PT2253307E - L-carnitin for supression of crystallisation - Google Patents

L-carnitin for supression of crystallisation Download PDF

Info

Publication number
PT2253307E
PT2253307E PT100049378T PT10004937T PT2253307E PT 2253307 E PT2253307 E PT 2253307E PT 100049378 T PT100049378 T PT 100049378T PT 10004937 T PT10004937 T PT 10004937T PT 2253307 E PT2253307 E PT 2253307E
Authority
PT
Portugal
Prior art keywords
carnitin
supression
crystallisation
magnesium
spray drying
Prior art date
Application number
PT100049378T
Other languages
Portuguese (pt)
Inventor
Günter Hopf
Original Assignee
Verla Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verla Pharm filed Critical Verla Pharm
Publication of PT2253307E publication Critical patent/PT2253307E/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/20—Feeding-stuffs specially adapted for particular animals for horses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A23L33/165—Complexes or chelates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Aqueous composition (I) comprises a magnesium compound such as magnesium salt or a magnesium complex compound, and L-carnitine. An independent claim is included for a spray drying product, obtained by spray drying the (I).
PT100049378T 2006-05-12 2007-05-02 L-carnitin for supression of crystallisation PT2253307E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06009865A EP1862163A1 (en) 2006-05-12 2006-05-12 L-Carnitin for supression of crystallisation

Publications (1)

Publication Number Publication Date
PT2253307E true PT2253307E (en) 2015-10-05

Family

ID=37198818

Family Applications (2)

Application Number Title Priority Date Filing Date
PT100049378T PT2253307E (en) 2006-05-12 2007-05-02 L-carnitin for supression of crystallisation
PT07008906T PT1854453E (en) 2006-05-12 2007-05-02 Aqueous composition with shelf life stability comprising a magnesium compound and l-carnitine

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT07008906T PT1854453E (en) 2006-05-12 2007-05-02 Aqueous composition with shelf life stability comprising a magnesium compound and l-carnitine

Country Status (9)

Country Link
US (2) US7767712B2 (en)
EP (1) EP1862163A1 (en)
AT (1) ATE498390T1 (en)
AU (1) AU2007201999B2 (en)
CA (1) CA2587579C (en)
DE (1) DE502007006487D1 (en)
ES (2) ES2361227T3 (en)
NZ (1) NZ554970A (en)
PT (2) PT2253307E (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110015267A1 (en) * 2009-07-20 2011-01-20 Deanna Jean Nelson Methods for the preparation and use of aqueous solutions of magnesium valproate hydrate and l-carnitine
GR1009437B (en) * 2017-09-13 2019-01-15 Promopharma Α.Ε. Drinkable dihydro magnesium aspartate-containing solutions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954349A (en) * 1987-09-11 1990-09-04 Ciba-Geigy Corporation Oral magnesium and potassium compositions and use
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
AU1780395A (en) * 1994-05-02 1995-11-09 Omeara (Proprietary) Limited Amino acid, carnitine and magnesium supplementation
GB0001172D0 (en) * 2000-01-20 2000-03-08 Res Del International Limited Physiological medium for perfusing, preserving and storing isolated cell tissue and organ samples
US7115297B2 (en) * 2000-02-22 2006-10-03 Suzanne Jaffe Stillman Nutritionally fortified liquid composition with added value delivery systems/elements/additives
AU2001275165A1 (en) * 2000-06-01 2001-12-11 Ashni Naturaceuticals, Inc. Treatment of side effects associated with alcohol consumption
ES2258426T3 (en) * 2000-06-16 2006-09-01 Matthias Dr. Med. Rath COMPOSITION FOR THE PREVENTION OF DISEASES OF SMOOTH MUSCLES THAT INCLUDE ASCORBATE, ARGININE AND MAGNESIUM.
US6342526B1 (en) * 2000-09-18 2002-01-29 Lonza Ltd. Method for enhancing or achieving training-induced bradycardia with Carnitine
US20050002992A1 (en) * 2003-06-17 2005-01-06 Mccleary Edward Larry Foods, beverages, condiments, spices and salad dressings with specialized supplements
US6579866B2 (en) * 2000-12-28 2003-06-17 Mccleary Larry Composition and method for modulating nutrient partitioning
US20050053673A1 (en) * 2003-09-05 2005-03-10 Shrirang Netke Composition and method for facilitating bone healing
US20050084551A1 (en) * 2003-09-26 2005-04-21 Jensen Claude J. Morinda citrifolia-based oral care compositions and methods
US20050176144A1 (en) * 2004-02-06 2005-08-11 O'daly Jose A. Culture media compositions free of fetal bovine serum

Also Published As

Publication number Publication date
ES2547699T3 (en) 2015-10-08
AU2007201999A1 (en) 2007-11-29
AU2007201999B2 (en) 2011-12-15
ES2361227T3 (en) 2011-06-15
DE502007006487D1 (en) 2011-03-31
CA2587579C (en) 2011-01-04
US20070265339A1 (en) 2007-11-15
CA2587579A1 (en) 2007-11-12
US7767712B2 (en) 2010-08-03
NZ554970A (en) 2008-08-29
EP1862163A1 (en) 2007-12-05
PT1854453E (en) 2011-03-07
ATE498390T1 (en) 2011-03-15
US20100273880A1 (en) 2010-10-28

Similar Documents

Publication Publication Date Title
MX2007013623A (en) External preparation for skin.
WO2008126374A1 (en) Agent for improving alkali resistance of plant and method for improving alkali resistance of plant
WO2009156098A3 (en) Thiadiazolyloxyphenylamidines and use thereof as fungicides
WO2010043682A3 (en) Process for the preparation of compounds useful as inhibitors of sglt
EP2340821A4 (en) Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative of 5-aminolevulinic acid as active ingredient
BRPI0918040A2 (en) additive composition for extending the open time of an aqueous composition, coating, and process and method for preparing a coating additive.
WO2007008684A3 (en) Ligands of melanocortin receptors
WO2009156074A8 (en) Thiadiazolyloxyphenylamidines and use thereof as fungicides
WO2008128639A8 (en) Thiadiazolyl oxyphenyl amidines and the use thereof as a fungicide
WO2009141718A3 (en) Process for the preparation of prostaglandin analogues and intermediates thereof
WO2010031832A3 (en) Synergistic combinations of a macrocyclic inhibitor of hcv and a thiophene-2-carboxylic acid derivative
WO2008053297A3 (en) Pharmaceutical compositions comprising entacapone, levodopa, and carbidopa
IL222991A (en) Tetramic acid derivatives for controlling pests by drenching the soil or by dip application
WO2009089822A3 (en) Use of an acetylsalicylic acid salt for the treatment of viral infections
WO2008053334A3 (en) An improved process for preparing rosuvastatin calcium
WO2008073332A3 (en) Creatine compositions for skin treatment
WO2007016029A3 (en) Diazepinoquinolines, synthesis thereof, and intermediates thereto
WO2008111096A3 (en) Novel prodrugs
WO2012040454A3 (en) Synthesis of substituted salicylaldehyde derivatives
WO2006105482A3 (en) Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same
PT2253307E (en) L-carnitin for supression of crystallisation
WO2009125975A3 (en) Combination of mitiglinide and metformin and process for preparing same
WO2006122020A3 (en) Process for production of 4-biphenylyazetidin-2-ones
WO2008077774A3 (en) Method for obtaining products containing different concentrations of compounds produced by fermentation
PL2010538T3 (en) PROCESS FOR THE PREPARATION OF Ý(1R), 2S¨-2-AMINOPROPIONIC ACID 2-Ý4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLOÝ2,1-f¨Ý1,2,4¨TRIAZIN-6-YLOXY¨-1-METHYLETHYL ESTER