PT2421519T - Bloqueadores do recetor nmda para o tratamento de anemia falciforme - Google Patents

Bloqueadores do recetor nmda para o tratamento de anemia falciforme

Info

Publication number
PT2421519T
PT2421519T PT107139750T PT10713975T PT2421519T PT 2421519 T PT2421519 T PT 2421519T PT 107139750 T PT107139750 T PT 107139750T PT 10713975 T PT10713975 T PT 10713975T PT 2421519 T PT2421519 T PT 2421519T
Authority
PT
Portugal
Prior art keywords
blockers
treatment
nmda receptor
sickle cell
cell anemia
Prior art date
Application number
PT107139750T
Other languages
English (en)
Inventor
Yulienva Bogdanova Anna
Gassmann Max
Goede Jeroen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Zuerich filed Critical Univ Zuerich
Publication of PT2421519T publication Critical patent/PT2421519T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT107139750T 2009-04-23 2010-04-18 Bloqueadores do recetor nmda para o tratamento de anemia falciforme PT2421519T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09005683 2009-04-23

Publications (1)

Publication Number Publication Date
PT2421519T true PT2421519T (pt) 2017-01-26

Family

ID=42224114

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107139750T PT2421519T (pt) 2009-04-23 2010-04-18 Bloqueadores do recetor nmda para o tratamento de anemia falciforme

Country Status (7)

Country Link
US (1) US8680042B2 (pt)
EP (1) EP2421519B1 (pt)
CY (1) CY1118400T1 (pt)
DK (1) DK2421519T3 (pt)
ES (1) ES2612948T3 (pt)
PT (1) PT2421519T (pt)
WO (1) WO2010121973A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2955143C (en) 2010-05-26 2020-02-11 Claudia Hirth-Dietrich The use of sgc stimulators, sgc activators, alone and combinations with pde5 inhibitors for the treatment of systemic sclerosis (ssc).
WO2011161099A1 (de) * 2010-06-25 2011-12-29 Bayer Pharma Aktiengesellschaft Verwendung von stimulatoren und aktivatoren der löslichen guanylatzyklase zur behandlung von sichelzellanämie und konservierung von blutersatzstoffen
RS59687B1 (sr) 2013-01-22 2020-01-31 Vistagen Therapeutics Inc Oblici doziranja i terapeutske primene l-4-hlorkinurenina
US10603311B2 (en) 2015-02-25 2020-03-31 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
US10583171B2 (en) 2015-11-30 2020-03-10 INSERM (Institut National de la Santé et de la Recherche Médicale) NMDAR antagonists for the treatment of diseases associated with angiogenesis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946457B2 (en) * 2001-04-06 2005-09-20 The Trustees Of Columbia University In The City Of New York Methods of treating sickle cell disease

Also Published As

Publication number Publication date
US20120116060A1 (en) 2012-05-10
EP2421519B1 (en) 2016-11-02
US8680042B2 (en) 2014-03-25
ES2612948T3 (es) 2017-05-19
EP2421519A1 (en) 2012-02-29
WO2010121973A1 (en) 2010-10-28
CY1118400T1 (el) 2017-06-28
DK2421519T3 (en) 2017-02-06

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