PT2300405T - Processos de síntese assimétrica de 6-fluoro-l-dopa e dos seus análogos - Google Patents

Processos de síntese assimétrica de 6-fluoro-l-dopa e dos seus análogos

Info

Publication number
PT2300405T
PT2300405T PT97459846T PT09745984T PT2300405T PT 2300405 T PT2300405 T PT 2300405T PT 97459846 T PT97459846 T PT 97459846T PT 09745984 T PT09745984 T PT 09745984T PT 2300405 T PT2300405 T PT 2300405T
Authority
PT
Portugal
Prior art keywords
dopa
analogs
fluoro
methods
asymmetrically synthesizing
Prior art date
Application number
PT97459846T
Other languages
English (en)
Inventor
Marette Caroline
Gras Emmanuel
Original Assignee
Laboratoires Cyclopharma
Univ Toulouse 3 Paul Sabatier
Centre Nat De La Rech Scient (Cnrs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Cyclopharma, Univ Toulouse 3 Paul Sabatier, Centre Nat De La Rech Scient (Cnrs) filed Critical Laboratoires Cyclopharma
Publication of PT2300405T publication Critical patent/PT2300405T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT97459846T 2008-04-28 2009-04-23 Processos de síntese assimétrica de 6-fluoro-l-dopa e dos seus análogos PT2300405T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0852859A FR2930551B1 (fr) 2008-04-28 2008-04-28 Procedes de synthese asymetrique de la 6-fluoro-l-dopa et de ses analogues

Publications (1)

Publication Number Publication Date
PT2300405T true PT2300405T (pt) 2016-12-09

Family

ID=40140015

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97459846T PT2300405T (pt) 2008-04-28 2009-04-23 Processos de síntese assimétrica de 6-fluoro-l-dopa e dos seus análogos

Country Status (5)

Country Link
EP (1) EP2300405B1 (pt)
ES (1) ES2606053T3 (pt)
FR (1) FR2930551B1 (pt)
PT (1) PT2300405T (pt)
WO (1) WO2009138665A1 (pt)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1245378C (zh) * 2002-01-31 2006-03-15 中国科学院上海原子核研究所 6－[18f]氟－l－多巴的制备方法

Also Published As

Publication number Publication date
FR2930551A1 (fr) 2009-10-30
ES2606053T3 (es) 2017-03-17
WO2009138665A1 (fr) 2009-11-19
EP2300405B1 (fr) 2016-09-07
FR2930551B1 (fr) 2013-07-26
EP2300405A1 (fr) 2011-03-30

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