 | 2017-03-01 | 天士力制药集团股份有限公司 | 一种新的丹酚酸化合物t、其制备方法和用途 |
| CN104876899A (zh) * | 2014-02-28 | 2015-09-02 | 天津尚德药缘科技股份有限公司 | 二甲胺含笑内酯富马酸盐及其用途 |
| CN105520933B (zh) | 2014-09-29 | 2020-05-12 | 天津国际生物医药联合研究院 | 含笑内酯二甲基胺的应用 |
-
2016
- 2016-01-28 PT PT168870509T patent/PT3320901T/pt unknown
- 2016-01-28 HU HUE16887050A patent/HUE050456T2/hu unknown
- 2016-01-28 CA CA2995132A patent/CA2995132C/en active Active
- 2016-01-28 DK DK16887050.9T patent/DK3320901T3/da active
- 2016-01-28 AU AU2016390488A patent/AU2016390488B9/en active Active
- 2016-01-28 ES ES16887050T patent/ES2783879T3/es active Active
- 2016-01-28 WO PCT/CN2016/072445 patent/WO2017128163A1/zh active Application Filing
- 2016-01-28 JP JP2018510880A patent/JP6642892B2/ja active Active
- 2016-01-28 PL PL16887050T patent/PL3320901T3/pl unknown
- 2016-01-28 US US15/748,624 patent/US10220019B2/en active Active
- 2016-01-28 EP EP16887050.9A patent/EP3320901B1/en active Active
-
2020
- 2020-03-20 HR HRP20200473TT patent/HRP20200473T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2783879T3 (es) | 2020-09-18 |
| WO2017128163A1 (zh) | 2017-08-03 |
| EP3320901A4 (en) | 2018-11-14 |
| AU2016390488B2 (en) | 2019-12-12 |
| US10220019B2 (en) | 2019-03-05 |
| AU2016390488B9 (en) | 2020-09-17 |
| HRP20200473T1 (hr) | 2020-10-02 |
| US20190000798A1 (en) | 2019-01-03 |
| CA2995132C (en) | 2020-04-21 |
| JP2019503335A (ja) | 2019-02-07 |
| EP3320901A1 (en) | 2018-05-16 |
| PL3320901T3 (pl) | 2020-07-13 |
| EP3320901B1 (en) | 2020-03-04 |
| HUE050456T2 (hu) | 2020-12-28 |
| CA2995132A1 (en) | 2017-08-03 |
| AU2016390488A1 (en) | 2018-03-01 |
| DK3320901T3 (da) | 2020-05-11 |
| JP6642892B2 (ja) | 2020-02-12 |
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