PT2152084E - Método de fabrico de um complexo de ruténio - Google Patents

Método de fabrico de um complexo de ruténio Download PDF

Info

Publication number
PT2152084E
PT2152084E PT87706164T PT08770616T PT2152084E PT 2152084 E PT2152084 E PT 2152084E PT 87706164 T PT87706164 T PT 87706164T PT 08770616 T PT08770616 T PT 08770616T PT 2152084 E PT2152084 E PT 2152084E
Authority
PT
Portugal
Prior art keywords
manufacturing
ruthenium complex
ruthenium
complex
Prior art date
Application number
PT87706164T
Other languages
English (en)
Inventor
Bernhard Keppler
Original Assignee
Niiki Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Niiki Pharma Inc filed Critical Niiki Pharma Inc
Publication of PT2152084E publication Critical patent/PT2152084E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT87706164T 2007-06-11 2008-06-10 Método de fabrico de um complexo de ruténio PT2152084E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94328307P 2007-06-11 2007-06-11

Publications (1)

Publication Number Publication Date
PT2152084E true PT2152084E (pt) 2014-01-23

Family

ID=40130192

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87706164T PT2152084E (pt) 2007-06-11 2008-06-10 Método de fabrico de um complexo de ruténio

Country Status (8)

Country Link
US (1) US8362266B2 (pt)
EP (1) EP2152084B1 (pt)
JP (1) JP5296063B2 (pt)
CN (1) CN101677572B (pt)
CA (1) CA2686834C (pt)
ES (1) ES2441262T3 (pt)
PT (1) PT2152084E (pt)
WO (1) WO2008154553A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013513614A (ja) 2009-12-11 2013-04-22 ニッキ ファーマ インク． 膵臓癌を処置する方法
PT2560638E (pt) * 2010-04-19 2015-07-07 Niiki Pharma Inc Método de tratamento de cancro gástrico
WO2011133827A2 (en) * 2010-04-23 2011-10-27 Niiki Pharma Inc. Method of treating prostate cancer
WO2011139867A2 (en) * 2010-04-29 2011-11-10 Niiki Pharma Inc. Method of treating brain cancer
WO2012061086A2 (en) 2010-10-25 2012-05-10 Niiki Pharma Inc. Method of treating neuroendocrine tumors
TW201251002A (en) * 2010-12-02 2012-12-16 Ube Industries Binuclear metal complex and organic electroluminescent element using same
CN103561745A (zh) * 2011-05-17 2014-02-05 尼基制药收购公司2 用于治疗癌症的药剂和方法
WO2013070988A2 (en) * 2011-11-09 2013-05-16 Niiki Pharma Inc. Method of treating osteosarcoma
CN103601759B (zh) * 2013-10-18 2015-08-19 武汉利宝瑞医药科技有限公司 一种用于治疗肿瘤的钌(iii)络合物的制备方法
IL299223A (en) 2016-03-01 2023-02-01 Intezyne Tech Use of trans-[tetrachlorobis(1H-indazole)rotonate(III)] for cancer treatment
US10611787B2 (en) * 2017-05-05 2020-04-07 Bold Therapeutics, Inc. Manufacture of trans-[tetrachlorobis(1H-indazole)ruthenate (III)] and compositions thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191096B1 (de) 1984-07-24 1989-09-13 ASTA Pharma AG Tumorhemmend wirkende rutheniumverbindungen
IT1230145B (it) * 1989-05-05 1991-10-14 Boehringer Biochemia Srl Complessi di rutenio (iii) come agenti antineoplastici.
DE19612291A1 (de) * 1996-03-28 1997-10-02 Bernhard K Prof Dr Dr Keppler Arzneimittelzubereitungen enthaltend tumorhemmend wirkende Ruthenium(III)-Komplexe
DE10103565B4 (de) * 2001-01-26 2007-06-14 Faustus Forschungs Cie. Translational Cancer Research Gmbh Zusammensetzungen, enthaltend einen Ruthenium(III)-komplex und einen Heterocyclus

Also Published As

Publication number Publication date
EP2152084A1 (en) 2010-02-17
CA2686834C (en) 2014-05-27
CN101677572B (zh) 2013-11-20
EP2152084B1 (en) 2013-12-18
JP2010529202A (ja) 2010-08-26
JP5296063B2 (ja) 2013-09-25
CN101677572A (zh) 2010-03-24
CA2686834A1 (en) 2008-12-18
EP2152084A4 (en) 2012-05-02
US8362266B2 (en) 2013-01-29
ES2441262T3 (es) 2014-02-03
WO2008154553A1 (en) 2008-12-18
US20100094019A1 (en) 2010-04-15

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