PT2403495E - Metadoxina para utilização como inibidor da fibrose hepática - Google Patents

Metadoxina para utilização como inibidor da fibrose hepática Download PDF

Info

Publication number
PT2403495E
PT2403495E PT107125197T PT10712519T PT2403495E PT 2403495 E PT2403495 E PT 2403495E PT 107125197 T PT107125197 T PT 107125197T PT 10712519 T PT10712519 T PT 10712519T PT 2403495 E PT2403495 E PT 2403495E
Authority
PT
Portugal
Prior art keywords
metadoxine
inhibitor
hepatic fibrosis
hepatic
fibrosis
Prior art date
Application number
PT107125197T
Other languages
English (en)
Inventor
Massimo Baldacci
Original Assignee
Baldacci Lab Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baldacci Lab Spa filed Critical Baldacci Lab Spa
Publication of PT2403495E publication Critical patent/PT2403495E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT107125197T 2009-03-06 2010-03-04 Metadoxina para utilização como inibidor da fibrose hepática PT2403495E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2009A000333A IT1393338B1 (it) 2009-03-06 2009-03-06 Uso terapeutico della metadoxina come inibitore della fibrosi epatica.

Publications (1)

Publication Number Publication Date
PT2403495E true PT2403495E (pt) 2015-09-17

Family

ID=41202480

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107125197T PT2403495E (pt) 2009-03-06 2010-03-04 Metadoxina para utilização como inibidor da fibrose hepática

Country Status (6)

Country Link
US (1) US20120029031A1 (pt)
EP (1) EP2403495B1 (pt)
ES (1) ES2544780T3 (pt)
IT (1) IT1393338B1 (pt)
PT (1) PT2403495E (pt)
WO (1) WO2010100619A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011061743A1 (en) * 2009-11-18 2011-05-26 Alcobra Ltd. Metadoxine and derivatives thereof for use in the treatment of inflammation and immune-related disorders
KR20150063040A (ko) * 2012-09-26 2015-06-08 유로드러그 레버러토리즈 비. 브이. 간 질환의 치료에 사용하기 위한 메타독신 및 메타독신 연장 방출성 제제
EP3035221A1 (en) * 2014-12-19 2016-06-22 John Rovnan Systems and methods for managing an electronic database

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1131856B (it) * 1980-06-30 1986-06-25 Baldacci Lab Spa Composizione farmaceutica per il trattamento di intossicazioni alcooliche
KR100877600B1 (ko) * 2006-11-30 2009-01-08 재단법인서울대학교산학협력재단 메타독신 및 마늘유를 유효성분으로 함유하는 알코올성지방간 및 지방간성 간염의 예방 및 치료용 약학 조성물

Also Published As

Publication number Publication date
IT1393338B1 (it) 2012-04-20
ITMI20090333A1 (it) 2010-09-07
EP2403495B1 (en) 2015-05-20
US20120029031A1 (en) 2012-02-02
ES2544780T3 (es) 2015-09-03
WO2010100619A1 (en) 2010-09-10
EP2403495A1 (en) 2012-01-11

Similar Documents

Publication Publication Date Title
ZA201700326B (en) Inhibitors of beta-secretase
EP2246336A4 (en) FIBROSIS INHIBITOR
EP2518066A4 (en) NEW ANTIPLATE AGENT
ME02117B (me) 2-aminobenzimidazol-5-karboksamidi kao anti-inflamatorni agensi
IL216145A0 (en) Dihydropyrimidinones for use as bace2 inhibitors
GB0807612D0 (en) New use of surfactant
GB201004311D0 (en) New enzyme inhibitor compounds
HK1165425A1 (zh) 作為 抑制劑的 -環烷基氨基喹諾酮
HK1156306A1 (en) Substituted dihydropyrazolones as inhibitors of hif-prolyl-4-hydroxylases hif--4-
IL220526A0 (en) Kokumi-imparting agent
EP2478768A4 (en) ANTIPHYTOVIRAL AGENT
IL220527A0 (en) Kokumi-imparting agent
IL218967A0 (en) Phenyloxadiazole derivatives as pgds inhibitors
EP2438486A4 (en) Chemically Reinforced Positive Color Composition
GB0907886D0 (en) Corrosion inhibitor
GB0901898D0 (en) Dual calpain-ros inhibitors
IL218500A0 (en) Apogossypolone derivatives as anticaner agents
EP2433502A4 (en) AGENT FOR REMOVING AMERTUME
PT2403495E (pt) Metadoxina para utilização como inibidor da fibrose hepática
PT2464693E (pt) Agente pós-limpeza
GB0901900D0 (en) Dual calpain-ros inhibitors
GB0912788D0 (en) Corrosion inhibitor
GB0903650D0 (en) Glyoalase inhibitors
GB0902661D0 (en) Inhibitors
GB0911102D0 (en) Enzyme inhibitor